ES8609229A1 - Un procedimiento para la preparacion de alquilsulfonamidofe-nilalquilaminas - Google Patents

Un procedimiento para la preparacion de alquilsulfonamidofe-nilalquilaminas

Info

Publication number
ES8609229A1
ES8609229A1 ES547840A ES547840A ES8609229A1 ES 8609229 A1 ES8609229 A1 ES 8609229A1 ES 547840 A ES547840 A ES 547840A ES 547840 A ES547840 A ES 547840A ES 8609229 A1 ES8609229 A1 ES 8609229A1
Authority
ES
Spain
Prior art keywords
alkylsulfonamidophenylalkylamines
relates
present
new class
oral bioavailability
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES547840A
Other languages
English (en)
Spanish (es)
Other versions
ES547840A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES547840A0 publication Critical patent/ES547840A0/es
Publication of ES8609229A1 publication Critical patent/ES8609229A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/38—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reaction of ammonia or amines with sulfonic acids, or with esters, anhydrides, or halides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ES547840A 1984-10-15 1985-10-14 Un procedimiento para la preparacion de alquilsulfonamidofe-nilalquilaminas Expired ES8609229A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/660,816 US4569801A (en) 1984-10-15 1984-10-15 Alkylsulfonamidophenylalkylamines

Publications (2)

Publication Number Publication Date
ES547840A0 ES547840A0 (es) 1986-09-01
ES8609229A1 true ES8609229A1 (es) 1986-09-01

Family

ID=24651088

Family Applications (1)

Application Number Title Priority Date Filing Date
ES547840A Expired ES8609229A1 (es) 1984-10-15 1985-10-14 Un procedimiento para la preparacion de alquilsulfonamidofe-nilalquilaminas

Country Status (18)

