ES8801828A1 - Procedimiento para preparar piridazinonas alquil-substituidas - Google Patents

Procedimiento para preparar piridazinonas alquil-substituidas

Info

Publication number
ES8801828A1
ES8801828A1 ES557278A ES557278A ES8801828A1 ES 8801828 A1 ES8801828 A1 ES 8801828A1 ES 557278 A ES557278 A ES 557278A ES 557278 A ES557278 A ES 557278A ES 8801828 A1 ES8801828 A1 ES 8801828A1
Authority
ES
Spain
Prior art keywords
compounds
pharmaceutical preparations
alkyl substituted
alkyl
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES557278A
Other languages
English (en)
Other versions
ES557278A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES557278A0 publication Critical patent/ES557278A0/es
Publication of ES8801828A1 publication Critical patent/ES8801828A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE PIRIDAZINONAS ALQUIL-SUSTITUIDAS, DE FORMULA GENERAL (I), Y SUS FORMAS TAUTOMERICAS, SUS SALES DE ADICION DE ACIDO FARMACEUTICAMENTE ACEPTABLES Y SUS MEZCLAS RACEMICAS. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA GENERAL (II), EN LA QUE XC ES UN ANION DE UN ACIDO MINERAL; Y R2 ES ALQUILO C1-C4, EN PRESENCIA DE COBRE O DE UNA SAL CUPROSA, PARA INTRODUCIR EN EL MISMO UN ATOMO DE HALOGENO O UN GRUPO CIANO, A UNA TEMPERATURA COMPRENDIDA ENTRE 30 Y 150 GRADOS. DE APLICACION EN EL TRATAMIENTO ORAL DE TROMBOSIS.
ES557278A 1984-10-23 1986-12-31 Procedimiento para preparar piridazinonas alquil-substituidas Expired ES8801828A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848426804A GB8426804D0 (en) 1984-10-23 1984-10-23 Pyridazinones preparations

Publications (2)

Publication Number Publication Date
ES557278A0 ES557278A0 (es) 1988-02-16
ES8801828A1 true ES8801828A1 (es) 1988-02-16

Family

ID=10568632

Family Applications (3)

Application Number Title Priority Date Filing Date
ES548119A Expired ES8704479A1 (es) 1984-10-23 1985-10-22 Procedimiento para preparar piridazinonas alquil-sustituidas
ES557277A Expired ES8801802A1 (es) 1984-10-23 1986-12-31 Procedimiento para preparar piridazinonas alquil-substituidas
ES557278A Expired ES8801828A1 (es) 1984-10-23 1986-12-31 Procedimiento para preparar piridazinonas alquil-substituidas

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES548119A Expired ES8704479A1 (es) 1984-10-23 1985-10-22 Procedimiento para preparar piridazinonas alquil-sustituidas
ES557277A Expired ES8801802A1 (es) 1984-10-23 1986-12-31 Procedimiento para preparar piridazinonas alquil-substituidas

Country Status (8)

Country Link
US (2) US4629789A (es)
EP (1) EP0180542A3 (es)
JP (1) JPS61103874A (es)
DK (1) DK483885A (es)
ES (3) ES8704479A1 (es)
GB (1) GB8426804D0 (es)
GR (1) GR852544B (es)
PT (1) PT81348B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3704879A1 (de) * 1987-02-17 1988-08-25 Merck Patent Gmbh Pyridazinonderivate
DE4407873C2 (de) * 1994-03-04 1997-04-10 Mannesmann Ag Verfahren und Vorrichtung zum Kühlen schmelzflüssigen Stahls
US9890127B2 (en) 2013-03-11 2018-02-13 The Broad Institute, Inc. Compounds and compositions for the treatment of cancer
WO2017134231A1 (en) * 2016-02-05 2017-08-10 Bayer Pharma Aktiengesellschaft Compounds, compositions and methods for cancer patient stratification and cancer treatment
EP3661917B1 (en) 2017-08-04 2022-05-11 Bayer Aktiengesellschaft 6-((3-trifluoromethyl)phenyl)-4,5-dihydropyridazin-3(2h)-one derivatives as pde3a and pde3b inhibitors for treating cancer
JOP20200024A1 (ar) 2017-08-04 2020-02-02 Bayer Ag مركبات ثنائي هيدروكساديازينون

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1383906A (en) * 1971-02-22 1974-02-12 Bdh Pharmaceuticals Ltd Pyridazinones
US3975388A (en) * 1971-02-22 1976-08-17 Bdh Pharmaceuticals Limited Pyridazinones
GB1488330A (en) * 1973-12-19 1977-10-12 Smith Kline French Lab Dihydropyridazinones
ATE13294T1 (de) * 1981-03-04 1985-06-15 Ciba Geigy Ag Pyridazinone, verfahren zu ihrer herstellung, pharmazeutische praeparate enthaltend diese verbindungen und deren verwendung.

Also Published As

Publication number Publication date
PT81348A (en) 1985-11-01
ES8704479A1 (es) 1987-04-01
ES8801802A1 (es) 1988-02-16
DK483885A (da) 1986-04-24
EP0180542A3 (en) 1987-04-08
ES557278A0 (es) 1988-02-16
US4699908A (en) 1987-10-13
GB8426804D0 (en) 1984-11-28
EP0180542A2 (en) 1986-05-07
DK483885D0 (da) 1985-10-22
US4629789A (en) 1986-12-16
ES548119A0 (es) 1987-04-01
ES557277A0 (es) 1988-02-16
GR852544B (es) 1986-02-18
JPS61103874A (ja) 1986-05-22
PT81348B (en) 1987-08-05

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