ES8606324A1 - Procedimiento para preparar isocromanos y oxepinas, susti- tuidos - Google Patents
Procedimiento para preparar isocromanos y oxepinas, susti- tuidosInfo
- Publication number
- ES8606324A1 ES8606324A1 ES541295A ES541295A ES8606324A1 ES 8606324 A1 ES8606324 A1 ES 8606324A1 ES 541295 A ES541295 A ES 541295A ES 541295 A ES541295 A ES 541295A ES 8606324 A1 ES8606324 A1 ES 8606324A1
- Authority
- ES
- Spain
- Prior art keywords
- denotes
- atoms
- hydrogen atom
- straight
- branched alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/76—Benzo[c]pyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE ISOCROMANOS Y OXEPINAS, SUSTITUIDOS, DE FORMULA GENERAL (I), EN LA QUE R1 SIGNIFICA UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO LINEAL O RAMIFICADO CON HASTA 4 ATOMOS DE CARBONO; R2 SIGNIFICA UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO LINEAL O RAMIFICADO CON HASTA 4 ATOMOS DE CARBONO; R3 SIGNIFICA UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO; R4 SIGNIFICA UN ATOMO DE HIDROGENO A UN GRUPO ALQUILO; R5, R6, R7 Y R8 SIGNIFICAN ATOMOS DE HIDROGENO O GRUPOS HIDROXI; M SIGNIFICA 1 O 2; Y N SIGNIFICA 1, 2 O 3, Y SUS SALES DE ADICION DE ACIDO FARMACEUTICAMENTE ACEPTABLES. CONSISTE EN HACER REACCIONAR UN DERIVADO DE ISOCROMANO O DE OXEPINA, DE FORMULA GENERAL (II), CON UN FENIL-AMINOPROPIL-ACETONITRILO, DE FORMULA GENERAL (III). DE APLICACION EN EL TRATAMIENTO O PROFILAXIS DE ENFERMEDADES CARDIACAS CORONARIAS Y DE LA HIPERTENSION.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19843409612 DE3409612A1 (de) | 1984-03-16 | 1984-03-16 | Neue substituierte isochromane und oxepine, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8606324A1 true ES8606324A1 (es) | 1986-04-01 |
ES541295A0 ES541295A0 (es) | 1986-04-01 |
Family
ID=6230653
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES541295A Expired ES8606324A1 (es) | 1984-03-16 | 1985-03-15 | Procedimiento para preparar isocromanos y oxepinas, susti- tuidos |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0157206A3 (es) |
JP (1) | JPS60209581A (es) |
KR (1) | KR850006397A (es) |
AU (1) | AU4001785A (es) |
CS (1) | CS247196B2 (es) |
DD (1) | DD234421A5 (es) |
DE (1) | DE3409612A1 (es) |
DK (1) | DK120185A (es) |
ES (1) | ES8606324A1 (es) |
FI (1) | FI851022L (es) |
GR (1) | GR850658B (es) |
HU (1) | HUT37419A (es) |
IL (1) | IL74616A0 (es) |
NO (1) | NO851029L (es) |
PH (1) | PH20880A (es) |
PL (1) | PL252375A1 (es) |
PT (1) | PT80115B (es) |
ZA (1) | ZA851948B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3642331A1 (de) * | 1986-12-11 | 1988-06-23 | Basf Ag | Basisch substituierte phenylacetonitrile, ihre herstellung und diese enthaltende arzneimittel |
JPH03178952A (ja) * | 1989-06-23 | 1991-08-02 | Kyowa Hakko Kogyo Co Ltd | アリールアルキルアミン誘導体 |
EP0450689A1 (en) * | 1990-04-02 | 1991-10-09 | Akzo Nobel N.V. | New isochromane derivatives |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1552004A (en) * | 1976-05-26 | 1979-09-05 | Takeda Chemical Industries Ltd | Isochroman derivatives |
-
1984
- 1984-03-16 DE DE19843409612 patent/DE3409612A1/de not_active Withdrawn
-
1985
- 1985-03-06 EP EP85102518A patent/EP0157206A3/de not_active Withdrawn
- 1985-03-14 GR GR850658A patent/GR850658B/el unknown
- 1985-03-14 DD DD85274121A patent/DD234421A5/de unknown
- 1985-03-14 FI FI851022A patent/FI851022L/fi not_active Application Discontinuation
- 1985-03-14 CS CS851778A patent/CS247196B2/cs unknown
- 1985-03-14 PL PL25237585A patent/PL252375A1/xx unknown
- 1985-03-14 KR KR1019850001630A patent/KR850006397A/ko not_active Application Discontinuation
- 1985-03-15 DK DK120185A patent/DK120185A/da unknown
- 1985-03-15 HU HU85975A patent/HUT37419A/hu unknown
- 1985-03-15 NO NO851029A patent/NO851029L/no unknown
- 1985-03-15 IL IL74616A patent/IL74616A0/xx unknown
- 1985-03-15 PT PT80115A patent/PT80115B/pt unknown
- 1985-03-15 ES ES541295A patent/ES8606324A1/es not_active Expired
- 1985-03-15 AU AU40017/85A patent/AU4001785A/en not_active Abandoned
- 1985-03-15 JP JP60050718A patent/JPS60209581A/ja active Pending
- 1985-03-15 ZA ZA851948A patent/ZA851948B/xx unknown
- 1985-03-18 PH PH31999A patent/PH20880A/en unknown
Also Published As
Publication number | Publication date |
---|---|
NO851029L (no) | 1985-09-17 |
DK120185D0 (da) | 1985-03-15 |
DK120185A (da) | 1985-09-17 |
AU4001785A (en) | 1985-09-19 |
GR850658B (es) | 1985-07-11 |
FI851022A0 (fi) | 1985-03-14 |
PH20880A (en) | 1987-05-27 |
KR850006397A (ko) | 1985-10-05 |
EP0157206A3 (de) | 1986-06-11 |
CS247196B2 (en) | 1986-12-18 |
PL252375A1 (en) | 1985-10-22 |
DE3409612A1 (de) | 1985-09-19 |
HUT37419A (en) | 1985-12-28 |
IL74616A0 (en) | 1985-06-30 |
FI851022L (fi) | 1985-09-17 |
PT80115B (de) | 1987-03-24 |
JPS60209581A (ja) | 1985-10-22 |
EP0157206A2 (de) | 1985-10-09 |
DD234421A5 (de) | 1986-04-02 |
ES541295A0 (es) | 1986-04-01 |
ZA851948B (en) | 1986-11-26 |
PT80115A (de) | 1985-04-01 |
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