ES8606404A1 - Amidas dipeptidas analgesicas o antihipertensivas - Google Patents

Amidas dipeptidas analgesicas o antihipertensivas

Info

Publication number
ES8606404A1
ES8606404A1 ES540463A ES540463A ES8606404A1 ES 8606404 A1 ES8606404 A1 ES 8606404A1 ES 540463 A ES540463 A ES 540463A ES 540463 A ES540463 A ES 540463A ES 8606404 A1 ES8606404 A1 ES 8606404A1
Authority
ES
Spain
Prior art keywords
alkyl
amide compound
novel peptide
peptide amide
oco2r1
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES540463A
Other languages
English (en)
Other versions
ES540463A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GD Searle LLC filed Critical GD Searle LLC
Publication of ES540463A0 publication Critical patent/ES540463A0/es
Publication of ES8606404A1 publication Critical patent/ES8606404A1/es
Expired legal-status Critical Current

Links

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  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE AMIDAS DIPEPTIDAS Y DE SUS SALES DE ADICION DE ACIDO FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R1 REPRESENTA ALQUILO C1-4; R3, R4 Y R5 SON HIDROGENO O ALQUILO C1-6; R2 Y A PUEDEN SER VARIOS TIPOS DE RADICALES; Y N VALE 1-6; COMPUESTOS QUE TIENEN APLICACIONES FARMACOLOGICAS COMO AGENTES ANALGESICOS Y ANTIHIPERTENSIVOS. COMPRENDE EL ACOPLAMIENTO DEL COMPUESTO (D)ALA BLOQUEADO DE FORMULA Z-(D)ALAOH CON UN COMPUESTO A AMINOALQUIL-A DE FORMULA NH2(CH2)N-A, EN LAS QUE Z ES UN GRUPO BLOQUEANTE Y N Y A TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), MEDIANTE REACCION CON UN ANHIDRIDO MIXTO; DESBLOQUEO DEL COMPUESTO RESULTANTE; ACOPLAMIENTO DEL COMPUESTO DESBLOQUEADO CON UNA TIROSINA BLOQUEADA, DE FORMULA (II), EN LA QUE TODOS LOS SIMBOLOS SON LOS MISMOS QUE EN LA FORMULA (I), POR REACCION CON UN ANHIDRIDO MIXTO; SEPARACION DE LA MEZCLA DE DIASTEREOISOMEROS FORMADA Y DESBLOQUEO DE CADA UNO DE ELLOS.
ES540463A 1984-02-16 1985-02-15 Amidas dipeptidas analgesicas o antihipertensivas Expired ES8606404A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58097784A 1984-02-16 1984-02-16

Publications (2)

Publication Number Publication Date
ES540463A0 ES540463A0 (es) 1986-04-16
ES8606404A1 true ES8606404A1 (es) 1986-04-16

Family

ID=24323388

Family Applications (1)

Application Number Title Priority Date Filing Date
ES540463A Expired ES8606404A1 (es) 1984-02-16 1985-02-15 Amidas dipeptidas analgesicas o antihipertensivas

Country Status (3)

Country Link
JP (1) JPS60193999A (es)
ES (1) ES8606404A1 (es)
ZA (1) ZA851181B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013520489A (ja) * 2010-02-25 2013-06-06 ファイザー・リミテッド ペプチド類似体
WO2013008123A1 (en) * 2011-07-13 2013-01-17 Pfizer Limited Enkephalin analogues

Also Published As

Publication number Publication date
ES540463A0 (es) 1986-04-16
ZA851181B (en) 1986-04-30
JPS60193999A (ja) 1985-10-02

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970203