AU589145B2 - Urdamycins, a process and streptomyces strain for their preparation, and their use - Google Patents

Urdamycins, a process and streptomyces strain for their preparation, and their use

Info

Publication number
AU589145B2
AU589145B2 AU49975/85A AU4997585A AU589145B2 AU 589145 B2 AU589145 B2 AU 589145B2 AU 49975/85 A AU49975/85 A AU 49975/85A AU 4997585 A AU4997585 A AU 4997585A AU 589145 B2 AU589145 B2 AU 589145B2
Authority
AU
Australia
Prior art keywords
urdamycins
preparation
streptomyces strain
streptomyces
contracting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU49975/85A
Other versions
AU4997585A (en
Inventor
Hannelore Drautz
Peter G. Jones
Erich F. Paulus
Jurgen Rohr
George M. Sheldrick
Hans Zahner
Axel Zeeck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of AU4997585A publication Critical patent/AU4997585A/en
Application granted granted Critical
Publication of AU589145B2 publication Critical patent/AU589145B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/244—Anthraquinone radicals, e.g. sennosides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

1. Claims (for the Contracting States : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE) Urdamycin A of the formula I see diagramm : EP0182208,P18,F2 1. Claims (for the Contracting State AT) A process for the preparation of a compound with an antibiotic action by aerobic fermentation of Streptomyces, which comprises a) fermenting the strain Streptomyces fradiae DSM 3093 and b) extracting the urdamycins from the culture medium.
AU49975/85A 1984-11-16 1985-11-15 Urdamycins, a process and streptomyces strain for their preparation, and their use Ceased AU589145B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3441933 1984-11-16
DE19843441933 DE3441933A1 (en) 1984-11-16 1984-11-16 URDAMYCINE, METHOD AND STREPTOMYCETEEN STEM FOR THE PRODUCTION AND USE THEREOF

Publications (2)

Publication Number Publication Date
AU4997585A AU4997585A (en) 1986-05-22
AU589145B2 true AU589145B2 (en) 1989-10-05

Family

ID=6250474

Family Applications (1)

Application Number Title Priority Date Filing Date
AU49975/85A Ceased AU589145B2 (en) 1984-11-16 1985-11-15 Urdamycins, a process and streptomyces strain for their preparation, and their use

Country Status (5)

Country Link
EP (1) EP0182208B1 (en)
JP (1) JPS61122295A (en)
AT (1) ATE48609T1 (en)
AU (1) AU589145B2 (en)
DE (2) DE3441933A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU598293B2 (en) * 1986-08-28 1990-06-21 Hoechst Aktiengesellschaft Urdamycin G and derivatives thereof, a process for their preparation, and their use

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI873698A (en) * 1986-08-28 1988-02-29 Hoechst Ag ACYLDERIVAT AV URDAMYCIN A, DERAS FRAMSTAELLNING OCH ANVAENDNING.
DE3727139A1 (en) * 1986-08-28 1988-03-10 Hoechst Ag ACYL DERIVATIVES OF URDAMYCIN A, THEIR PRODUCTION AND THEIR USE

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU598293B2 (en) * 1986-08-28 1990-06-21 Hoechst Aktiengesellschaft Urdamycin G and derivatives thereof, a process for their preparation, and their use

Also Published As

Publication number Publication date
EP0182208A2 (en) 1986-05-28
AU4997585A (en) 1986-05-22
JPS61122295A (en) 1986-06-10
DE3441933A1 (en) 1986-06-05
EP0182208B1 (en) 1989-12-13
ATE48609T1 (en) 1989-12-15
EP0182208A3 (en) 1986-11-20
DE3574705D1 (en) 1990-01-18

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