ES8704957A1 - Procedimiento para preparar alfa-aminoacidos sustituidos - Google Patents
Procedimiento para preparar alfa-aminoacidos sustituidosInfo
- Publication number
- ES8704957A1 ES8704957A1 ES541689A ES541689A ES8704957A1 ES 8704957 A1 ES8704957 A1 ES 8704957A1 ES 541689 A ES541689 A ES 541689A ES 541689 A ES541689 A ES 541689A ES 8704957 A1 ES8704957 A1 ES 8704957A1
- Authority
- ES
- Spain
- Prior art keywords
- amino acids
- group
- preparation
- ester
- pharmaceutical compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001371 alpha-amino acids Chemical class 0.000 title abstract 2
- 235000008206 alpha-amino acids Nutrition 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 150000002148 esters Chemical group 0.000 abstract 2
- 206010021143 Hypoxia Diseases 0.000 abstract 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003412 degenerative effect Effects 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 230000001146 hypoxic effect Effects 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
- 239000011574 phosphorus Substances 0.000 abstract 1
- 201000000980 schizophrenia Diseases 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
- 125000003831 tetrazolyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848408059A GB8408059D0 (en) | 1984-03-29 | 1984-03-29 | Organic compounds |
| GB848421091A GB8421091D0 (en) | 1984-08-20 | 1984-08-20 | Organic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES541689A0 ES541689A0 (es) | 1987-04-16 |
| ES8704957A1 true ES8704957A1 (es) | 1987-04-16 |
Family
ID=26287523
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES541689A Expired ES8704957A1 (es) | 1984-03-29 | 1985-03-28 | Procedimiento para preparar alfa-aminoacidos sustituidos |
| ES555560A Expired ES8706622A1 (es) | 1984-03-29 | 1986-05-30 | Procedimiento para preparar alfa-aminoacidos sustituidos |
| ES555559A Expired ES8802015A1 (es) | 1984-03-29 | 1986-05-30 | Procedimiento para preparar alfa-aminoacidos sustituidos |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES555560A Expired ES8706622A1 (es) | 1984-03-29 | 1986-05-30 | Procedimiento para preparar alfa-aminoacidos sustituidos |
| ES555559A Expired ES8802015A1 (es) | 1984-03-29 | 1986-05-30 | Procedimiento para preparar alfa-aminoacidos sustituidos |
Country Status (16)
| Country | Link |
|---|---|
| AU (1) | AU4042585A (sv) |
| BE (1) | BE902040A (sv) |
| DE (1) | DE3510858A1 (sv) |
| DK (1) | DK139185A (sv) |
| ES (3) | ES8704957A1 (sv) |
| FI (1) | FI851234L (sv) |
| FR (1) | FR2562076A1 (sv) |
| GB (1) | GB2156818B (sv) |
| GR (1) | GR850770B (sv) |
| HU (1) | HUT40447A (sv) |
| IL (1) | IL74734A0 (sv) |
| IT (1) | IT1199964B (sv) |
| LU (1) | LU85826A1 (sv) |
| NL (1) | NL8500847A (sv) |
| PT (1) | PT80178B (sv) |
| SE (1) | SE8501548L (sv) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5217963A (en) * | 1985-05-24 | 1993-06-08 | Ciba-Geigy Corporation | Certain phosphonic acid quinoline-2-carboxylic acids, esters or amides useful for treatment of disorders responsive to N-methyl D-aspartate receptor blockade |
| US4906621A (en) * | 1985-05-24 | 1990-03-06 | Ciba-Geigy Corporation | Certain 2-carboxypiperidyl-alkylene phosphonic acids and esters thereof useful for the treatment of disorders responsive to N-methyl-D-aspartate receptor blockade |
| US4746653A (en) * | 1986-02-28 | 1988-05-24 | Ciba-Geigy Corporation | Certain hetero phosphonic acid derivatives of 2-piperidine or 2-tetrahydropyridinecarboxylates and esters thereof which are useful for the treatment of disorders responsive to blockade of the NMDA receptor in mammals |
| US5175153A (en) * | 1987-11-30 | 1992-12-29 | Warner-Lambert Company | Substituted alpha-amino acids having pharmaceutical activity |
| IT1216096B (it) * | 1988-03-15 | 1990-02-22 | Farmaceutica Italiana S P A S | L_piroglutamil_l_cisteina, dipeptide ad elevata attivita'anticatarattogena e composizioni farmaceutiche che lo contengono. |
| EP0436612A4 (en) * | 1988-09-30 | 1992-05-20 | Australian Commercial Research & Development Limited | Amino acid transport proteins, amino acid analogues, assay apparatus, uses thereof for treatment and diagnosis of cancer |
