ES8701712A1 - Un procedimiento para la preparacion de una forma polimorfo i de una sal de monoetanolamina - Google Patents
Un procedimiento para la preparacion de una forma polimorfo i de una sal de monoetanolaminaInfo
- Publication number
- ES8701712A1 ES8701712A1 ES548878A ES548878A ES8701712A1 ES 8701712 A1 ES8701712 A1 ES 8701712A1 ES 548878 A ES548878 A ES 548878A ES 548878 A ES548878 A ES 548878A ES 8701712 A1 ES8701712 A1 ES 8701712A1
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- preparation
- polymorph
- monoethanolamine salt
- polymorphic form
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002169 ethanolamines Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 230000032683 aging Effects 0.000 abstract 2
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 abstract 1
- PGBYMPJXTSIZEC-UHFFFAOYSA-N 4-hydroxy-2-methyl-n-pyridin-2-yl-1,2-benzothiazine-3-carboxamide Chemical compound CN1SC2=CC=CC=C2C(O)=C1C(=O)NC1=CC=CC=N1 PGBYMPJXTSIZEC-UHFFFAOYSA-N 0.000 abstract 1
- 230000002456 anti-arthritic effect Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 239000000155 melt Substances 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 239000003586 protic polar solvent Substances 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16L—PIPES; JOINTS OR FITTINGS FOR PIPES; SUPPORTS FOR PIPES, CABLES OR PROTECTIVE TUBING; MEANS FOR THERMAL INSULATION IN GENERAL
- F16L57/00—Protection of pipes or objects of similar shape against external or internal damage or wear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Mechanical Engineering (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cosmetics (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/672,028 US4582831A (en) | 1984-11-16 | 1984-11-16 | Anti-inflammatory polymorphic monoethanolamine salt of N-(2-pyridyl)-2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide compound, composition, and method of use therefor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8701712A1 true ES8701712A1 (es) | 1986-12-01 |
| ES548878A0 ES548878A0 (es) | 1986-12-01 |
Family
ID=24696846
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES548878A Expired ES8701712A1 (es) | 1984-11-16 | 1985-11-14 | Un procedimiento para la preparacion de una forma polimorfo i de una sal de monoetanolamina |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US4582831A (forum.php) |
| EP (1) | EP0182572B1 (forum.php) |
| JP (1) | JPS61122284A (forum.php) |
| KR (1) | KR870000291B1 (forum.php) |
| CN (1) | CN1004001B (forum.php) |
| AT (1) | ATE50257T1 (forum.php) |
| AU (1) | AU556378B2 (forum.php) |
| CA (1) | CA1209572A (forum.php) |
| DD (1) | DD242405A5 (forum.php) |
| DE (1) | DE3575925D1 (forum.php) |
| DK (1) | DK171726B1 (forum.php) |
| EG (1) | EG17621A (forum.php) |
| ES (1) | ES8701712A1 (forum.php) |
| FI (1) | FI82045C (forum.php) |
| GR (1) | GR852772B (forum.php) |
| HU (1) | HU197899B (forum.php) |
| IE (1) | IE58288B1 (forum.php) |
| IL (1) | IL77051A (forum.php) |
| IN (1) | IN164207B (forum.php) |
| MY (1) | MY101984A (forum.php) |
| NO (1) | NO854574L (forum.php) |
| NZ (1) | NZ214201A (forum.php) |
| PH (1) | PH21322A (forum.php) |
| PL (1) | PL149466B1 (forum.php) |
| PT (1) | PT81490B (forum.php) |
| SU (1) | SU1491339A3 (forum.php) |
| YU (1) | YU44019B (forum.php) |
| ZA (1) | ZA858773B (forum.php) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5436241A (en) * | 1994-01-14 | 1995-07-25 | Bristol-Myers Squibb Company | Topical anti-inflammatory compositions containing piroxicam |
