ES8608866A1 - Una composicion farmaceutica reblandecida por el calor ade- cuada para el relleno de capsulas - Google Patents

Una composicion farmaceutica reblandecida por el calor ade- cuada para el relleno de capsulas

Info

Publication number
ES8608866A1
ES8608866A1 ES546545A ES546545A ES8608866A1 ES 8608866 A1 ES8608866 A1 ES 8608866A1 ES 546545 A ES546545 A ES 546545A ES 546545 A ES546545 A ES 546545A ES 8608866 A1 ES8608866 A1 ES 8608866A1
Authority
ES
Spain
Prior art keywords
hot melt
antihistamine
antihistamine formulations
formulations
hard
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES546545A
Other languages
English (en)
Other versions
ES546545A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Publication of ES546545A0 publication Critical patent/ES546545A0/es
Publication of ES8608866A1 publication Critical patent/ES8608866A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

METODO DE PREPARACION DE COMPOSICIONES FARMACEUTICAS DE TERFENADINA ABLANDABLE POR EL CALOR, CON LA QUE SE PUEDEN RELLENAR CAPSULAS. COMPRENDE EL ABLANDAMIENTO O FUSION DE POLIETILENGLICOL DE PESO MOLECULAR MEDIO 3350, A UNA TEMPERATURA COMPRENDIDA ENTRE 60JC Y 80JC; SEGUIDA DE LA ADICION DE TERFENADINA Y CERA DE PARAFINA AL POLIETILENGLICOL FUNDIDO, MIENTRAS SE AGITA PARA FORMAR UNA DISPERSION UNIFORME; Y, FINALMENTE, ENFRIAMIENTO DEL PRODUCTO HOMOGENEIZADO. LA COMPOSICION ESTA CONSTITUIDA POR 8 A 28 PARTES DE TERFENADINA O UNA DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, 5 PARTES DE CERA Y 68 A 92 PARTES DE POLIETILENGLICOL. ESTAS COMPOSICIONES TIENEN APLICACIONES COMO ANTIHISTAMINICOS Y ANTIALERGICOS.
ES546545A 1984-08-30 1985-08-29 Una composicion farmaceutica reblandecida por el calor ade- cuada para el relleno de capsulas Expired ES8608866A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64617984A 1984-08-30 1984-08-30

Publications (2)

Publication Number Publication Date
ES546545A0 ES546545A0 (es) 1986-07-16
ES8608866A1 true ES8608866A1 (es) 1986-07-16

Family

ID=24592083

Family Applications (1)

Application Number Title Priority Date Filing Date
ES546545A Expired ES8608866A1 (es) 1984-08-30 1985-08-29 Una composicion farmaceutica reblandecida por el calor ade- cuada para el relleno de capsulas

Country Status (19)

