ES8707934A1 - Un procedimiento para la preparacion de derivados de piridina. - Google Patents

Un procedimiento para la preparacion de derivados de piridina.

Info

Publication number
ES8707934A1
ES8707934A1 ES555240A ES555240A ES8707934A1 ES 8707934 A1 ES8707934 A1 ES 8707934A1 ES 555240 A ES555240 A ES 555240A ES 555240 A ES555240 A ES 555240A ES 8707934 A1 ES8707934 A1 ES 8707934A1
Authority
ES
Spain
Prior art keywords
preparing
same
lower alkyl
pyridine derivatives
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES555240A
Other languages
English (en)
Other versions
ES555240A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of ES555240A0 publication Critical patent/ES555240A0/es
Publication of ES8707934A1 publication Critical patent/ES8707934A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE PIRIDINA, DE FORMULA GENERAL (I), Y SUS SALES FARMACEUTICAMENTE ACEPTABLES DEL MISMO. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA GENERAL (II), CON UNA ALQUILAMINA INFERIOR DE FORMULA GENERAL: R3NH2, PARA OBTENER UN COMPUESTO DE FORMULA GENERAL (III). OPCIONALMENTE SE HIDROLIZA EL GRUPO ESTER DE LA POSICION 4 DEL COMPUESTO DE FORMULA GENERAL (III), PARA DAR UN GRUPO CARBOXILO, Y OPCIONALMENTE SE ESTERIFICA EL GRUPO CARBOXILO DE LA POSICION 4 CUANDO SE INTRODUCE UN GRUPO ALQUILO DIFERENTE. DE APLICACION COMO FARMACOS PARA EL TRATAMIENTO DE ENFERMEDADES ALERGICAS, TALES COMO EL ASMA, LA ALERGIA AL POLEN Y SIMILARES.
ES555240A 1985-05-23 1986-05-22 Un procedimiento para la preparacion de derivados de piridina. Expired ES8707934A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11064285 1985-05-23

Publications (2)

Publication Number Publication Date
ES555240A0 ES555240A0 (es) 1987-09-01
ES8707934A1 true ES8707934A1 (es) 1987-09-01

Family

ID=14540880

Family Applications (1)

Application Number Title Priority Date Filing Date
ES555240A Expired ES8707934A1 (es) 1985-05-23 1986-05-22 Un procedimiento para la preparacion de derivados de piridina.

Country Status (14)

Country Link
US (1) US4691018A (es)
EP (1) EP0203435B1 (es)
JP (1) JPS6253966A (es)
KR (1) KR860008980A (es)
CN (1) CN86103501A (es)
AT (1) ATE55992T1 (es)
AU (1) AU587251B2 (es)
CA (1) CA1240332A (es)
DE (1) DE3673693D1 (es)
ES (1) ES8707934A1 (es)
HU (1) HU195486B (es)
SU (1) SU1419517A3 (es)
YU (1) YU83686A (es)
ZA (1) ZA863706B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4877795A (en) * 1987-01-30 1989-10-31 Kissei Pharmaceutical Co., Ltd. 4H-quinolizin-4-one compounds useful for the treatment of allergic bronchial asthma, allergic rhinitis atropic dermatitis and the like
DE3703963A1 (de) * 1987-02-10 1988-08-18 Hoechst Ag Pyridin-2,4- und 2,,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben, sowie arzneimittel auf basis dieser verbindungen
US4904657A (en) * 1987-09-24 1990-02-27 Kissei Pharmaceutical Co., Ltd. 4H-quinolizin-4-one compounds exhibiting therapeutic activities
JP2746832B2 (ja) * 1993-05-14 1998-05-06 大鵬薬品工業株式会社 眼局所抗アレルギー剤
TW264385B (es) * 1993-05-14 1995-12-01 Taiho Pharmaceutical Co Ltd
WO2010141883A1 (en) * 2009-06-04 2010-12-09 The Regents Of The University Of Colorado Compounds that modulate autoimmunity and methods of using the same
WO2012162697A1 (en) 2011-05-26 2012-11-29 The Regents Of The University Of Colorado, A Body Corporate Compounds that modulate autoimmunity and methods of using the same
US10568435B2 (en) 2012-08-30 2020-02-25 Huntleigh Technology Limited Multi-layered patient support cover system
EP3247384B1 (en) 2015-01-14 2023-10-04 The Regents of the University of Colorado, a body corporate In vitro method of diagnosis of type 1 diabetes with insulin mimotopes
EP3432877B1 (en) 2016-03-24 2023-01-11 ImmunoMolecular Therapeutics, Inc. D-alpha-methyldopa for treating autoimmune disease
US11052060B2 (en) 2018-02-12 2021-07-06 The Regents Of The University Of Colorado, A Body Corporate Compounds and methods for treating autoimmunity
US11013707B2 (en) 2018-03-23 2021-05-25 The Regents Of The University Of Colorado, A Body Corporate Administration of oral methyldopa

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3174885D1 (en) * 1981-02-03 1986-07-31 Ici Plc Process for the extraction of metal values and novel metal extractants
JPS58105920A (ja) * 1981-12-17 1983-06-24 Chugai Pharmaceut Co Ltd 抗癌剤
JPS58159465A (ja) * 1982-03-17 1983-09-21 Chugai Pharmaceut Co Ltd ピリジン誘導体

Also Published As

Publication number Publication date
EP0203435B1 (en) 1990-08-29
YU83686A (en) 1988-06-30
CN86103501A (zh) 1987-01-21
ES555240A0 (es) 1987-09-01
JPS6253966A (ja) 1987-03-09
HU195486B (en) 1988-05-30
DE3673693D1 (de) 1990-10-04
AU5726786A (en) 1986-11-27
EP0203435A3 (en) 1988-01-07
CA1240332A (en) 1988-08-09
US4691018A (en) 1987-09-01
KR860008980A (ko) 1986-12-19
ATE55992T1 (de) 1990-09-15
AU587251B2 (en) 1989-08-10
SU1419517A3 (ru) 1988-08-23
HUT41735A (en) 1987-05-28
JPH0225906B2 (es) 1990-06-06
EP0203435A2 (en) 1986-12-03
ZA863706B (en) 1987-01-28

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