JPS54115389A - Novel macrolide antibiotic derivative and its preparation - Google Patents
Novel macrolide antibiotic derivative and its preparationInfo
- Publication number
- JPS54115389A JPS54115389A JP2101178A JP2101178A JPS54115389A JP S54115389 A JPS54115389 A JP S54115389A JP 2101178 A JP2101178 A JP 2101178A JP 2101178 A JP2101178 A JP 2101178A JP S54115389 A JPS54115389 A JP S54115389A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- macrolide antibiotic
- preparation
- antibiotic derivative
- acetyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A macrolide antibiotic derivative of formula I: (R1 is 2W5C alkanoyl group; R2 is acetyl or propionyl group). EXANPLE:Substance 9-deoxy-10,12-dediono-9,11-dieno-13-hydroxy-3"-acetyl-S,F- 837
USE: Antibacterials for men and animals or intermediates for its synthesis.
PROCESS: A compound of formula II: (R3 is 2W5C alkanoyl group) is dissolved in an acidic aqueous medium of PH 0.2W4, preferably 1W2C, and left to stand at 40°C or below or stirred, and the reaction mixture is adjusted to pH 7.5W9 with sodium bicorbonate, NH3. etc. The deposited crystal is filtered to give the compound of formula I.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2101178A JPS54115389A (en) | 1978-02-27 | 1978-02-27 | Novel macrolide antibiotic derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2101178A JPS54115389A (en) | 1978-02-27 | 1978-02-27 | Novel macrolide antibiotic derivative and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS54115389A true JPS54115389A (en) | 1979-09-07 |
Family
ID=12043113
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2101178A Pending JPS54115389A (en) | 1978-02-27 | 1978-02-27 | Novel macrolide antibiotic derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS54115389A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4716153A (en) * | 1982-12-04 | 1987-12-29 | Toyo Jozo Company, Ltd. | Stable oral preparation of macrolide antibiotics and method for stabilizing the same |
-
1978
- 1978-02-27 JP JP2101178A patent/JPS54115389A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4716153A (en) * | 1982-12-04 | 1987-12-29 | Toyo Jozo Company, Ltd. | Stable oral preparation of macrolide antibiotics and method for stabilizing the same |
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