ES8706662A1 - Procedimiento para la obtencion del antipoda levogiro y dextrogiro del racemato del acido 5-cloro-6-(3-clorobencenosulfonil)-1,3-benzodioxol-2-carboxilico - Google Patents
Procedimiento para la obtencion del antipoda levogiro y dextrogiro del racemato del acido 5-cloro-6-(3-clorobencenosulfonil)-1,3-benzodioxol-2-carboxilicoInfo
- Publication number
- ES8706662A1 ES8706662A1 ES555600A ES555600A ES8706662A1 ES 8706662 A1 ES8706662 A1 ES 8706662A1 ES 555600 A ES555600 A ES 555600A ES 555600 A ES555600 A ES 555600A ES 8706662 A1 ES8706662 A1 ES 8706662A1
- Authority
- ES
- Spain
- Prior art keywords
- pharmaceutical compositions
- preparation
- racemate
- salts
- cases
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Abstract
METODO DE OBTENER ANTIPODA LEVOGIRO Y DEXTROGIRO DEL RACEMATO DEL ACIDO 5-CLORO-6-(3-CLORBENCENOSULFONIL)-1,3-BENZODIOXOL-2-CARBOXILICO. CONSISTE EN OXIDAR UN COMPUESTO DE FORMULA (II), PARA OBTENER EL COMPUESTO DESEADO DE FORMULA (I) Y SUS SALES CON BASE Y ESTERES DE ALQUILO INFERIOR DEL RACEMATO. LA OXIDACION SE REALIZA MEDIANTE PEROXIDO DE HIDROGENO, EN UN DISOLVENTE ORGANICO U ORGANICO-ACUOSO INERTE, TAL COMO ACETICO CONTENIENDO AGUA, A TEMPERATURAS ENTRE 60 Y 100GC, Y CON UNA CANTIDAD MAS DE DOS VECES MOLAR DE PEROXIDO DE HIDROGENO CUANDO COMO PRODUCTO DE OXIDACION SE HA DE OBTENER UN COMPUESTO SULFONILO. TIENE APLICACIONES FARMACEUTICAS POR SU EFECTO URICOSURICO. *FORMULA*
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH175284 | 1984-04-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8706662A1 true ES8706662A1 (es) | 1987-07-01 |
ES555600A0 ES555600A0 (es) | 1987-07-01 |
Family
ID=4217732
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES541965A Expired ES8800192A1 (es) | 1984-04-06 | 1985-04-03 | Procedimiento para la obtencion del acido 5-cloro-6-(3-clorobencenosulfonil)-1,3-benzodioxol-2-carboxilico. |
ES555600A Expired ES8706662A1 (es) | 1984-04-06 | 1986-06-02 | Procedimiento para la obtencion del antipoda levogiro y dextrogiro del racemato del acido 5-cloro-6-(3-clorobencenosulfonil)-1,3-benzodioxol-2-carboxilico |
ES555601A Expired ES8800922A1 (es) | 1984-04-06 | 1986-06-02 | Procedimiento para la obtencion del antipoda levogiro y dextrogiro del racemato del acido 5-cloro-6-(3-clorobencenosulfonil)-1,3-benzodioxol-2-carboxilico |
ES555599A Expired ES8800921A1 (es) | 1984-04-06 | 1986-06-02 | Procedimiento para la obtencion del antipoda levogiro y dextrogiro del racemato del acido 5-cloro-6-(3-clorobencenosulfonil)-1,3-benzodioxol-2-carboxilico |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES541965A Expired ES8800192A1 (es) | 1984-04-06 | 1985-04-03 | Procedimiento para la obtencion del acido 5-cloro-6-(3-clorobencenosulfonil)-1,3-benzodioxol-2-carboxilico. |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES555601A Expired ES8800922A1 (es) | 1984-04-06 | 1986-06-02 | Procedimiento para la obtencion del antipoda levogiro y dextrogiro del racemato del acido 5-cloro-6-(3-clorobencenosulfonil)-1,3-benzodioxol-2-carboxilico |