Country Link
EP (1) EP0173293B1 (es)
JP (1) JPH0621068B2 (es)
KR (1) KR920007832B1 (es)
AR (1) AR242341A1 (es)
AT (1) ATE68972T1 (es)
AU (1) AU579177B2 (es)
CA (1) CA1250526A (es)
DE (1) DE3584557D1 (es)
DK (1) DK164642C (es)
ES (1) ES8608866A1 (es)
FI (1) FI87992C (es)
GR (1) GR852078B (es)
HU (1) HU195421B (es)
IE (1) IE58080B1 (es)
IL (1) IL76237A (es)
NZ (1) NZ213248A (es)
PH (1) PH21083A (es)
PT (1) PT81028B (es)
ZA (1) ZA856482B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8507779D0 (en) * 1985-03-26 1985-05-01 Fujisawa Pharmaceutical Co Drug carrier
AR240018A1 (es) * 1987-10-07 1990-01-31 Merrell Pharma Inc Procedimiento para preparar una composicion que comprende derivados de piperidinoalcanol.
ZA90341B (en) * 1989-01-23 1990-10-31 Merrell Dow Pharma Liquid pharmaceutical composition for piperidinoalkanol derivatives
DE69027267T2 (de) * 1989-09-07 1996-10-17 Fuji Photo Film Co Ltd Verfahren zur Verarbeitung eines farbfotografischen Silberhalogenidmaterials
US5270064A (en) * 1991-04-12 1993-12-14 Avian Allure Encapsulated food product with readily removable capsule
US5455045A (en) * 1993-05-13 1995-10-03 Syntex (U.S.A.) Inc. High dose formulations
GB2281697A (en) * 1993-09-14 1995-03-15 Euro Celtique Sa Laxative compositions in capsules
AU701042B2 (en) * 1995-02-28 1999-01-21 Aventisub Llc Pharmaceutical composition for piperidinoalkanol compounds
US5574045A (en) * 1995-06-06 1996-11-12 Hoechst Marion Roussel, Inc. Oral pharmaceutical composition of piperidinoalkanol compounds in solution form
DK0998272T3 (da) * 1997-08-26 2003-08-25 Aventis Pharma Inc Farmaceutisk præparat til kombinationen piperidinoalkanoldekongestivum
AUPP279698A0 (en) * 1998-04-03 1998-04-30 Sunscape Developments Limited Sustained release formulation
FR2838349B1 (fr) * 2002-04-15 2004-06-25 Laurence Paris Compositions liquides pour capsules molle a liberation prolongee et leur procede de fabrication
EP1829541A1 (en) * 2002-12-17 2007-09-05 Abbott GmbH & Co. KG Formulation comprising fenofibric acid or a physiologically acceptable salt thereof
WO2004054568A1 (en) * 2002-12-17 2004-07-01 Abbott Gmbh & Co. Kg Formulation comprising fenofibric acid, a physiologically acceptable salt or derivative thereof
EP2042165A1 (de) * 2007-09-28 2009-04-01 Swiss Caps Rechte und Lizenzen AG Hot-Melt-Befüllte Weichkapseln
FR2999937B1 (fr) * 2012-12-21 2015-01-09 Sanofi Sa Unite solide a haute teneur en fexofenadine et son procede de preparation
US20170119680A1 (en) 2015-10-30 2017-05-04 R.P. Scherer Technologies, Llc Extended release film-coated capsules

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3139383A (en) * 1961-06-26 1964-06-30 Norton Co Encapsulated time release pellets and method for encapsulating the same
US3878217A (en) * 1972-01-28 1975-04-15 Richardson Merrell Inc Alpha-aryl-4-substituted piperidinoalkanol derivatives
GB2118040A (en) * 1982-02-15 1983-10-26 Hoechst Uk Ltd Oral anti-diabetic preparation
DE3237814A1 (de) * 1982-10-12 1984-04-12 Warner-Lambert Co., 07950 Morris Plains, N.J. Wasserfreie emulsionen und verwendung derselben

Also Published As

Publication number Publication date
ES546545A0 (es) 1986-07-16
PH21083A (en) 1987-07-16
PT81028B (pt) 1987-09-18
ATE68972T1 (de) 1991-11-15
DK384985D0 (da) 1985-08-23
JPS6160613A (ja) 1986-03-28
AU4669285A (en) 1986-03-06
NZ213248A (en) 1988-07-28
IE852134L (en) 1986-02-28
ZA856482B (en) 1986-05-28
FI853275A0 (fi) 1985-08-27
IL76237A0 (en) 1986-01-31
GR852078B (es) 1985-12-30
DK164642C (da) 1992-12-14
HUT38248A (en) 1986-05-28
PT81028A (en) 1985-09-01
HU195421B (en) 1988-05-30
FI87992B (fi) 1992-12-15
AU579177B2 (en) 1988-11-17
DE3584557D1 (de) 1991-12-05
IL76237A (en) 1989-01-31
KR920007832B1 (ko) 1992-09-18
EP0173293A3 (en) 1987-07-01
FI87992C (fi) 1993-03-25
EP0173293A2 (en) 1986-03-05
CA1250526A (en) 1989-02-28
AR242341A1 (es) 1993-03-31
DK164642B (da) 1992-07-27
JPH0621068B2 (ja) 1994-03-23
IE58080B1 (en) 1993-06-30
FI853275L (fi) 1986-03-01
DK384985A (da) 1986-03-01
KR870001830A (ko) 1987-03-28
EP0173293B1 (en) 1991-10-30

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20060503