ES8707712A1 - Un procedimiento para preparar derivados de oxisalicilamida - Google Patents

Un procedimiento para preparar derivados de oxisalicilamida

Info

Publication number
ES8707712A1
ES8707712A1 ES550825A ES550825A ES8707712A1 ES 8707712 A1 ES8707712 A1 ES 8707712A1 ES 550825 A ES550825 A ES 550825A ES 550825 A ES550825 A ES 550825A ES 8707712 A1 ES8707712 A1 ES 8707712A1
Authority
ES
Spain
Prior art keywords
group
preparation
lower alkyl
intermediates
nhr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES550825A
Other languages
English (en)
Other versions
ES550825A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astra Lakemedel AB
Original Assignee
Astra Lakemedel AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Lakemedel AB filed Critical Astra Lakemedel AB
Publication of ES550825A0 publication Critical patent/ES550825A0/es
Publication of ES8707712A1 publication Critical patent/ES8707712A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

METODO DE PREPARAR DERIVADOS DE OXISALICILAMIDA. CONSISTE EN SOMETER A UNA REACCION DE SUSTITUCION EN N A UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA R3-CH2-X2, EN UN DISOLVENTE ORGANICO A TEMPERATURA ENTRE 0 Y 100JC Y EN PRESENCIA DE UNA BASE, PARA OBTENER DERIVADOS DE OXISALICILAMIDA DE FORMULA (I) DONDE ZI, QUE ES Z1, Z2 O Z3, SON DIFERENTES ENTRE SI Y SON OH, OR1, NH2 Y OTROS, DONDE R1 ES UN GRUPO FORMILO, ACILO O ALCOXICARBONILO Y OTROS; R2 ES H, UN HALOGENO, UN ALQUILO INFERIOR O UN TRIFLUOROALQUILO INFERIOR; Y R3 ES H, UN GRUPO ALQUILO INFERIOR, UN GRUPO ALQUENILO Y OTROS. TIENEN APLICACIONES FARMACEUTICAS PARA TRATAR LA ESQUIZOFRENIA, LA DEPRESION Y OTROS.
ES550825A 1984-01-31 1986-01-13 Un procedimiento para preparar derivados de oxisalicilamida Expired ES8707712A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8400478A SE8400478D0 (sv) 1984-01-31 1984-01-31 Oxysalicylamido derivatives

Publications (2)

Publication Number Publication Date
ES550825A0 ES550825A0 (es) 1987-08-16
ES8707712A1 true ES8707712A1 (es) 1987-08-16

Family

ID=20354529

Family Applications (3)

Application Number Title Priority Date Filing Date
ES539955A Expired ES8609239A1 (es) 1984-01-31 1985-01-30 Un procedimiento de preparar derivados de oxisalicilamida
ES550826A Expired ES8801199A1 (es) 1984-01-31 1986-01-13 Un procedimiento para preparar derivados de oxisalicilamida
ES550825A Expired ES8707712A1 (es) 1984-01-31 1986-01-13 Un procedimiento para preparar derivados de oxisalicilamida

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES539955A Expired ES8609239A1 (es) 1984-01-31 1985-01-30 Un procedimiento de preparar derivados de oxisalicilamida
ES550826A Expired ES8801199A1 (es) 1984-01-31 1986-01-13 Un procedimiento para preparar derivados de oxisalicilamida

Country Status (25)

Country Link
EP (1) EP0156776B1 (es)
JP (1) JPH07103097B2 (es)
AT (1) ATE41770T1 (es)
AU (1) AU575113B2 (es)
CA (1) CA1253869A (es)
CY (1) CY1544A (es)
DD (1) DD231349A5 (es)
DE (1) DE3569111D1 (es)
DK (1) DK38685A (es)
ES (3) ES8609239A1 (es)
FI (1) FI83771C (es)
GB (1) GB2153354B (es)
GR (1) GR850268B (es)
HK (1) HK53090A (es)
HU (1) HU198684B (es)
IE (1) IE57888B1 (es)
IS (1) IS1442B6 (es)
MY (1) MY102377A (es)
NO (1) NO171363C (es)
NZ (1) NZ210939A (es)
PH (2) PH22430A (es)
PT (1) PT79900B (es)
SE (1) SE8400478D0 (es)
SG (1) SG35290G (es)
ZA (1) ZA85158B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5446147A (en) * 1992-04-03 1995-08-29 Trustees Of The University Of Pennsylvania Fluorinated and iodinated dopamine agents

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5822110B2 (ja) * 1977-08-08 1983-05-06 塩野義製薬株式会社 ベンズアミド誘導体の合成法
FR2440946A2 (fr) * 1978-01-20 1980-06-06 Ile De France Nouveaux benzamides heterocycliques substitues, leurs procedes de preparation et leur application comme modificateurs du comportement
SE411118B (sv) * 1978-03-23 1979-12-03 Astra Laekemedel Ab Ett forfarande for framstellning av 2,6-dialkoxibensamider med terapentiska egenskaper
JPS55130957A (en) * 1979-03-30 1980-10-11 Kyowa Hakko Kogyo Co Ltd Production of benzamide derivative
SE8101536L (sv) * 1981-03-11 1982-09-12 Astra Laekemedel Ab Bensamid-derivat
SE8205135D0 (sv) * 1982-09-09 1982-09-09 Astra Laekemedel Ab Benzamido-derivatives

Also Published As

Publication number Publication date
ZA85158B (en) 1985-09-25
GB2153354B (en) 1987-10-21
IS1442B6 (is) 1990-12-14
SE8400478D0 (sv) 1984-01-31
PH24046A (en) 1990-03-05
PH22430A (en) 1988-09-12
HK53090A (en) 1990-07-20
FI83771C (fi) 1991-08-26
GB2153354A (en) 1985-08-21
FI850398L (fi) 1985-08-01
NO171363B (no) 1992-11-23
ES8801199A1 (es) 1987-12-16
DE3569111D1 (en) 1989-05-03
IE57888B1 (en) 1993-05-05
AU575113B2 (en) 1988-07-21
DD231349A5 (de) 1985-12-24
JPS60178859A (ja) 1985-09-12
ES550825A0 (es) 1987-08-16
ATE41770T1 (de) 1989-04-15
NO850244L (no) 1985-08-01
DK38685A (da) 1985-08-01
HUT37750A (en) 1986-02-28
MY102377A (en) 1992-06-17
IE850220L (en) 1985-07-31
FI850398A0 (fi) 1985-01-30
EP0156776A1 (en) 1985-10-02
PT79900A (en) 1985-02-01
CA1253869A (en) 1989-05-09
JPH07103097B2 (ja) 1995-11-08
NZ210939A (en) 1988-10-28
AU3808885A (en) 1985-08-08
DK38685D0 (da) 1985-01-29
NO171363C (no) 1993-03-03
PT79900B (en) 1987-02-03
FI83771B (fi) 1991-05-15
ES550826A0 (es) 1987-12-16
EP0156776B1 (en) 1989-03-29
HU198684B (en) 1989-11-28
CY1544A (en) 1991-03-22
IS2974A7 (is) 1985-08-01
ES8609239A1 (es) 1986-09-01
GR850268B (es) 1985-05-28
SG35290G (en) 1990-07-13
GB8502095D0 (en) 1985-02-27
ES539955A0 (es) 1986-09-01

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