| US5179085A (en) * | 1989-03-15 | 1993-01-12 | Warner-Lambert Company | N-substituted α-amino acids and derivatives thereof having pharmaceutical activity |
| US5500419A (en) * | 1989-09-19 | 1996-03-19 | Merrell Dow Pharmaceuticals Inc. | NMDA antagonists |
| JPH03236315A (ja) * | 1989-12-05 | 1991-10-22 | Nippon Oil & Fats Co Ltd | 抗精神病薬 |
| US5238958A (en) * | 1990-02-26 | 1993-08-24 | Warner-Lambert Company | Substituted α-amino acids having selected acidic moieties for use as excitatory amino acid antagonists in pharmaceuticals |
| IT1249650B (it) * | 1991-05-29 | 1995-03-09 | Poli Ind Chimica Spa | N-(5-tioxo-l-prolil)-l-cisteina e suoi derivati, loro preparazione ed impiego terapeutico |
| IT1256178B (it) * | 1992-11-30 | 1995-11-29 | Lorenzo Ferrari | Composti ad attivita' terapeutica utili per il trattamento di malattieconnesse ad una carenza di glutatione, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono. |
| DE4433555B4 (de) * | 1994-09-07 | 2005-04-28 | Guenther Oehme | Wasserlösliche chirale und achirale Phosphine, Verfahren zu ihrer Herstellung und ihre Verwendung |
| DE10045831A1 (de) * | 2000-09-14 | 2002-04-04 | Gruenenthal Gmbh | Thio-Aminosäuren |
| DK1317426T3 (da) | 2000-09-14 | 2006-01-09 | Gruenenthal Gmbh | Betal-thio-aminosyrer |
| AU2002325740B2 (en) * | 2001-09-18 | 2007-07-26 | Vasogen Ireland Limited | Apoptosis-mimicking synthetic entities and use thereof in medical treatment |
| EP3427729A1 (en) | 2017-07-13 | 2019-01-16 | Paris Sciences et Lettres - Quartier Latin | Probenecid for use in treating epileptic diseases, disorders or conditions |
| WO2019048450A1 (en) | 2017-09-08 | 2019-03-14 | Ludwig-Maximilians-Universität München | SULFOXIDE-BASED REAGENT FOR MASS SPECTROMETRY |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2104079B (en) * | 1981-08-14 | 1985-08-21 | London Polytech | New aminoacid isomers, their production and their medicinal use |
-
1985
- 1985-03-22 HU HU851104A patent/HUT40447A/hu unknown
- 1985-03-22 NL NL8500847A patent/NL8500847A/nl not_active Application Discontinuation
- 1985-03-26 GB GB08507794A patent/GB2156818B/en not_active Expired
- 1985-03-26 DE DE19853510858 patent/DE3510858A1/de not_active Withdrawn
- 1985-03-27 GR GR850770A patent/GR850770B/el unknown
- 1985-03-27 FR FR8504729A patent/FR2562076A1/fr active Pending
- 1985-03-27 PT PT80178A patent/PT80178B/pt unknown
- 1985-03-27 DK DK139185A patent/DK139185A/da not_active Application Discontinuation
- 1985-03-27 IT IT47877/85A patent/IT1199964B/it active
- 1985-03-27 IL IL74734A patent/IL74734A0/xx unknown
- 1985-03-27 FI FI851234A patent/FI851234L/fi not_active Application Discontinuation
- 1985-03-27 AU AU40425/85A patent/AU4042585A/en not_active Abandoned
- 1985-03-28 SE SE8501548A patent/SE8501548L/sv not_active Application Discontinuation
- 1985-03-28 ES ES541689A patent/ES8704957A1/es not_active Expired
- 1985-03-28 BE BE1/011221A patent/BE902040A/fr not_active IP Right Cessation
- 1985-03-29 LU LU85826A patent/LU85826A1/fr unknown
-
1986
- 1986-05-30 ES ES555560A patent/ES8706622A1/es not_active Expired
- 1986-05-30 ES ES555559A patent/ES8802015A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB8507794D0 (en) | 1985-05-01 |
| IT8547877A0 (it) | 1985-03-27 |
| ES555560A0 (es) | 1987-07-01 |
| PT80178A (en) | 1985-04-01 |
| LU85826A1 (fr) | 1985-12-12 |
| ES8802015A1 (es) | 1988-03-16 |
| ES8706622A1 (es) | 1987-07-01 |
| FR2562076A1 (fr) | 1985-10-04 |
| ES555559A0 (es) | 1988-03-16 |
| IT8547877A1 (it) | 1986-09-27 |
| ES541689A0 (es) | 1987-04-16 |
| GB2156818B (en) | 1987-10-21 |
| IL74734A0 (en) | 1985-06-30 |
| FI851234L (fi) | 1985-09-30 |
| NL8500847A (nl) | 1985-10-16 |
| AU4042585A (en) | 1985-10-03 |
| PT80178B (en) | 1987-03-20 |
| SE8501548D0 (sv) | 1985-03-28 |
| IT1199964B (it) | 1989-01-05 |
| FI851234A0 (fi) | 1985-03-27 |
| BE902040A (fr) | 1985-09-30 |
| DK139185A (da) | 1985-09-30 |
| GB2156818A (en) | 1985-10-16 |
| DK139185D0 (da) | 1985-03-27 |
| GR850770B (sv) | 1985-07-23 |
| HUT40447A (en) | 1986-12-28 |
| SE8501548L (sv) | 1985-09-30 |
| DE3510858A1 (de) | 1985-10-10 |
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