JPS54115389A - Novel macrolide antibiotic derivative and its preparation - Google Patents

Novel macrolide antibiotic derivative and its preparation

Info

Publication number
JPS54115389A
JPS54115389A JP2101178A JP2101178A JPS54115389A JP S54115389 A JPS54115389 A JP S54115389A JP 2101178 A JP2101178 A JP 2101178A JP 2101178 A JP2101178 A JP 2101178A JP S54115389 A JPS54115389 A JP S54115389A
Authority
JP
Japan
Prior art keywords
formula
macrolide antibiotic
preparation
antibiotic derivative
acetyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2101178A
Other languages
Japanese (ja)
Inventor
Tomoko Shomura
Shigeharu Inoue
Koshiro Umemura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meiji Seika Kaisha Ltd
Original Assignee
Meiji Seika Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha Ltd filed Critical Meiji Seika Kaisha Ltd
Priority to JP2101178A priority Critical patent/JPS54115389A/en
Publication of JPS54115389A publication Critical patent/JPS54115389A/en
Pending legal-status Critical Current

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  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A macrolide antibiotic derivative of formula I: (R1 is 2W5C alkanoyl group; R2 is acetyl or propionyl group). EXANPLE:Substance 9-deoxy-10,12-dediono-9,11-dieno-13-hydroxy-3"-acetyl-S,F- 837
USE: Antibacterials for men and animals or intermediates for its synthesis.
PROCESS: A compound of formula II: (R3 is 2W5C alkanoyl group) is dissolved in an acidic aqueous medium of PH 0.2W4, preferably 1W2C, and left to stand at 40°C or below or stirred, and the reaction mixture is adjusted to pH 7.5W9 with sodium bicorbonate, NH3. etc. The deposited crystal is filtered to give the compound of formula I.
COPYRIGHT: (C)1979,JPO&Japio
JP2101178A 1978-02-27 1978-02-27 Novel macrolide antibiotic derivative and its preparation Pending JPS54115389A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2101178A JPS54115389A (en) 1978-02-27 1978-02-27 Novel macrolide antibiotic derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2101178A JPS54115389A (en) 1978-02-27 1978-02-27 Novel macrolide antibiotic derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS54115389A true JPS54115389A (en) 1979-09-07

Family

ID=12043113

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2101178A Pending JPS54115389A (en) 1978-02-27 1978-02-27 Novel macrolide antibiotic derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS54115389A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4716153A (en) * 1982-12-04 1987-12-29 Toyo Jozo Company, Ltd. Stable oral preparation of macrolide antibiotics and method for stabilizing the same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4716153A (en) * 1982-12-04 1987-12-29 Toyo Jozo Company, Ltd. Stable oral preparation of macrolide antibiotics and method for stabilizing the same

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