ES8608888A1 - Una formulacion parenteral endoparasiticida y ectoparasiticida - Google Patents

Una formulacion parenteral endoparasiticida y ectoparasiticida

Info

Publication number
ES8608888A1
ES8608888A1 ES538750A ES538750A ES8608888A1 ES 8608888 A1 ES8608888 A1 ES 8608888A1 ES 538750 A ES538750 A ES 538750A ES 538750 A ES538750 A ES 538750A ES 8608888 A1 ES8608888 A1 ES 8608888A1
Authority
ES
Spain
Prior art keywords
avermectin
milbemycin
antiparasitic
formulation containing
aqueous formulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES538750A
Other languages
English (en)
Other versions
ES538750A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES538750A0 publication Critical patent/ES538750A0/es
Publication of ES8608888A1 publication Critical patent/ES8608888A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

METODO DE PREPARACION DE FORMULACIONES PARENTERALES ENDOPARASITICIDA Y ECTOPARASITICIDA, DE EVERMECTINA O MILBEMICINA, QUE TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE INFECCIONES PARASITARIAS. CONSISTE EN LA DISOLUCION DE UN COMPUESTO DE EVERMECTINA O MILBEMICINA, TAL COMO INVERMECTINA EN UNA MEZCLA DE PROPILENGLICOL Y GLICEROFORMAL, O DE PROPILENGLICOL Y AGUA, MEDIANTE AGITACION, Y A CONTINUACION AJUSTAR LA CONCENTRACION DE LA DISOLUCION, POR ADICION DEL DISOLVENTE ADECUADO, DE MODO QUE EL COMPUESTO ACTIVO SE HALLE EN UNA PROPORCION COMPRENDIDA ENTRE 0,1 Y 20% PESO/VOLUMEN, Y LA RELACION DE GLICEROFORMAL A PROPILENGLICOL SEA 10:90 A 90:10 O, EN SU CASO, LA DE AGUA A PROPILENGLICOL SEA DE 2:95 A 20:80; Y ESTERILIZACION DE LA DISOLUCION POR MEDIOS NO TERMICOS.
ES538750A 1983-12-22 1984-12-18 Una formulacion parenteral endoparasiticida y ectoparasiticida Expired ES8608888A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56414083A 1983-12-22 1983-12-22

Publications (2)

Publication Number Publication Date
ES538750A0 ES538750A0 (es) 1986-07-16
ES8608888A1 true ES8608888A1 (es) 1986-07-16

Family

ID=24253315

Family Applications (1)

Application Number Title Priority Date Filing Date
ES538750A Expired ES8608888A1 (es) 1983-12-22 1984-12-18 Una formulacion parenteral endoparasiticida y ectoparasiticida

Country Status (17)