ES555599A Expired ES8800921A1 (es) | 1984-04-06 | 1986-06-02 | Procedimiento para la obtencion del antipoda levogiro y dextrogiro del racemato del acido 5-cloro-6-(3-clorobencenosulfonil)-1,3-benzodioxol-2-carboxilico |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0158596A3 (es) |
JP (1) | JPS60228473A (es) |
AU (1) | AU4089185A (es) |
DK (1) | DK153285A (es) |
ES (4) | ES8800192A1 (es) |
FI (1) | FI851335L (es) |
GR (1) | GR850845B (es) |
IL (1) | IL74780A0 (es) |
NO (1) | NO851385L (es) |
PT (1) | PT80222B (es) |
ZA (1) | ZA852554B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2007005205A (es) | 2004-10-29 | 2007-05-11 | Kalypsys Inc | Compuestos biciclicos sulfonilo-sustituidos como moduladores de receptores activados por el proliferador de la peroxisoma. |
BRPI0619282B8 (pt) | 2005-10-25 | 2021-05-25 | Kalypsys Inc | sal, e composição farmacêutica |
WO2008091863A1 (en) | 2007-01-23 | 2008-07-31 | Kalypsys, Inc. | Sulfonyl-substituted bicyclic compounds as ppar modulators for the treatment of non-alcoholic steatohepatitis |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR75464B (es) * | 1981-04-24 | 1984-07-20 | Ciba Geigy | |
DE3374408D1 (en) * | 1982-10-22 | 1987-12-17 | Ciba Geigy Ag | Benzodioxole derivatives, process for their preparation and pharmaceutical compositions containing them |
-
1985
- 1985-03-29 EP EP85810142A patent/EP0158596A3/de not_active Withdrawn
- 1985-04-02 IL IL74780A patent/IL74780A0/xx unknown
- 1985-04-03 PT PT80222A patent/PT80222B/pt not_active IP Right Cessation
- 1985-04-03 NO NO851385A patent/NO851385L/no unknown
- 1985-04-03 FI FI851335A patent/FI851335L/fi not_active Application Discontinuation
- 1985-04-03 DK DK153285A patent/DK153285A/da not_active IP Right Cessation
- 1985-04-03 ES ES541965A patent/ES8800192A1/es not_active Expired
- 1985-04-04 ZA ZA852554A patent/ZA852554B/xx unknown
- 1985-04-04 AU AU40891/85A patent/AU4089185A/en not_active Abandoned
- 1985-04-04 GR GR850845A patent/GR850845B/el unknown
- 1985-04-05 JP JP60071260A patent/JPS60228473A/ja active Pending
-
1986
- 1986-06-02 ES ES555600A patent/ES8706662A1/es not_active Expired
- 1986-06-02 ES ES555601A patent/ES8800922A1/es not_active Expired
- 1986-06-02 ES ES555599A patent/ES8800921A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
EP0158596A3 (de) | 1986-08-13 |
IL74780A0 (en) | 1985-07-31 |
GR850845B (es) | 1985-11-25 |
DK153285D0 (da) | 1985-04-03 |
FI851335L (fi) | 1985-10-07 |
ES555599A0 (es) | 1987-12-01 |
AU4089185A (en) | 1985-10-10 |
PT80222A (en) | 1985-05-01 |
NO851385L (no) | 1985-10-07 |
ES555601A0 (es) | 1987-12-01 |
ES555600A0 (es) | 1987-07-01 |
JPS60228473A (ja) | 1985-11-13 |
DK153285A (da) | 1985-10-07 |
ZA852554B (en) | 1985-11-27 |
EP0158596A2 (de) | 1985-10-16 |
ES8800192A1 (es) | 1987-11-01 |
ES541965A0 (es) | 1987-11-01 |
ES8800921A1 (es) | 1987-12-01 |
ES8800922A1 (es) | 1987-12-01 |
FI851335A0 (fi) | 1985-04-03 |
PT80222B (en) | 1987-04-13 |
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