| US20030068829A1 (en) * | 2001-06-25 | 2003-04-10 | Symyx Technologies, Inc. | High throughput crystallographic screening of materials |
| AR040083A1 (es) * | 2002-05-22 | 2005-03-16 | Smithkline Beecham Corp | Compuesto bis-(monoetanolamina) del acido 3'-[(2z)-[1-(3,4-dimetilfenil) -1,5-dihidro-3-metil-5-oxo-4h-pirazol-4-iliden] hidrazino] -2'-hidroxi-[1,1'-bifenil]-3-carboxilico, procedimiento para prepararlo, composicion farmaceutica que lo comprende, procedimiento para preparar dicha composicion farmac |
| ECSP077628A (es) * | 2007-05-03 | 2008-12-30 | Smithkline Beechman Corp | Nueva composición farmacéutica |
| EP2434894B1 (en) | 2009-05-29 | 2016-08-31 | Novartis AG | Methods of administration of thrombopoietin agonist compounds |
| ES2553114T3 (es) * | 2009-07-29 | 2015-12-04 | Nerviano Medical Sciences S.R.L. | Sales de inhibidor de plk |
| GB0914287D0 (en) * | 2009-08-14 | 2009-09-30 | Pci Biotech As | Compositions |
| JP7525254B2 (ja) * | 2019-11-14 | 2024-07-30 | ミヨシ油脂株式会社 | 有機アンモニウム塩とそれを用いた生体試料処理剤 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3591584A (en) * | 1968-08-27 | 1971-07-06 | Pfizer | Benzothiazine dioxides |
| US4434164A (en) * | 1981-06-01 | 1984-02-28 | Pfizer Inc. | Crystalline benzothiazine dioxide salts |
| IN160683B (forum.php) * | 1981-06-01 | 1987-07-25 | Pfizer | |
| RO88420A (ro) * | 1983-04-25 | 1986-01-30 | Pfizer Inc,Us | Procedeu pentru prepararea unor saruri bazice de piroxican depuse pe suporturi farmaceutice |
-
1984
- 1984-11-16 US US06/672,028 patent/US4582831A/en not_active Expired - Lifetime
-
1985
- 1985-10-16 IN IN866/DEL/85A patent/IN164207B/en unknown
- 1985-11-11 EP EP85308190A patent/EP0182572B1/en not_active Expired - Lifetime
- 1985-11-11 AT AT85308190T patent/ATE50257T1/de not_active IP Right Cessation
- 1985-11-11 DE DE8585308190T patent/DE3575925D1/de not_active Expired - Lifetime
- 1985-11-14 ES ES548878A patent/ES8701712A1/es not_active Expired
- 1985-11-14 IL IL77051A patent/IL77051A/xx not_active IP Right Cessation
- 1985-11-14 PL PL1985256259A patent/PL149466B1/pl unknown
- 1985-11-14 CN CN85108245.9A patent/CN1004001B/zh not_active Expired
- 1985-11-14 PT PT81490A patent/PT81490B/pt not_active IP Right Cessation
- 1985-11-14 CA CA000495317A patent/CA1209572A/en not_active Expired
- 1985-11-14 NZ NZ214201A patent/NZ214201A/xx unknown
- 1985-11-14 YU YU1785/85A patent/YU44019B/xx unknown
- 1985-11-14 DD DD85282869A patent/DD242405A5/de not_active IP Right Cessation
- 1985-11-15 PH PH33058A patent/PH21322A/en unknown
- 1985-11-15 FI FI854512A patent/FI82045C/fi not_active IP Right Cessation
- 1985-11-15 AU AU49950/85A patent/AU556378B2/en not_active Ceased
- 1985-11-15 IE IE285285A patent/IE58288B1/en not_active IP Right Cessation
- 1985-11-15 ZA ZA858773A patent/ZA858773B/xx unknown
- 1985-11-15 SU SU853982430A patent/SU1491339A3/ru active
- 1985-11-15 DK DK527585A patent/DK171726B1/da not_active IP Right Cessation
- 1985-11-15 NO NO854574A patent/NO854574L/no unknown
- 1985-11-15 JP JP60256495A patent/JPS61122284A/ja active Granted
- 1985-11-15 GR GR852772A patent/GR852772B/el unknown
- 1985-11-15 HU HU854374A patent/HU197899B/hu not_active IP Right Cessation
- 1985-11-16 KR KR1019850008577A patent/KR870000291B1/ko not_active Expired
- 1985-11-17 EG EG730/85A patent/EG17621A/xx active
-
1987
- 1987-08-14 MY MYPI87001339A patent/MY101984A/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20040925 |