KR870001830A - 고온 용융성 테르페나딘 조성물의 제조방법 - Google Patents

고온 용융성 테르페나딘 조성물의 제조방법 Download PDF

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Publication number
KR870001830A
KR870001830A KR1019850006317A KR850006317A KR870001830A KR 870001830 A KR870001830 A KR 870001830A KR 1019850006317 A KR1019850006317 A KR 1019850006317A KR 850006317 A KR850006317 A KR 850006317A KR 870001830 A KR870001830 A KR 870001830A
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KR
South Korea
Prior art keywords
terpenadine
weight
pharmaceutically acceptable
acceptable salt
parts
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Application number
KR1019850006317A
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English (en)
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KR920007832B1 (ko
Inventor
위팅턴 로저
Original Assignee
개리 디. 스트리트
메렐 다우 파마슈티칼스 인코포레이티드
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Application filed by 개리 디. 스트리트, 메렐 다우 파마슈티칼스 인코포레이티드 filed Critical 개리 디. 스트리트
Publication of KR870001830A publication Critical patent/KR870001830A/ko
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Publication of KR920007832B1 publication Critical patent/KR920007832B1/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

내용 없음.

Description

고온 용융성 테르페나딘 조성물의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (6)

  1. 8내지 28중량부의 테르페나딘 또는 약제학적으로 허용가능한 그의 염 : 0 내지 5중량부의 파라핀 왁스: 및 68내지 92중량부의 폴리에틸렌글리콜로 구성되는, 캅셀에 충진시키기에 적절한 고온 용융성 약제학적 조성물.
  2. 제1항에 있어서, 폴리에틸렌글리콜의 평균 분자량이 3350인 고온 용융성 조성물.
  3. 제1항에 있어서, 1중량부의 파라핀 왁스: 15내지 20중량부의 테르페나딘 또는 약제학적으로 허용 가능한 그의 염: 및 평균 분자량이 3350인 폴리에틸렌글리콜 75내지 85중량부로 구성되는 고온 용융성 조성물.
  4. 60내지 180mg의 테르페나딘 또는 약제학적으로 허용 가능한 그의 염: 0내지 33mg의 피라핀 왁스: 및 450내지 610mg의 폴리에틸렌글리콜을 함유하는 경질 또는 연질 셀 캅셀로 구성되는 용량단위형태의 테르페나딘 조성물.
  5. 제4항에 있어서, 100내지 140mg의 테르-페나딘 또는 약제학적으로 허용 가능한 그의 염: 5내지 10mg의 파라핀 왁스: 및 평균 분자량이 3350인 폴리-에틸렌글리콜 500내지 580mg을 함유하는 용량단위 형태의 테르페나딘 조성물.
  6. 필수적으로 120mg의 테르페나딘 또는 약제학적으로 허용 가능한 그의 염; 6.7mg의 파라핀 왁스; 및 평균 분자량이 3350인 폴리에틸렌글리콜로 구성되는 경질 셀 테르페나딘 캅셀.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019850006317A 1984-08-30 1985-08-30 고온 용융성 테르페니딘 조성물의 제조방법 KR920007832B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US64617984A 1984-08-30 1984-08-30
US646179 1984-08-30
US646,179 1984-08-30

Publications (2)

Publication Number Publication Date
KR870001830A true KR870001830A (ko) 1987-03-28
KR920007832B1 KR920007832B1 (ko) 1992-09-18

Family

ID=24592083

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019850006317A KR920007832B1 (ko) 1984-08-30 1985-08-30 고온 용융성 테르페니딘 조성물의 제조방법

Country Status (19)