Country Link
EP (1) EP0146414B1 (es)
JP (1) JPH0623100B2 (es)
KR (1) KR880002366B1 (es)
AT (1) ATE47522T1 (es)
AU (1) AU560864B2 (es)
CA (1) CA1267844A (es)
DE (1) DE3480263D1 (es)
DK (1) DK164772C (es)
ES (1) ES8608888A1 (es)
GR (1) GR81244B (es)
HK (1) HK5091A (es)
IE (1) IE57681B1 (es)
IL (1) IL73800A (es)
NZ (1) NZ210505A (es)
PT (1) PT79656B (es)
SG (1) SG97890G (es)
ZA (1) ZA849841B (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0284176B1 (en) * 1987-01-23 1993-08-25 Pfizer Inc. Process for production of avermectins and cultures therefor
US5075307A (en) * 1987-07-28 1991-12-24 Merck & Co., Inc. Paraherquamide and dihydroparaherquamide as antihelminthic agents
GB8803836D0 (en) * 1988-02-18 1988-03-16 Glaxo Group Ltd Compositions
US6001822A (en) * 1989-04-11 1999-12-14 Pfizer Inc. Antiparasitic formulations
US5169846A (en) * 1989-10-12 1992-12-08 Crooks Michael J Non-aqueous micellar solutions of anthelmintic benzimidazoles, closantel, or phenothiazine, and insect growth regulators
NZ335166A (en) 1999-04-14 2001-11-30 Ashmont Holdings Ltd Anthelmintic composition containing triclabendazole in at least one solvent
GB2275193A (en) * 1993-02-17 1994-08-24 Merck & Co Inc Formulations for the topical delivery of avermectins
PL174488B1 (pl) * 1993-05-10 1998-08-31 Merck & Co Inc Preparat do zwalczania pasożytów zwierząt oraz sposób wytwarzania preparatu do zwalczania pasożytów zwierząt
US5602107A (en) * 1993-05-10 1997-02-11 Merck & Co., Inc. Pour-on formulations consisting of gylcols, glycerides and avermectin compounds
RO115102B1 (ro) * 1993-05-10 1999-11-30 Merck & Co Inc Formulari topice pe baza de avermectina si procedee de preparare a acestora
DE19613972A1 (de) * 1996-04-09 1997-10-16 Bayer Ag Injektionsformulierungen von Avermectinen und Milbemycinen auf Basis von Rizinusöl
DE19638045A1 (de) * 1996-09-18 1998-03-19 Bayer Ag Injektionsformulierungen von Avermectinen und Milbemycinen
US6054140A (en) * 1997-03-21 2000-04-25 Biogenesis S.A. Long acting injectable parasiticidal composition and the process for its preparation
UY25089A1 (es) * 1997-07-10 2000-08-21 Hoechst Roussel Vet Gmbh Vacunas no acuosas
GB9816132D0 (en) * 1998-07-24 1998-09-23 Norbrook Lab Ltd Non-aqueous anthelmintic composition
EP1215964A4 (en) * 1999-09-22 2002-11-05 Ashmont Holdings Ltd POUR-ON COMPOSITION FOR SHEEP
JP2001253824A (ja) * 2000-03-14 2001-09-18 Mitsukazu Matsumoto 局所注射用処方剤
GR1003969B (el) * 2001-02-05 2002-08-14 U��-Pharma ����� ������ ������������ ���������� ���� Σταθερα φαρμακευτικα διαλυματα νιμεσουλιδης.
US20050009762A1 (en) 2003-06-06 2005-01-13 Strobel Michael Albert Application of water and organic solvent soluble ivermectin for topical and oral use
US6627613B2 (en) 2001-07-23 2003-09-30 Michael A. Strobel Application of water and organic solvent soluble ivermectin for topical and oral use
GB2386066A (en) 2002-02-28 2003-09-10 Norbrook Lab Ltd Long-acting parasiticidal composition with improved bioavailability comprising a salicylanilide, a further anti-parasitic compound & a polymeric species
UY27412A1 (es) * 2002-08-12 2003-06-30 Carlson Internat Inc Un nuevo producto para el combate de garrapatas y el proceso para la prepaacinn.
GB0316377D0 (en) 2003-07-12 2003-08-13 Norbrook Lab Ltd Parasiticidal composition
JP4886214B2 (ja) * 2005-05-24 2012-02-29 日本パワーファスニング株式会社 石膏ボード締結用の２条式木ねじ
PT2331068T (pt) 2008-10-08 2017-03-13 Zoetis Services Llc Composições anti-helmínticas de benzimidazol
JP5607114B2 (ja) 2012-06-26 2014-10-15 株式会社トープラ タッピンねじ
JP2024516912A (ja) 2021-05-14 2024-04-17 シンジェンタ クロップ プロテクション アクチェンゲゼルシャフト 昆虫、ダニ目及び線虫有害生物の防除
WO2022268815A1 (en) 2021-06-24 2022-12-29 Syngenta Crop Protection Ag Insect, acarina and nematode pest control

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4144352A (en) * 1977-12-19 1979-03-13 Merck & Co., Inc. Milbemycin compounds as anthelmintic agents
US4130651A (en) * 1978-03-31 1978-12-19 American Cyanamid Company Butamisole injectable formulations having improved margin of safety in dogs
NZ197796A (en) * 1980-08-04 1984-11-09 Merck & Co Inc Stabilised aqueous formulations containing ivermectin
US4430329A (en) * 1982-05-17 1984-02-07 Merck & Co., Inc. Synergistic treatment of adult canine heartworm with thiacetarsamide and ivermectin

Also Published As

Publication number Publication date
EP0146414A3 (en) 1986-12-10
PT79656B (en) 1987-01-16
DK164772B (da) 1992-08-17
PT79656A (en) 1985-01-01
DK619784D0 (da) 1984-12-21
KR880002366B1 (ko) 1988-11-03
HK5091A (en) 1991-01-18
NZ210505A (en) 1988-06-30
IL73800A (en) 1987-11-30
IL73800A0 (en) 1985-03-31
AU560864B2 (en) 1987-04-16
ES538750A0 (es) 1986-07-16
GR81244B (en) 1985-04-16
EP0146414A2 (en) 1985-06-26
IE57681B1 (en) 1993-02-24
KR850004391A (ko) 1985-07-15
DK164772C (da) 1993-01-04
SG97890G (en) 1991-02-14
EP0146414B1 (en) 1989-10-25
JPS60169415A (ja) 1985-09-02
ATE47522T1 (de) 1989-11-15
DK619784A (da) 1985-06-23
CA1267844A (en) 1990-04-17
AU3702484A (en) 1985-07-04
DE3480263D1 (en) 1989-11-30
JPH0623100B2 (ja) 1994-03-30
IE843221L (en) 1985-06-22
ZA849841B (en) 1986-07-30

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20060408