ES8801255A1 - Procedimiento para la obtencion de piridazinonas sustituidas - Google Patents
Procedimiento para la obtencion de piridazinonas sustituidasInfo
- Publication number
- ES8801255A1 ES8801255A1 ES557205A ES557205A ES8801255A1 ES 8801255 A1 ES8801255 A1 ES 8801255A1 ES 557205 A ES557205 A ES 557205A ES 557205 A ES557205 A ES 557205A ES 8801255 A1 ES8801255 A1 ES 8801255A1
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- preparation
- group
- substituted pyridazinones
- pharmaceutical preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE PIRIDAZINONAS SUSTITUIDAS Y DE SUS SALES Y FORMAS TAUTOMERAS, DE FORMULA (I). COMPRENDE LA REACCION DE SOLVOLISIS DE UN COMPUESTO DE FORMULA (II), EN LA QUE R'' REPRESENTA R O UN GRUPO ETER SOLVOLIZABLE O HIDROLIZABLE O EL GRUPO ACILOXI Y OZ'' ES GRUPO ETER O ACILOXI, PARA FORMAR EL COMPUESTO DE FORMULA (I), EN LA QUE R PUEDE SER UNO DE VARIOS TIPOS DE RADICALES Y Z ES HIDROGENO O ACILO. LA SOLVOLISIS SE EFECTUA EN PRESENCIA DE UN ACIDO O UNA BASE, EN UN ALCOHOL O UN HALOGENURO. TAMBIEN SE PUEDE OBTENER POR HIDROGENOLISIS EN PRESENCIA DE UN CATALIZADOR, O DE UN REDUCTOR QUIMICO, A UNA TEMPERATURA COMPRENDIDA ENTRE C20JC Y 150JC. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU EFECTO ANTITROMBOTICO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH394584 | 1984-08-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES557205A0 ES557205A0 (es) | 1988-01-01 |
| ES8801255A1 true ES8801255A1 (es) | 1988-01-01 |
Family
ID=4266863
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES546193A Expired ES8703845A1 (es) | 1984-08-17 | 1985-08-16 | Procedimiento para la obtencion de piridazinonas sustituidas |
| ES557201A Expired ES8801252A1 (es) | 1984-08-17 | 1986-11-14 | Procedimiento para la obtencion de piridazinonas sustituidas |
| ES557203A Expired ES8900108A1 (es) | 1984-08-17 | 1986-11-14 | Procedimiento para la obtencion de piridazinonas sustituidas |
| ES557202A Expired ES8801253A1 (es) | 1984-08-17 | 1986-11-14 | Procedimiento para la obtencion de piridazinonas sustituidas |
| ES557205A Expired ES8801255A1 (es) | 1984-08-17 | 1986-11-14 | Procedimiento para la obtencion de piridazinonas sustituidas |
| ES557204A Expired ES8801254A1 (es) | 1984-08-17 | 1986-11-14 | Procedimiento para la obtencion de piridazinonas sustituidas |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES546193A Expired ES8703845A1 (es) | 1984-08-17 | 1985-08-16 | Procedimiento para la obtencion de piridazinonas sustituidas |
| ES557201A Expired ES8801252A1 (es) | 1984-08-17 | 1986-11-14 | Procedimiento para la obtencion de piridazinonas sustituidas |
| ES557203A Expired ES8900108A1 (es) | 1984-08-17 | 1986-11-14 | Procedimiento para la obtencion de piridazinonas sustituidas |
| ES557202A Expired ES8801253A1 (es) | 1984-08-17 | 1986-11-14 | Procedimiento para la obtencion de piridazinonas sustituidas |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES557204A Expired ES8801254A1 (es) | 1984-08-17 | 1986-11-14 | Procedimiento para la obtencion de piridazinonas sustituidas |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4624951A (es) |
| EP (1) | EP0172141B1 (es) |
| JP (1) | JPS6153270A (es) |
| AT (1) | ATE39114T1 (es) |
| CA (1) | CA1244419A (es) |
| DE (1) | DE3566666D1 (es) |
| DK (1) | DK373985A (es) |
| ES (6) | ES8703845A1 (es) |
| GR (1) | GR851987B (es) |
| PT (1) | PT80955B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4970210A (en) * | 1987-07-17 | 1990-11-13 | Abbott Laboratories | Triazinone lipoxygenase compounds |