Country Link
EP (1) EP0173293B1 (ko)
JP (1) JPH0621068B2 (ko)
KR (1) KR920007832B1 (ko)
AR (1) AR242341A1 (ko)
AT (1) ATE68972T1 (ko)
AU (1) AU579177B2 (ko)
CA (1) CA1250526A (ko)
DE (1) DE3584557D1 (ko)
DK (1) DK164642C (ko)
ES (1) ES8608866A1 (ko)
FI (1) FI87992C (ko)
GR (1) GR852078B (ko)
HU (1) HU195421B (ko)
IE (1) IE58080B1 (ko)
IL (1) IL76237A (ko)
NZ (1) NZ213248A (ko)
PH (1) PH21083A (ko)
PT (1) PT81028B (ko)
ZA (1) ZA856482B (ko)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8507779D0 (en) * 1985-03-26 1985-05-01 Fujisawa Pharmaceutical Co Drug carrier
AR240018A1 (es) * 1987-10-07 1990-01-31 Merrell Pharma Inc Procedimiento para preparar una composicion que comprende derivados de piperidinoalcanol.
AR245888A1 (es) * 1989-01-23 1994-03-30 Merrell Pharma Inc Procedimiento para la preparacion de una composicion farmaceutica liquida de derivados de piperidinoalcanol.
DE69027267T2 (de) * 1989-09-07 1996-10-17 Fuji Photo Film Co Ltd Verfahren zur Verarbeitung eines farbfotografischen Silberhalogenidmaterials
US5270064A (en) * 1991-04-12 1993-12-14 Avian Allure Encapsulated food product with readily removable capsule
US5455045A (en) * 1993-05-13 1995-10-03 Syntex (U.S.A.) Inc. High dose formulations
GB2281697A (en) * 1993-09-14 1995-03-15 Euro Celtique Sa Laxative compositions in capsules
DK0812195T3 (da) 1995-02-28 2003-03-03 Aventis Pharma Inc Farmaceutisk sammensætning til piperidinoalkanolforbindelser
US5574045A (en) * 1995-06-06 1996-11-12 Hoechst Marion Roussel, Inc. Oral pharmaceutical composition of piperidinoalkanol compounds in solution form
NZ501248A (en) * 1997-08-26 2001-06-29 Aventis Pharma Inc Pharmaceutical composition for combination of piperidinoalkanol-decongestant
AUPP279698A0 (en) * 1998-04-03 1998-04-30 Sunscape Developments Limited Sustained release formulation
FR2838349B1 (fr) 2002-04-15 2004-06-25 Laurence Paris Compositions liquides pour capsules molle a liberation prolongee et leur procede de fabrication
EP1829541A1 (en) * 2002-12-17 2007-09-05 Abbott GmbH & Co. KG Formulation comprising fenofibric acid or a physiologically acceptable salt thereof
MXPA05005736A (es) * 2002-12-17 2005-08-16 Abbott Gmbh & Co Kg Formulacion que comprende acido fenofibrico, una sal fisiologicamente aceptable o derivado del mismo.
EP2042165A1 (de) * 2007-09-28 2009-04-01 Swiss Caps Rechte und Lizenzen AG Hot-Melt-Befüllte Weichkapseln
FR2999937B1 (fr) * 2012-12-21 2015-01-09 Sanofi Sa Unite solide a haute teneur en fexofenadine et son procede de preparation
US20170119680A1 (en) 2015-10-30 2017-05-04 R.P. Scherer Technologies, Llc Extended release film-coated capsules

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3139383A (en) * 1961-06-26 1964-06-30 Norton Co Encapsulated time release pellets and method for encapsulating the same
US3878217A (en) * 1972-01-28 1975-04-15 Richardson Merrell Inc Alpha-aryl-4-substituted piperidinoalkanol derivatives
GB2118040A (en) * 1982-02-15 1983-10-26 Hoechst Uk Ltd Oral anti-diabetic preparation
DE3237814A1 (de) * 1982-10-12 1984-04-12 Warner-Lambert Co., 07950 Morris Plains, N.J. Wasserfreie emulsionen und verwendung derselben

Also Published As

Publication number Publication date
DK384985A (da) 1986-03-01
GR852078B (ko) 1985-12-30
JPS6160613A (ja) 1986-03-28
FI87992C (fi) 1993-03-25
PH21083A (en) 1987-07-16
DK384985D0 (da) 1985-08-23
IL76237A (en) 1989-01-31
CA1250526A (en) 1989-02-28
DK164642B (da) 1992-07-27
DK164642C (da) 1992-12-14
ES546545A0 (es) 1986-07-16
JPH0621068B2 (ja) 1994-03-23
FI87992B (fi) 1992-12-15
KR920007832B1 (ko) 1992-09-18
ZA856482B (en) 1986-05-28
AU579177B2 (en) 1988-11-17
AR242341A1 (es) 1993-03-31
EP0173293B1 (en) 1991-10-30
ES8608866A1 (es) 1986-07-16
IL76237A0 (en) 1986-01-31
EP0173293A3 (en) 1987-07-01
HUT38248A (en) 1986-05-28
IE58080B1 (en) 1993-06-30
PT81028B (pt) 1987-09-18
HU195421B (en) 1988-05-30
IE852134L (en) 1986-02-28
FI853275L (fi) 1986-03-01
PT81028A (en) 1985-09-01
ATE68972T1 (de) 1991-11-15
EP0173293A2 (en) 1986-03-05
FI853275A0 (fi) 1985-08-27
AU4669285A (en) 1986-03-06
DE3584557D1 (de) 1991-12-05
NZ213248A (en) 1988-07-28

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