ES8704506A1 - Procedimiento para preparar nuevos compuestos de antracicli-na - Google Patents

Procedimiento para preparar nuevos compuestos de antracicli-na

Info

Publication number
ES8704506A1
ES8704506A1 ES549951A ES549951A ES8704506A1 ES 8704506 A1 ES8704506 A1 ES 8704506A1 ES 549951 A ES549951 A ES 549951A ES 549951 A ES549951 A ES 549951A ES 8704506 A1 ES8704506 A1 ES 8704506A1
Authority
ES
Spain
Prior art keywords
rod
roa
deoxyfucose
rhodinose
rhodosamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES549951A
Other languages
English (en)
Other versions
ES549951A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES549951A0 publication Critical patent/ES549951A0/es
Publication of ES8704506A1 publication Critical patent/ES8704506A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS DE ANTRACICLINA, DE FORMULA (I), Y DE SUS SALES DE ADICION DE ACIDOS FISIOLOGICAMENTE COMPATIBLES. CONSISTE EN FERMENTAR EL MICROORGANISMO STREPTOMYCES PURPURASCENS DSM 2658 EN UN MEDIO NUTRITIVO ADECUADO, EN CONDICIONES AEROBIAS; DESPUES DE UN TIEMPO DE FERMENTACION COMPRENDIDO ENTRE 20 Y 36 HORAS, AÑADIR UN INHIBIDOR QUIMICO, PARA OBTENER EL COMPUESTO DE FORMULA (I), EN LA QUE R1 PUEDE SER VARIOS TIPOS DE RADICALES, QUE SE SEPARA DEL MEDIO SIGUIENDO METODOS CONVENCIONALES. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU EFECTO ANTIBACTERIANO.
ES549951A 1984-12-18 1985-12-16 Procedimiento para preparar nuevos compuestos de antracicli-na Expired ES8704506A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843446052 DE3446052A1 (de) 1984-12-18 1984-12-18 Anthracyclin-derivate, ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
ES549951A0 ES549951A0 (es) 1987-04-01
ES8704506A1 true ES8704506A1 (es) 1987-04-01

Family

ID=6253030

Family Applications (1)

Application Number Title Priority Date Filing Date
ES549951A Expired ES8704506A1 (es) 1984-12-18 1985-12-16 Procedimiento para preparar nuevos compuestos de antracicli-na

Country Status (16)

Country Link
EP (1) EP0186807B1 (es)
JP (1) JPS61145145A (es)
AT (1) ATE45582T1 (es)
AU (1) AU585918B2 (es)
DE (2) DE3446052A1 (es)
DK (1) DK587185A (es)
ES (1) ES8704506A1 (es)
FI (1) FI80723C (es)
GR (1) GR853020B (es)
HU (1) HU197596B (es)
MX (1) MX7626E (es)
NO (1) NO164038C (es)
NZ (1) NZ214561A (es)
PH (1) PH24107A (es)
PT (1) PT81692B (es)
ZA (1) ZA859607B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3446052A1 (de) * 1984-12-18 1986-07-17 Hoechst Ag, 6230 Frankfurt Anthracyclin-derivate, ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3920062A1 (de) * 1989-06-20 1991-01-10 Hoechst Ag Neue anthracyclin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US5948896A (en) * 1997-08-13 1999-09-07 Gem Pharmaceuticals Processes for preparing 13-deoxy anthracycline derivatives
CN116064288B (zh) * 2022-08-30 2024-04-09 内蒙古农业大学 一株植物解铁、促生浅绛红链霉菌hc7-22及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US436630A (en) * 1890-09-16 Truss-pad
GB2048245B (en) * 1979-04-27 1983-03-16 Erba Farmitalia Biosynthetic antracyline glycoside
JPS5874694A (ja) * 1981-10-29 1983-05-06 Sanraku Inc アントラサイクリン誘導体
DE3446052A1 (de) * 1984-12-18 1986-07-17 Hoechst Ag, 6230 Frankfurt Anthracyclin-derivate, ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
HU197596B (en) 1989-04-28
ATE45582T1 (de) 1989-09-15
EP0186807A2 (de) 1986-07-09
DE3446052A1 (de) 1986-07-17
NO164038B (no) 1990-05-14
EP0186807A3 (en) 1986-11-20
DE3572359D1 (en) 1989-09-21
NO164038C (no) 1990-08-22
JPS61145145A (ja) 1986-07-02
HUT43641A (en) 1987-11-30
PT81692A (de) 1986-01-01
GR853020B (es) 1986-04-15
AU5136285A (en) 1986-07-17
FI80723C (fi) 1990-07-10
DK587185A (da) 1986-06-19
AU585918B2 (en) 1989-06-29
NO854909L (no) 1986-06-19
PH24107A (en) 1990-03-05
ES549951A0 (es) 1987-04-01
NZ214561A (en) 1989-08-29
PT81692B (pt) 1988-04-21
FI854978A (fi) 1986-06-19
ZA859607B (en) 1986-08-27
MX7626E (es) 1990-03-29
FI80723B (fi) 1990-03-30
FI854978A0 (fi) 1985-12-16
DK587185D0 (da) 1985-12-17
EP0186807B1 (de) 1989-08-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970203