| DE3804490A1 (de) * | 1988-02-12 | 1989-08-24 | Heumann Pharma Gmbh & Co | Substituierte 6-phenyldihydro-3(2h)-pyridazinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| EP2970145B1 (en) * | 2013-03-11 | 2020-05-06 | The Broad Institute, Inc. | Compounds and compositions for the treatment of cancer |
| EP3661917B1 (en) | 2017-08-04 | 2022-05-11 | Bayer Aktiengesellschaft | 6-((3-trifluoromethyl)phenyl)-4,5-dihydropyridazin-3(2h)-one derivatives as pde3a and pde3b inhibitors for treating cancer |
| JOP20200024A1 (ar) | 2017-08-04 | 2020-02-02 | Bayer Ag | مركبات ثنائي هيدروكساديازينون |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3689652A (en) * | 1970-10-09 | 1972-09-05 | William Vincent Curran | Method of lowering blood pressure in mammals |
| IL37788A0 (en) * | 1970-10-09 | 1971-12-29 | American Cyanamid Co | New pyridazinone compounds,their preparation and pharmaceutical compositions containing them |
| US3975388A (en) * | 1971-02-22 | 1976-08-17 | Bdh Pharmaceuticals Limited | Pyridazinones |
| US4088762A (en) * | 1971-02-22 | 1978-05-09 | Bdh Pharmaceuticals Limited | 6-(P-PIPERAZINO)-PHENYL-4,5-DIHYDRO-3(2H)pyridazinones |
| GB1383906A (en) * | 1971-02-22 | 1974-02-12 | Bdh Pharmaceuticals Ltd | Pyridazinones |
| US3746712A (en) * | 1971-06-08 | 1973-07-17 | A Ross | 6-(substituted-phenyl)-5-methyl-4,5-dihydro-3(2h)-pyridazinones |
| US3812256A (en) * | 1971-06-08 | 1974-05-21 | American Cyanamid Co | Novel method for lowering blood pressure in mammals |
| US4666902A (en) * | 1983-06-20 | 1987-05-19 | Cassella Aktiengesellschaft | Tetrahydropyridazinone derivatives, processes for their preparation and their use |
-
1985
- 1985-08-08 JP JP60173358A patent/JPS6153270A/ja active Pending
- 1985-08-12 EP EP85810369A patent/EP0172141B1/de not_active Expired
- 1985-08-12 DE DE8585810369T patent/DE3566666D1/de not_active Expired
- 1985-08-12 AT AT85810369T patent/ATE39114T1/de not_active IP Right Cessation
- 1985-08-14 GR GR851987A patent/GR851987B/el unknown
- 1985-08-14 PT PT80955A patent/PT80955B/pt unknown
- 1985-08-15 CA CA000488791A patent/CA1244419A/en not_active Expired
- 1985-08-16 DK DK373985A patent/DK373985A/da not_active Application Discontinuation
- 1985-08-16 ES ES546193A patent/ES8703845A1/es not_active Expired
-
1986
- 1986-01-10 US US06/817,804 patent/US4624951A/en not_active Expired - Fee Related
- 1986-11-14 ES ES557201A patent/ES8801252A1/es not_active Expired
- 1986-11-14 ES ES557203A patent/ES8900108A1/es not_active Expired
- 1986-11-14 ES ES557202A patent/ES8801253A1/es not_active Expired
- 1986-11-14 ES ES557205A patent/ES8801255A1/es not_active Expired
- 1986-11-14 ES ES557204A patent/ES8801254A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES8801252A1 (es) | 1988-01-01 |
| ES8900108A1 (es) | 1988-12-16 |
| DE3566666D1 (en) | 1989-01-12 |
| ES557205A0 (es) | 1988-01-01 |
| ES8801254A1 (es) | 1987-12-16 |
| ES546193A0 (es) | 1987-03-01 |
| ES8703845A1 (es) | 1987-03-01 |
| EP0172141A1 (de) | 1986-02-19 |
| ATE39114T1 (de) | 1988-12-15 |
| ES557202A0 (es) | 1987-12-16 |
| GR851987B (es) | 1985-12-10 |
| JPS6153270A (ja) | 1986-03-17 |
| US4624951A (en) | 1986-11-25 |
| CA1244419A (en) | 1988-11-08 |
| ES557203A0 (es) | 1988-12-16 |
| ES557204A0 (es) | 1987-12-16 |
| ES557201A0 (es) | 1988-01-01 |
| PT80955B (en) | 1987-06-29 |
| DK373985D0 (da) | 1985-08-16 |
| PT80955A (en) | 1985-09-01 |
| DK373985A (da) | 1986-02-18 |
| ES8801253A1 (es) | 1987-12-16 |
| EP0172141B1 (de) | 1988-12-07 |
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