IT8323956A0 - Antibiotici macrolidi e preparazione orale stabile di procedimento di stabilizzazione. - Google Patents

Antibiotici macrolidi e preparazione orale stabile di procedimento di stabilizzazione.

Info

Publication number
IT8323956A0
IT8323956A0 IT8323956A IT2395683A IT8323956A0 IT 8323956 A0 IT8323956 A0 IT 8323956A0 IT 8323956 A IT8323956 A IT 8323956A IT 2395683 A IT2395683 A IT 2395683A IT 8323956 A0 IT8323956 A0 IT 8323956A0
Authority
IT
Italy
Prior art keywords
oral preparation
macrolide antibiotics
stable oral
stabilization procedure
stabilization
Prior art date
Application number
IT8323956A
Other languages
English (en)
Other versions
IT1169476B (it
Inventor
Masataka Morishita
Masaru Ono
Yukio Sumita
Original Assignee
Toyo Jozo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyo Jozo Kk filed Critical Toyo Jozo Kk
Publication of IT8323956A0 publication Critical patent/IT8323956A0/it
Application granted granted Critical
Publication of IT1169476B publication Critical patent/IT1169476B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IT23956/83A 1982-12-04 1983-11-30 Preparazione orale stabile di antibiotici macrolidi e procedimento di stabilizzazione IT1169476B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57212942A JPS59104326A (ja) 1982-12-04 1982-12-04 マクロライド抗生物質の安定な経口用製剤および安定化法

Publications (2)

Publication Number Publication Date
IT8323956A0 true IT8323956A0 (it) 1983-11-30
IT1169476B IT1169476B (it) 1987-05-27

Family

ID=16630843

Family Applications (1)

Application Number Title Priority Date Filing Date
IT23956/83A IT1169476B (it) 1982-12-04 1983-11-30 Preparazione orale stabile di antibiotici macrolidi e procedimento di stabilizzazione

Country Status (5)

Country Link
US (1) US4716153A (it)
JP (1) JPS59104326A (it)
FR (1) FR2541287B1 (it)
GB (1) GB2132086B (it)
IT (1) IT1169476B (it)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3524572A1 (de) * 1985-07-10 1987-01-15 Thomae Gmbh Dr K Feste arzneimittelformen zur peroralen anwendung enthaltend 9-deoxo-11-deoxy-9,11-(imino(2-(2-methoxyethoxy)ethyliden)-oxy)-(9s)-erythromycin und verfahren zu ihrer herstellung
IT1222309B (it) * 1987-07-08 1990-09-05 Menarini Sas Utilizzazione di forme farmaceutiche per uso topico contenenti miocamicina per la terapia delle infezione da germi sensibili alla miocamicina stessa
US4877615A (en) * 1988-09-23 1989-10-31 Microlife Technics, Inc. Antifungal product
IL115742A (en) * 1994-10-26 2000-06-01 Novartis Ag Pharmaceutical compositions comprising a difficultly soluble active agent a hydrophilic phase a lipophilic phase and a surfactant
US7205279B2 (en) * 1995-10-25 2007-04-17 Novartis Ag Pharmaceutical compositions
DE4444051A1 (de) * 1994-12-10 1996-06-13 Rhone Poulenc Rorer Gmbh Pharmazeutische, oral anwendbare Zubereitung
KR20030011797A (ko) * 2000-03-28 2003-02-11 바이오케미 게젤샤프트 엠베하 맛이 차폐된 과립형 입자
US6514537B1 (en) 2000-06-02 2003-02-04 Cumberland Swan Holdings, Inc. Magnesium citrate solution
ITMI20021725A1 (it) * 2002-08-01 2002-10-31 Zambon Spa Composizioni farmaceutiche ad attivita' antibiotica.
GB0230034D0 (en) * 2002-12-23 2003-01-29 Biochemie Gmbh Organic compounds
US7803817B2 (en) * 2005-05-11 2010-09-28 Vecta, Ltd. Composition and methods for inhibiting gastric acid secretion
US7981908B2 (en) * 2005-05-11 2011-07-19 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion
CN101472613A (zh) * 2006-04-12 2009-07-01 R·L·亚历山大 包含丙酮酸烷基酯的组合物及其应用
RU2467747C2 (ru) * 2006-07-25 2012-11-27 Векта Лтд. Композиции и способы для ингибирования секреции желудочной кислоты с использованием производных малых дикарбоновых кислот в сочетании с ppi
CN101917850B (zh) 2007-10-25 2016-01-13 森普拉制药公司 大环内酯类抗菌剂的制备方法
RS55118B1 (sr) 2010-02-17 2016-12-30 Veloxis Pharmaceuticals As Stabilizovana takrolimus kompozicija
US8604078B2 (en) * 2011-04-06 2013-12-10 Carlos Picornell Darder Fosfomycin pharmaceutical composition
SG11201405895UA (en) * 2012-03-27 2014-10-30 Cempra Pharmaceuticals Inc Parenteral formulations for administering macrolide antibiotics

