ES8704488A1 - Procedimiento para preparar derivados de 3,4-diazol - Google Patents

Procedimiento para preparar derivados de 3,4-diazol

Info

Publication number
ES8704488A1
ES8704488A1 ES554602A ES554602A ES8704488A1 ES 8704488 A1 ES8704488 A1 ES 8704488A1 ES 554602 A ES554602 A ES 554602A ES 554602 A ES554602 A ES 554602A ES 8704488 A1 ES8704488 A1 ES 8704488A1
Authority
ES
Spain
Prior art keywords
compounds
preparation
diazole derivatives
medicines containing
diazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES554602A
Other languages
English (en)
Other versions
ES554602A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Heumann Ludwig and Co GmbH
Original Assignee
Heumann Ludwig and Co GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heumann Ludwig and Co GmbH filed Critical Heumann Ludwig and Co GmbH
Publication of ES8704488A1 publication Critical patent/ES8704488A1/es
Publication of ES554602A0 publication Critical patent/ES554602A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
    • C07D271/113—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C07D285/135—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR DERIVADOS DE 3,4-DIAZOL. CONSISTE EN CICLIZAR UN COMPUESTO DE FORMULA (II) CON UN AGENTE OXIDANTE COMO HIDROPEROXIDO, EN DIOXANO PARA OBTENER DERIVADOS DE 3,4-DIAZOL DE FORMULA (I) Y SUS SALES FISIOLOGICAMENTE ACEPTABLES, SIENDO: R1 Y R2, QUE PUEDEN SER IGUALES O DIFERENTES, H, ALQUILO C 1 A 10 LINEAL, CICLOALQUILO C 5 A 6, AMINO, ALQUIL C 1 A 3 O DI-(ALQUIL C 1 A 3)-AMINO; A ES UN GRUPO (CH2)N; X ES UN ATOMO DE AZUFRE; Y R3 Y R4 SON ALQUILO DE C 1 A 6, CICLOALQUILO C 5 A 6, HALOGENO Y OTROS. TIENEN APLICACIONES FARMACEUTICAS COMO AGENTES ANTIULCEROSOS.
ES554602A 1984-11-09 1986-04-30 Procedimiento para preparar derivados de 3,4-diazol Expired ES8704488A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843441086 DE3441086A1 (de) 1984-11-09 1984-11-09 3,4-diazolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
ES8704488A1 true ES8704488A1 (es) 1987-04-16
ES554602A0 ES554602A0 (es) 1987-04-16

Family

ID=6249961

Family Applications (4)

Application Number Title Priority Date Filing Date
ES548289A Expired ES8609315A1 (es) 1984-11-09 1985-10-28 Procedimiento para preparar derivados de 3,4 diazol
ES554603A Expired ES8704489A1 (es) 1984-11-09 1986-04-30 Procedimiento para preparar derivados de 3, 4-diazol
ES554601A Expired ES8704487A1 (es) 1984-11-09 1986-04-30 Procedimiento para preparar derivados de 3,4-diazol
ES554602A Expired ES8704488A1 (es) 1984-11-09 1986-04-30 Procedimiento para preparar derivados de 3,4-diazol

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES548289A Expired ES8609315A1 (es) 1984-11-09 1985-10-28 Procedimiento para preparar derivados de 3,4 diazol
ES554603A Expired ES8704489A1 (es) 1984-11-09 1986-04-30 Procedimiento para preparar derivados de 3, 4-diazol
ES554601A Expired ES8704487A1 (es) 1984-11-09 1986-04-30 Procedimiento para preparar derivados de 3,4-diazol

Country Status (15)

Country Link
US (1) US4727081A (es)
EP (1) EP0180754A3 (es)
JP (1) JPS61115074A (es)
KR (1) KR860004040A (es)
AU (1) AU575441B2 (es)
DE (1) DE3441086A1 (es)
DK (1) DK512185A (es)
ES (4) ES8609315A1 (es)
GR (1) GR852687B (es)
HU (1) HU194197B (es)
IL (1) IL76818A (es)
NZ (1) NZ214097A (es)
PT (1) PT81427B (es)
YU (1) YU173585A (es)
ZA (1) ZA858194B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3513184A1 (de) * 1985-04-12 1986-10-16 Ludwig Heumann & Co GmbH, 8500 Nürnberg 1,3,4-thiadiazolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
CN101863852B (zh) * 2010-06-29 2011-09-21 沈阳航空航天大学 含1,3,4-噁二唑杂环结构芳香二元胺及其制备方法
WO2022034121A1 (en) 2020-08-11 2022-02-17 Université De Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5775976A (en) * 1980-08-27 1982-05-12 Glaxo Group Ltd Novel heterocyclic derivative, manufacture and medicinal composition containing same
JPS59196879A (ja) * 1983-04-08 1984-11-08 Wakamoto Pharmaceut Co Ltd 新規な１，３，４−チアジアゾ−ル誘導体
JPS6067474A (ja) * 1983-09-24 1985-04-17 Wakamoto Pharmaceut Co Ltd 新規な１，３，４−チアジアゾ−ル誘導体及びそれを有効成分とする抗潰瘍剤
JPS60255756A (ja) * 1984-06-01 1985-12-17 Ikeda Mohandou:Kk アミノアルキルフエノキシ誘導体

Also Published As

Publication number Publication date
IL76818A0 (en) 1986-02-28
PT81427B (de) 1987-04-09
ES8609315A1 (es) 1986-09-01
AU575441B2 (en) 1988-07-28
EP0180754A3 (de) 1987-02-25
DK512185A (da) 1986-05-10
ES554603A0 (es) 1987-04-16
ES548289A0 (es) 1986-09-01
ZA858194B (en) 1986-06-25
HUT40427A (en) 1986-12-28
GR852687B (es) 1986-03-11
NZ214097A (en) 1988-08-30
ES8704487A1 (es) 1987-04-16
EP0180754A2 (de) 1986-05-14
ES8704489A1 (es) 1987-04-16
HU194197B (en) 1988-01-28
US4727081A (en) 1988-02-23
PT81427A (de) 1985-12-01
ES554601A0 (es) 1987-04-16
AU4933385A (en) 1986-05-15
KR860004040A (ko) 1986-06-16
JPS61115074A (ja) 1986-06-02
DK512185D0 (da) 1985-11-06
DE3441086A1 (de) 1986-05-15
YU173585A (en) 1988-04-30
IL76818A (en) 1990-06-10
ES554602A0 (es) 1987-04-16

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