ES8800921A1 - Procedimiento para la obtencion del antipoda levogiro y dextrogiro del racemato del acido 5-cloro-6-(3-clorobencenosulfonil)-1,3-benzodioxol-2-carboxilico - Google Patents

Procedimiento para la obtencion del antipoda levogiro y dextrogiro del racemato del acido 5-cloro-6-(3-clorobencenosulfonil)-1,3-benzodioxol-2-carboxilico

Info

Publication number
ES8800921A1
ES8800921A1 ES555599A ES555599A ES8800921A1 ES 8800921 A1 ES8800921 A1 ES 8800921A1 ES 555599 A ES555599 A ES 555599A ES 555599 A ES555599 A ES 555599A ES 8800921 A1 ES8800921 A1 ES 8800921A1
Authority
ES
Spain
Prior art keywords
pharmaceutical compositions
preparation
racemate
salts
cases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES555599A
Other languages
English (en)
Other versions
ES555599A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES555599A0 publication Critical patent/ES555599A0/es
Publication of ES8800921A1 publication Critical patent/ES8800921A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)

Abstract

METODO DE OBTENER EL ANTIPODA LEVOGIRO Y DEXTROGIRO DEL RACEMATO DEL ACIDO 5-CLORO-6-(3-CLOROBENCENOSULFONIL)-1,3-BENZODIOXOL-2-CARBOXILICO. CONSISTE EN TRANSFORMAR EL GRUPO A2 DEL COMPUESTO DE FORMULA (II) MEDIANTE HIDROLISIS ACIDA O ALCALINA EN EL GRUPO CARBOXI EN FORMA LIBRE O EN FORMA DE SAL, PARA OBTENER UN COMPUESTO DE FORMULA (I), Y UN RACEMATO DE FORMULA (I) OBTENIDO SE DESCOMPONE EN LOS ANTIPODAS OPTICOS, Y/O UN COMPUESTO LIBRE OBTENIDO SE TRANSFORMA EN UNA SAL CON UNA BASE, O CON UN COMPUESTO DE ESTOS SE LIBERA DE UNA SAL OBTENIDA. TIENE APLICACIONES FARMACEUTICAS POR SU EFICACIA URICOSURICA
ES555599A 1984-04-06 1986-06-02 Procedimiento para la obtencion del antipoda levogiro y dextrogiro del racemato del acido 5-cloro-6-(3-clorobencenosulfonil)-1,3-benzodioxol-2-carboxilico Expired ES8800921A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH175284 1984-04-06

Publications (2)

Publication Number Publication Date
ES555599A0 ES555599A0 (es) 1987-12-01
ES8800921A1 true ES8800921A1 (es) 1987-12-01

Family

ID=4217732

Family Applications (4)

Application Number Title Priority Date Filing Date
ES541965A Expired ES8800192A1 (es) 1984-04-06 1985-04-03 Procedimiento para la obtencion del acido 5-cloro-6-(3-clorobencenosulfonil)-1,3-benzodioxol-2-carboxilico.
ES555600A Expired ES8706662A1 (es) 1984-04-06 1986-06-02 Procedimiento para la obtencion del antipoda levogiro y dextrogiro del racemato del acido 5-cloro-6-(3-clorobencenosulfonil)-1,3-benzodioxol-2-carboxilico
ES555601A Expired ES8800922A1 (es) 1984-04-06 1986-06-02 Procedimiento para la obtencion del antipoda levogiro y dextrogiro del racemato del acido 5-cloro-6-(3-clorobencenosulfonil)-1,3-benzodioxol-2-carboxilico
ES555599A Expired ES8800921A1 (es) 1984-04-06 1986-06-02 Procedimiento para la obtencion del antipoda levogiro y dextrogiro del racemato del acido 5-cloro-6-(3-clorobencenosulfonil)-1,3-benzodioxol-2-carboxilico

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES541965A Expired ES8800192A1 (es) 1984-04-06 1985-04-03 Procedimiento para la obtencion del acido 5-cloro-6-(3-clorobencenosulfonil)-1,3-benzodioxol-2-carboxilico.
ES555600A Expired ES8706662A1 (es) 1984-04-06 1986-06-02 Procedimiento para la obtencion del antipoda levogiro y dextrogiro del racemato del acido 5-cloro-6-(3-clorobencenosulfonil)-1,3-benzodioxol-2-carboxilico
ES555601A Expired ES8800922A1 (es) 1984-04-06 1986-06-02 Procedimiento para la obtencion del antipoda levogiro y dextrogiro del racemato del acido 5-cloro-6-(3-clorobencenosulfonil)-1,3-benzodioxol-2-carboxilico

Country Status (11)

Country Link
EP (1) EP0158596A3 (es)
JP (1) JPS60228473A (es)
AU (1) AU4089185A (es)
DK (1) DK153285A (es)
ES (4) ES8800192A1 (es)
FI (1) FI851335L (es)
GR (1) GR850845B (es)
IL (1) IL74780A0 (es)
NO (1) NO851385L (es)
PT (1) PT80222B (es)
ZA (1) ZA852554B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007005205A (es) 2004-10-29 2007-05-11 Kalypsys Inc Compuestos biciclicos sulfonilo-sustituidos como moduladores de receptores activados por el proliferador de la peroxisoma.
BRPI0619282B8 (pt) 2005-10-25 2021-05-25 Kalypsys Inc sal, e composição farmacêutica
WO2008091863A1 (en) 2007-01-23 2008-07-31 Kalypsys, Inc. Sulfonyl-substituted bicyclic compounds as ppar modulators for the treatment of non-alcoholic steatohepatitis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR75464B (es) * 1981-04-24 1984-07-20 Ciba Geigy
DE3374408D1 (en) * 1982-10-22 1987-12-17 Ciba Geigy Ag Benzodioxole derivatives, process for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EP0158596A3 (de) 1986-08-13
IL74780A0 (en) 1985-07-31
GR850845B (es) 1985-11-25
DK153285D0 (da) 1985-04-03
FI851335L (fi) 1985-10-07
ES8706662A1 (es) 1987-07-01
ES555599A0 (es) 1987-12-01
AU4089185A (en) 1985-10-10
PT80222A (en) 1985-05-01
NO851385L (no) 1985-10-07
ES555601A0 (es) 1987-12-01
ES555600A0 (es) 1987-07-01
JPS60228473A (ja) 1985-11-13
DK153285A (da) 1985-10-07
ZA852554B (en) 1985-11-27
EP0158596A2 (de) 1985-10-16
ES8800192A1 (es) 1987-11-01
ES541965A0 (es) 1987-11-01
ES8800922A1 (es) 1987-12-01
FI851335A0 (fi) 1985-04-03
PT80222B (en) 1987-04-13

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