Country Link
US (1) US4569801A (OSRAM)
EP (1) EP0178874B1 (OSRAM)
JP (1) JPS6197256A (OSRAM)
KR (1) KR880001008B1 (OSRAM)
CN (1) CN1004133B (OSRAM)
AR (1) AR241528A1 (OSRAM)
AT (1) ATE41922T1 (OSRAM)
AU (1) AU586644B2 (OSRAM)
CA (1) CA1291165C (OSRAM)
DK (1) DK164450C (OSRAM)
ES (1) ES8609229A1 (OSRAM)
GR (1) GR852496B (OSRAM)
HU (1) HU195479B (OSRAM)
IL (1) IL76707A0 (OSRAM)
NZ (1) NZ213812A (OSRAM)
PT (1) PT81299B (OSRAM)
SU (1) SU1424730A3 (OSRAM)
ZA (1) ZA857871B (OSRAM)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5155268A (en) * 1984-05-04 1992-10-13 The Upjohn Company Antiarrhythmic N-aminoalkylene alkyl and aryl sulfonamides
GB8609630D0 (en) * 1986-04-19 1986-05-21 Pfizer Ltd Anti-arrhythmia agents
EG18188A (en) * 1986-05-01 1992-09-30 Pfizer Ltd Process for preparation anti-arhythmia agents
GB8706662D0 (en) * 1987-03-20 1987-04-23 Pfizer Ltd Anti-arrhythmia agents
DE3732094A1 (de) * 1987-09-24 1989-04-06 Basf Ag Bispidinderivate als klasse iii-antiarrhythmika
US4906634A (en) * 1988-03-08 1990-03-06 Schering A.G. Novel N-[4-(aminosubstituted)phenyl]methanesulfonamides and their use as cardiovascular agents
ZA892517B (en) * 1988-04-08 1990-12-28 Lilly Co Eli Propanamine derivatives
US5238959A (en) * 1988-04-08 1993-08-24 Eli Lilly And Company 3-phenyloxy-3-phenyl propanamines
US5405997A (en) * 1989-07-25 1995-04-11 The Upjohn Company Antiarrhythmic methanesulfonamides
JPH10505829A (ja) * 1994-09-12 1998-06-09 ファルマシア・アンド・アップジョン・カンパニー 抗不整脈活性を有する４−（４−メタンスルホンアミドフェニル）ブチルアミン誘導体
US5874475A (en) * 1995-12-21 1999-02-23 Pharmacia & Upjohn Company Antiarrhythmic (S)-enantiomers of methanesulfonamides
US6024740A (en) 1997-07-08 2000-02-15 The Regents Of The University Of California Circumferential ablation device assembly
US5971983A (en) * 1997-05-09 1999-10-26 The Regents Of The University Of California Tissue ablation device and method of use
US6012457A (en) * 1997-07-08 2000-01-11 The Regents Of The University Of California Device and method for forming a circumferential conduction block in a pulmonary vein
US6245064B1 (en) 1997-07-08 2001-06-12 Atrionix, Inc. Circumferential ablation device assembly
US6997925B2 (en) * 1997-07-08 2006-02-14 Atrionx, Inc. Tissue ablation device assembly and method for electrically isolating a pulmonary vein ostium from an atrial wall
US6966908B2 (en) 1997-07-08 2005-11-22 Atrionix, Inc. Tissue ablation device assembly and method for electrically isolating a pulmonary vein ostium from an atrial wall
US6164283A (en) * 1997-07-08 2000-12-26 The Regents Of The University Of California Device and method for forming a circumferential conduction block in a pulmonary vein
US6869431B2 (en) 1997-07-08 2005-03-22 Atrionix, Inc. Medical device with sensor cooperating with expandable member
US6652515B1 (en) * 1997-07-08 2003-11-25 Atrionix, Inc. Tissue ablation device assembly and method for electrically isolating a pulmonary vein ostium from an atrial wall
US6514249B1 (en) 1997-07-08 2003-02-04 Atrionix, Inc. Positioning system and method for orienting an ablation element within a pulmonary vein ostium
US6500174B1 (en) 1997-07-08 2002-12-31 Atrionix, Inc. Circumferential ablation device assembly and methods of use and manufacture providing an ablative circumferential band along an expandable member
WO2000010557A1 (fr) * 1998-08-25 2000-03-02 Nippon Shinyaku Co.,Ltd. Preparations solides stabilisees
US6607502B1 (en) 1998-11-25 2003-08-19 Atrionix, Inc. Apparatus and method incorporating an ultrasound transducer onto a delivery member
US6758830B1 (en) 1999-05-11 2004-07-06 Atrionix, Inc. Catheter positioning system
ATE353001T1 (de) 1999-05-11 2007-02-15 Atrionix Inc Ballonverankerungsdraht
AU6321301A (en) 2000-05-16 2001-11-26 Atrionix Inc Apparatus and method incorporating an ultrasound transducer onto a delivery member
ES2240470T3 (es) 2000-06-13 2005-10-16 Atrionix, Inc. Sonda de ablacion quirurgica que permite realizar una lesion circular.
DE60110891T2 (de) 2000-09-08 2006-03-23 Atrionix Inc., Palo Alto Medizinisches gerät mit einem sensor in kooperation mit einem ausdehnbaren teil
US6755822B2 (en) 2001-06-01 2004-06-29 Cryocor, Inc. Device and method for the creation of a circumferential cryogenic lesion in a pulmonary vein
US20040106896A1 (en) * 2002-11-29 2004-06-03 The Regents Of The University Of California System and method for forming a non-ablative cardiac conduction block
US6932804B2 (en) 2003-01-21 2005-08-23 The Regents Of The University Of California System and method for forming a non-ablative cardiac conduction block
JP2005524496A (ja) * 2002-05-08 2005-08-18 ザ リージェンツ オブ ザ ユニヴァーシティー オブ カリフォルニア 非破壊性心伝導ブロック形成用システム及び方法
US6786202B2 (en) * 2002-09-24 2004-09-07 Caterpillar Inc Hydraulic pump circuit
US7317950B2 (en) * 2002-11-16 2008-01-08 The Regents Of The University Of California Cardiac stimulation system with delivery of conductive agent
US7670335B2 (en) 2003-07-21 2010-03-02 Biosense Webster, Inc. Ablation device with spiral array ultrasound transducer
US7247269B2 (en) * 2003-07-21 2007-07-24 Biosense Webster, Inc. Method for making a spiral array ultrasound transducer
MXPA06007624A (es) * 2003-12-31 2007-01-30 Johnson & Johnson Montaje de dispositivo de ablacion circunferencial con dos miembros expansibles.
US20060270900A1 (en) * 2005-05-26 2006-11-30 Chin Albert K Apparatus and methods for performing ablation
US8932208B2 (en) * 2005-05-26 2015-01-13 Maquet Cardiovascular Llc Apparatus and methods for performing minimally-invasive surgical procedures
US20070185479A1 (en) * 2006-02-06 2007-08-09 Liming Lau Methods and devices for performing ablation and assessing efficacy thereof
US20070225697A1 (en) * 2006-03-23 2007-09-27 Ketan Shroff Apparatus and methods for cardiac ablation
US20080039879A1 (en) * 2006-08-09 2008-02-14 Chin Albert K Devices and methods for atrial appendage exclusion
US8728073B2 (en) 2006-10-10 2014-05-20 Biosense Webster, Inc. Multi-region staged inflation balloon
US8512387B2 (en) * 2007-09-07 2013-08-20 Robert S. Fishel Esophageal cooling system for ablation procedures associated with cardiac arrhythmias
EP2209517A4 (en) 2007-10-05 2011-03-30 Maquet Cardiovascular Llc DEVICES AND METHODS FOR MINIMALLY INVASIVE SURGICAL PROCEDURES
US20090209986A1 (en) * 2008-02-15 2009-08-20 Stewart Michael C Devices, Tools and Methods for Atrial Appendage Exclusion

