ES8606887A1 - Un metodo para la produccion microbica de interferon. - Google Patents
Un metodo para la produccion microbica de interferon.Info
- Publication number
- ES8606887A1 ES8606887A1 ES540038A ES540038A ES8606887A1 ES 8606887 A1 ES8606887 A1 ES 8606887A1 ES 540038 A ES540038 A ES 540038A ES 540038 A ES540038 A ES 540038A ES 8606887 A1 ES8606887 A1 ES 8606887A1
- Authority
- ES
- Spain
- Prior art keywords
- novel vectors
- interferon expression
- interferon
- expression
- vectors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION MICROBICA DE INTERFERON, QUE TIENE APLICACION PARA LA PRODUCCION DE INTERFERON LEUCOCITARIO HUMANO. COMPRENDE LA TRANSFORMACION DE UN ORGANISMO DE LEVADURA SENSIBLE A LA TEMPERATURA CON UN VECTOR DE EXPRESION QUE CONTIENE EL GEL ESTRUCTURAL PARA UN INTERFERON HUMANO, ENLAZADO DE MODO OPERATIVO A UN PROMOTOR/OPERADOR PHO5; DESARROLLO DEL ORGANISMO TRANSFORMADO EN UN MEDIO DE CULTIVO ADECUADO, A UNA TEMPERATURA COMPRENDIDA ENTRE 30JC Y 35JC; DISMINUCION DE LA TEMPERATURA DEL ORGANISMO HASTA UN VALOR COMPRENDIDO ENTRE 20JC Y 30JC, PARA INDUCIR LA TEMPERATURA DE INTERFERON; LISADO DEL ORGANISMO HUESPED; Y RECUPERACION DEL INTERFERON DEL LISADO RESULTANTE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49167283A | 1983-05-05 | 1983-05-05 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8606887A1 true ES8606887A1 (es) | 1986-05-16 |
ES540038A0 ES540038A0 (es) | 1986-05-16 |
Family
ID=23953166
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES532173A Expired ES8505411A1 (es) | 1983-05-05 | 1984-05-04 | Un metodo para producir interferon |
ES540038A Expired ES8606887A1 (es) | 1983-05-05 | 1985-02-01 | Un metodo para la produccion microbica de interferon. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES532173A Expired ES8505411A1 (es) | 1983-05-05 | 1984-05-04 | Un metodo para producir interferon |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0124874A3 (es) |
JP (1) | JPS60186288A (es) |
AU (1) | AU2767684A (es) |
DK (1) | DK224684A (es) |
ES (2) | ES8505411A1 (es) |
FI (1) | FI841787A (es) |
GR (1) | GR79963B (es) |
HU (1) | HUT34239A (es) |
IL (1) | IL71745A0 (es) |
MC (1) | MC1598A1 (es) |
NO (1) | NO841811L (es) |
NZ (1) | NZ208046A (es) |
PT (1) | PT78552B (es) |
ZA (1) | ZA843275B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0214638A3 (en) * | 1985-09-09 | 1988-08-31 | G.D. Searle & Co. | Yeast promoters |
JPH0655146B2 (ja) * | 1985-12-27 | 1994-07-27 | 財団法人化学及血清療法研究所 | シヤトルベクタ− |
US5013652A (en) * | 1986-10-14 | 1991-05-07 | Genex Corporation | Composite yeast vectors |
DE3635867A1 (de) * | 1986-10-22 | 1988-05-11 | Boehringer Ingelheim Int | Neue hefeexpressionsvektoren fuer ifn-omega, verfahren zu ihrer herstellung und deren verwendung |
KR100374307B1 (ko) * | 1995-07-21 | 2003-07-07 | 주식회사 엘지생명과학 | 재조합효모로부터발현된감마인터페론의정제방법 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ199722A (en) * | 1981-02-25 | 1985-12-13 | Genentech Inc | Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain |
AU561343B2 (en) * | 1981-10-19 | 1987-05-07 | Genentech Inc. | Human immune interferon by recombinant dna |
IE54592B1 (en) * | 1982-03-08 | 1989-12-06 | Genentech Inc | Anumal interferons, processes involved in their production, compositions containing them, dna sequences coding therefor and espression vehicles containing such sequences and cells transformed thereby |
GB2125047B (en) * | 1982-08-09 | 1986-02-19 | Ciba Geigy Ag | Yeast hybrid vectors and their use for the production of polypeptides |
IL72773A0 (en) * | 1983-08-29 | 1984-11-30 | Meloy Lab | Production of immune interferon and its mrna |
-
1984
- 1984-05-02 ZA ZA843275A patent/ZA843275B/xx unknown
- 1984-05-03 EP EP84104967A patent/EP0124874A3/en not_active Withdrawn
- 1984-05-03 IL IL71745A patent/IL71745A0/xx unknown
- 1984-05-03 NZ NZ208046A patent/NZ208046A/en unknown
- 1984-05-04 HU HU841734A patent/HUT34239A/hu unknown
- 1984-05-04 FI FI841787A patent/FI841787A/fi not_active Application Discontinuation
- 1984-05-04 NO NO841811A patent/NO841811L/no unknown
- 1984-05-04 DK DK224684A patent/DK224684A/da not_active Application Discontinuation
- 1984-05-04 ES ES532173A patent/ES8505411A1/es not_active Expired
- 1984-05-04 PT PT78552A patent/PT78552B/pt unknown
- 1984-05-04 GR GR74605A patent/GR79963B/el unknown
- 1984-05-04 MC MC841704A patent/MC1598A1/xx unknown
- 1984-05-04 AU AU27676/84A patent/AU2767684A/en not_active Abandoned
- 1984-05-07 JP JP59090862A patent/JPS60186288A/ja active Pending
-
1985
- 1985-02-01 ES ES540038A patent/ES8606887A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
GR79963B (es) | 1984-10-31 |
NZ208046A (en) | 1988-04-29 |
FI841787A (fi) | 1984-11-06 |
DK224684D0 (da) | 1984-05-04 |
ZA843275B (en) | 1984-12-24 |
EP0124874A2 (en) | 1984-11-14 |
MC1598A1 (fr) | 1985-05-09 |
AU2767684A (en) | 1984-11-08 |
JPS60186288A (ja) | 1985-09-21 |
EP0124874A3 (en) | 1987-03-25 |
ES532173A0 (es) | 1985-06-01 |
PT78552A (en) | 1984-06-01 |
NO841811L (no) | 1984-11-06 |
ES8505411A1 (es) | 1985-06-01 |
IL71745A0 (en) | 1984-09-30 |
ES540038A0 (es) | 1986-05-16 |
FI841787A0 (fi) | 1984-05-04 |
HUT34239A (en) | 1985-02-28 |
DK224684A (da) | 1984-11-06 |
PT78552B (en) | 1986-09-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20001009 |