ES8801253A1 - Procedimiento para la obtencion de piridazinonas sustituidas - Google Patents

Procedimiento para la obtencion de piridazinonas sustituidas

Info

Publication number
ES8801253A1
ES8801253A1 ES557202A ES557202A ES8801253A1 ES 8801253 A1 ES8801253 A1 ES 8801253A1 ES 557202 A ES557202 A ES 557202A ES 557202 A ES557202 A ES 557202A ES 8801253 A1 ES8801253 A1 ES 8801253A1
Authority
ES
Spain
Prior art keywords
compounds
preparation
group
substituted pyridazinones
pharmaceutical preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES557202A
Other languages
English (en)
Other versions
ES557202A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES8801253A1 publication Critical patent/ES8801253A1/es
Publication of ES557202A0 publication Critical patent/ES557202A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA OBTENER PIRIDAZINONAS SUSTITUIDAS. CONSISTE EN HACER REACCIONAR A UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), EN PRESENCIA DE UNA ALQUILAMINA TERCIARIA (TRIETILAMINA) Y DE UN DISOLVENTE (DIMETILFORMAMIDA) Y ENTRE 0 Y 200JC, PARA OBTENER UN COMPUESTO DE FORMULA (I) Y SUS SALES. SIENDO: R, HAL, ALQUILO INFERIOR O ALCOXI INFERIOR; X, UN GRUPO DISOCIABLE CON HIDROGENO; Y Z, H O ACILO. SE UTILIZAN PARA EL TRATAMIENTO DE LA TROMBOSIS.
ES557202A 1984-08-17 1986-11-14 Procedimiento para la obtencion de piridazinonas sustituidas Expired ES8801253A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH394584 1984-08-17

Publications (2)

Publication Number Publication Date
ES8801253A1 true ES8801253A1 (es) 1987-12-16
ES557202A0 ES557202A0 (es) 1987-12-16

Family

ID=4266863

Family Applications (6)

Application Number Title Priority Date Filing Date
ES546193A Expired ES8703845A1 (es) 1984-08-17 1985-08-16 Procedimiento para la obtencion de piridazinonas sustituidas
ES557205A Expired ES8801255A1 (es) 1984-08-17 1986-11-14 Procedimiento para la obtencion de piridazinonas sustituidas
ES557204A Expired ES8801254A1 (es) 1984-08-17 1986-11-14 Procedimiento para la obtencion de piridazinonas sustituidas
ES557201A Expired ES8801252A1 (es) 1984-08-17 1986-11-14 Procedimiento para la obtencion de piridazinonas sustituidas
ES557202A Expired ES8801253A1 (es) 1984-08-17 1986-11-14 Procedimiento para la obtencion de piridazinonas sustituidas
ES557203A Expired ES8900108A1 (es) 1984-08-17 1986-11-14 Procedimiento para la obtencion de piridazinonas sustituidas

Family Applications Before (4)

Application Number Title Priority Date Filing Date
ES546193A Expired ES8703845A1 (es) 1984-08-17 1985-08-16 Procedimiento para la obtencion de piridazinonas sustituidas
ES557205A Expired ES8801255A1 (es) 1984-08-17 1986-11-14 Procedimiento para la obtencion de piridazinonas sustituidas
ES557204A Expired ES8801254A1 (es) 1984-08-17 1986-11-14 Procedimiento para la obtencion de piridazinonas sustituidas
ES557201A Expired ES8801252A1 (es) 1984-08-17 1986-11-14 Procedimiento para la obtencion de piridazinonas sustituidas

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES557203A Expired ES8900108A1 (es) 1984-08-17 1986-11-14 Procedimiento para la obtencion de piridazinonas sustituidas

Country Status (10)

Country Link
US (1) US4624951A (es)
EP (1) EP0172141B1 (es)
JP (1) JPS6153270A (es)
AT (1) ATE39114T1 (es)
CA (1) CA1244419A (es)
DE (1) DE3566666D1 (es)
DK (1) DK373985A (es)
ES (6) ES8703845A1 (es)
GR (1) GR851987B (es)
PT (1) PT80955B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4970210A (en) * 1987-07-17 1990-11-13 Abbott Laboratories Triazinone lipoxygenase compounds
DE3804490A1 (de) * 1988-02-12 1989-08-24 Heumann Pharma Gmbh & Co Substituierte 6-phenyldihydro-3(2h)-pyridazinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
EP2970145B1 (en) * 2013-03-11 2020-05-06 The Broad Institute, Inc. Compounds and compositions for the treatment of cancer
EP3661917B1 (en) 2017-08-04 2022-05-11 Bayer Aktiengesellschaft 6-((3-trifluoromethyl)phenyl)-4,5-dihydropyridazin-3(2h)-one derivatives as pde3a and pde3b inhibitors for treating cancer
JOP20200024A1 (ar) 2017-08-04 2020-02-02 Bayer Ag مركبات ثنائي هيدروكساديازينون

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3689652A (en) * 1970-10-09 1972-09-05 William Vincent Curran Method of lowering blood pressure in mammals
IL37788A0 (en) * 1970-10-09 1971-12-29 American Cyanamid Co New pyridazinone compounds,their preparation and pharmaceutical compositions containing them
US3975388A (en) * 1971-02-22 1976-08-17 Bdh Pharmaceuticals Limited Pyridazinones
US4088762A (en) * 1971-02-22 1978-05-09 Bdh Pharmaceuticals Limited 6-(P-PIPERAZINO)-PHENYL-4,5-DIHYDRO-3(2H)pyridazinones
GB1383906A (en) * 1971-02-22 1974-02-12 Bdh Pharmaceuticals Ltd Pyridazinones
US3812256A (en) * 1971-06-08 1974-05-21 American Cyanamid Co Novel method for lowering blood pressure in mammals
US3746712A (en) * 1971-06-08 1973-07-17 A Ross 6-(substituted-phenyl)-5-methyl-4,5-dihydro-3(2h)-pyridazinones
US4666902A (en) * 1983-06-20 1987-05-19 Cassella Aktiengesellschaft Tetrahydropyridazinone derivatives, processes for their preparation and their use

Also Published As

Publication number Publication date
GR851987B (es) 1985-12-10
US4624951A (en) 1986-11-25
ES546193A0 (es) 1987-03-01
ES8703845A1 (es) 1987-03-01
ES8801252A1 (es) 1988-01-01
ES557204A0 (es) 1987-12-16
ES8801255A1 (es) 1988-01-01
ES8801254A1 (es) 1987-12-16
PT80955A (en) 1985-09-01
DK373985A (da) 1986-02-18
ES557203A0 (es) 1988-12-16
EP0172141B1 (de) 1988-12-07
DE3566666D1 (en) 1989-01-12
PT80955B (en) 1987-06-29
ATE39114T1 (de) 1988-12-15
JPS6153270A (ja) 1986-03-17
ES8900108A1 (es) 1988-12-16
DK373985D0 (da) 1985-08-16
ES557201A0 (es) 1988-01-01
ES557202A0 (es) 1987-12-16
ES557205A0 (es) 1988-01-01
CA1244419A (en) 1988-11-08
EP0172141A1 (de) 1986-02-19

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