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1375986A (en) * 1966-04-25 1974-12-04 Schmid Inc Julius Polyenic macrolide composition
US4064230A (en) * 1966-04-25 1977-12-20 Schmid Laboratories, Inc. Polyenic macrolide compositions
US3891752A (en) * 1966-04-25 1975-06-24 Schmid Lab Polyenic macrolide compositions and methods of use
GB1380741A (en) * 1971-02-05 1975-01-15 Squibb & Sons Inc Antibiotic compositions and their preparation
GB1322306A (en) * 1971-04-15 1973-07-04 Meiji Seika Co Stabilized antibiotic preparation and manufacturing process therefor
JPS531328B2 (it) * 1971-12-13 1978-01-18
US4137307A (en) * 1973-11-15 1979-01-30 The Green Cross Corporation Process for preparing haptoglobin aqueous solution using strong anion exchanger
US4102999A (en) * 1975-02-10 1978-07-25 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Process for producing stable macromomycin powder
US4127647A (en) * 1975-04-08 1978-11-28 Meiji Seika Kaisha, Ltd. Process for preparation of stable amorphous macrolide antibiotic solids
GB1550359A (en) * 1975-08-07 1979-08-15 Beecham Group Ltd Antibiotic compositions for oral administration
GB1511852A (en) * 1975-09-11 1978-05-24 Beecham Group Ltd Reconstitutable powders
AU514992B2 (en) * 1976-06-18 1981-03-12 Rockwell International Corporation Flexible tube, axial flow valve
ZA786259B (en) * 1977-11-09 1979-10-31 Procter & Gamble Therapeutic composition
JPS54115389A (en) * 1978-02-27 1979-09-07 Meiji Seika Kaisha Ltd Novel macrolide antibiotic derivative and its preparation
AU529422B2 (en) * 1978-10-20 1983-06-09 Eli Lilly And Company Stable erythromycin solution
ZA795508B (en) * 1978-10-23 1981-05-27 Schering Corp Derivatives of polyene macrolide antibiotics containing an amino sugar moiety, process for the preparation thereof, and pharmaceutical compositions containing them
US4338335A (en) * 1980-02-05 1982-07-06 Merck & Co., Inc. Vaccine stabilizer containing L-glutamic acid and L-arginine
JPS56135418A (en) * 1980-03-27 1981-10-22 Green Cross Corp:The Heat treatment of aqueous solution containing 8 factor of coagulation of blood derived from human
US4340582A (en) * 1981-01-15 1982-07-20 Abbott Laboratories Erythromycin base tablets

Also Published As

Publication number Publication date
GB8331772D0 (en) 1984-01-04
GB2132086A (en) 1984-07-04
JPS59104326A (ja) 1984-06-16
IT1169476B (it) 1987-05-27
GB2132086B (en) 1986-05-21
FR2541287A1 (fr) 1984-08-24
FR2541287B1 (fr) 1987-08-07
US4716153A (en) 1987-12-29
JPS6411007B2 (it) 1989-02-23

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971129