ES8801802A1 - Procedimiento para preparar piridazinonas alquil-substituidas - Google Patents
Procedimiento para preparar piridazinonas alquil-substituidasInfo
- Publication number
- ES8801802A1 ES8801802A1 ES557277A ES557277A ES8801802A1 ES 8801802 A1 ES8801802 A1 ES 8801802A1 ES 557277 A ES557277 A ES 557277A ES 557277 A ES557277 A ES 557277A ES 8801802 A1 ES8801802 A1 ES 8801802A1
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- pharmaceutical preparations
- alkyl substituted
- alkyl
- processes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE PIRIDAZINONAS ALQUIL-SUSTITUIDAS, DE FORMULA GENERAL (I), Y SUS FORMAS TAUTOMERAS, SUS SALES DE ADICION DE ACIDO FARMACEUTICAMENTE ACEPTABLES Y SUS MEZCLAS RACEMICAS. CONSISTE EN REDUCIR, EN UN COMPUESTO DE FORMULA GENERAL (II), EN LA QUE R1 ES AMINO; Y R2 ES ALQUILO C1-C4, EL GRUPO NITRO CATALITICAMENTE O CON UN AGENTE REDUCTOR QUIMICO TAL COMO UN CATALIZADOR DE METAL NOBLE O UN METAL PESADO REDUCTOR, EN PRESENCIA DE UN DISOLVENTE ORGANICO INERTE, PARA OBTENER UN GRUPO AMINO. DE APLICACION EN LA PREPARACION DE PRODUCTOS FARMACEUTICOS ANTITROMBOTICOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848426804A GB8426804D0 (en) | 1984-10-23 | 1984-10-23 | Pyridazinones preparations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES557277A0 ES557277A0 (es) | 1988-02-16 |
| ES8801802A1 true ES8801802A1 (es) | 1988-02-16 |
Family
ID=10568632
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES548119A Expired ES8704479A1 (es) | 1984-10-23 | 1985-10-22 | Procedimiento para preparar piridazinonas alquil-sustituidas |
| ES557277A Expired ES8801802A1 (es) | 1984-10-23 | 1986-12-31 | Procedimiento para preparar piridazinonas alquil-substituidas |
| ES557278A Expired ES8801828A1 (es) | 1984-10-23 | 1986-12-31 | Procedimiento para preparar piridazinonas alquil-substituidas |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES548119A Expired ES8704479A1 (es) | 1984-10-23 | 1985-10-22 | Procedimiento para preparar piridazinonas alquil-sustituidas |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES557278A Expired ES8801828A1 (es) | 1984-10-23 | 1986-12-31 | Procedimiento para preparar piridazinonas alquil-substituidas |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US4629789A (es) |
| EP (1) | EP0180542A3 (es) |
| JP (1) | JPS61103874A (es) |
| DK (1) | DK483885A (es) |
| ES (3) | ES8704479A1 (es) |
| GB (1) | GB8426804D0 (es) |
| GR (1) | GR852544B (es) |
| PT (1) | PT81348B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3704879A1 (de) * | 1987-02-17 | 1988-08-25 | Merck Patent Gmbh | Pyridazinonderivate |
| DE4407873C2 (de) * | 1994-03-04 | 1997-04-10 | Mannesmann Ag | Verfahren und Vorrichtung zum Kühlen schmelzflüssigen Stahls |
| EP2970145B1 (en) * | 2013-03-11 | 2020-05-06 | The Broad Institute, Inc. | Compounds and compositions for the treatment of cancer |
| AR107529A1 (es) * | 2016-02-05 | 2018-05-09 | Bayer Pharma AG | Compuestos, composiciones y métodos para la estratificación de pacientes de cáncer y su tratamiento |
| US11897867B2 (en) | 2017-08-04 | 2024-02-13 | Bayer Aktiengesellschaft | 6-phenyl-4,5-dihydropyridazin-3(2H)-one derivatives as PDE3A and PDE3B inhibitors for treating cancer |
| JOP20200024A1 (ar) | 2017-08-04 | 2020-02-02 | Bayer Ag | مركبات ثنائي هيدروكساديازينون |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1383906A (en) * | 1971-02-22 | 1974-02-12 | Bdh Pharmaceuticals Ltd | Pyridazinones |
| US3975388A (en) * | 1971-02-22 | 1976-08-17 | Bdh Pharmaceuticals Limited | Pyridazinones |
| GB1488330A (en) * | 1973-12-19 | 1977-10-12 | Smith Kline French Lab | Dihydropyridazinones |
| FI72718C (fi) * | 1981-03-04 | 1987-07-10 | Ciba Geigy Ag | Foerfarande foer framstaellning av terapeutiskt verkande, substituerade 6-(4-morfolino-fenyl)-4,5-dihydro- 3(2h)-pyridazinoner och deras syraadditionssalter. |
-
1984
- 1984-10-23 GB GB848426804A patent/GB8426804D0/en active Pending
-
1985
- 1985-10-17 EP EP85810472A patent/EP0180542A3/en not_active Withdrawn
- 1985-10-21 PT PT81348A patent/PT81348B/pt unknown
- 1985-10-22 US US06/789,995 patent/US4629789A/en not_active Expired - Fee Related
- 1985-10-22 GR GR852544A patent/GR852544B/el unknown
- 1985-10-22 ES ES548119A patent/ES8704479A1/es not_active Expired
- 1985-10-22 JP JP60234664A patent/JPS61103874A/ja active Pending
- 1985-10-22 DK DK483885A patent/DK483885A/da not_active Application Discontinuation
-
1986
- 1986-08-06 US US06/893,836 patent/US4699908A/en not_active Expired - Fee Related
- 1986-12-31 ES ES557277A patent/ES8801802A1/es not_active Expired
- 1986-12-31 ES ES557278A patent/ES8801828A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GR852544B (es) | 1986-02-18 |
| PT81348B (en) | 1987-08-05 |
| ES8704479A1 (es) | 1987-04-01 |
| ES8801828A1 (es) | 1988-02-16 |
| US4629789A (en) | 1986-12-16 |
| US4699908A (en) | 1987-10-13 |
| ES557277A0 (es) | 1988-02-16 |
| EP0180542A3 (en) | 1987-04-08 |
| DK483885D0 (da) | 1985-10-22 |
| ES557278A0 (es) | 1988-02-16 |
| EP0180542A2 (en) | 1986-05-07 |
| GB8426804D0 (en) | 1984-11-28 |
| JPS61103874A (ja) | 1986-05-22 |
| DK483885A (da) | 1986-04-24 |
| PT81348A (en) | 1985-11-01 |
| ES548119A0 (es) | 1987-04-01 |
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