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR152F (OSRAM) * 1962-01-24
US3574741A (en) * 1969-04-14 1971-04-13 Mead Johnson & Co Sulfonamidophenalkylamines
HU173192B (hu) * 1973-08-13 1979-03-28 Fujisawa Pharmaceutical Co Sposob poluchenija novykh proizvodnykh fenilglicina
US4289787A (en) * 1977-12-19 1981-09-15 Eli Lilly And Company Quaternary ammonium antiarrhythmic drugs
US4277501A (en) * 1977-12-19 1981-07-07 Eli Lilly And Company Para-nitrophenylalkylamines and pharmaceutical compositions
DK268579A (da) * 1978-07-03 1980-01-04 Lilly Co Eli Fremgangsmaade til fremstilling af phenetamolaminer
US4336269A (en) * 1979-12-10 1982-06-22 Eli Lilly And Company Para-nitrophenylalkylamines
EP0164865B1 (en) * 1984-05-04 1988-12-21 The Upjohn Company N-(aminoalkylphenyl)sulfonamides their preparation and therapeutic use

Also Published As

Publication number Publication date
US4569801A (en) 1986-02-11
AU586644B2 (en) 1989-07-20
PT81299B (pt) 1988-02-17
CN1004133B (zh) 1989-05-10
DK164450B (da) 1992-06-29
KR880001008B1 (ko) 1988-06-13
ZA857871B (en) 1987-05-27
EP0178874B1 (en) 1989-04-05
ES547840A0 (es) 1986-09-01
AR241528A1 (es) 1992-08-31
HU195479B (en) 1988-05-30
DK468185D0 (da) 1985-10-14
HUT38610A (en) 1986-06-30
NZ213812A (en) 1989-01-06
SU1424730A3 (ru) 1988-09-15
ATE41922T1 (de) 1989-04-15
CA1291165C (en) 1991-10-22
GR852496B (OSRAM) 1986-02-18
AU4855885A (en) 1986-04-24
PT81299A (en) 1985-11-01
KR860003210A (ko) 1986-05-21
EP0178874A1 (en) 1986-04-23
IL76707A0 (en) 1986-02-28
DK468185A (da) 1986-04-16
JPS6197256A (ja) 1986-05-15
CN85107020A (zh) 1986-04-10
DK164450C (da) 1992-11-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303