ES8605817A1 - Procedimiento para preparar un compuesto seleccionado del grupo constituido de 7-halo-7-desoxilincomicina y analogos de la misma - Google Patents

Procedimiento para preparar un compuesto seleccionado del grupo constituido de 7-halo-7-desoxilincomicina y analogos de la misma

Info

Publication number
ES8605817A1
ES8605817A1 ES548152A ES548152A ES8605817A1 ES 8605817 A1 ES8605817 A1 ES 8605817A1 ES 548152 A ES548152 A ES 548152A ES 548152 A ES548152 A ES 548152A ES 8605817 A1 ES8605817 A1 ES 8605817A1
Authority
ES
Spain
Prior art keywords
preparing
deoxylincomycins
halo
analogue
halodeoxylincomycin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES548152A
Other languages
English (en)
Other versions
ES548152A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of ES8605817A1 publication Critical patent/ES8605817A1/es
Publication of ES548152A0 publication Critical patent/ES548152A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • C07H15/16—Lincomycin; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)

Abstract

PROCEDIMIENTO MEJORADO PARA PREPARAR UN COMPUESTO SELECCIONADO DEL GRUPO CONSTITUIDO DE 7-HALO-7-DESOXILINCOMICINA Y ANALOGOS. CONSISTENTE EN HACER REACCIONAR A LA LINCOMICINA O SUS ANALOGOS CON HALURO DE TIONILO, EN DIMETILFORMAMIDA, A UNA TEMPERATURA ENTRE 0 Y 50JC, DURANTE 10 A 48 HORAS Y EN UNA RELACION EQUIVALENTE DE LINCOMICINA ENTRE 4:1 Y 13:1, PARA OBTENER LA 7-HALO-7-DESOXILINCOMICINA Y ANALOGOS EN FORMA DE BASES LIBRES O SALES HIDRATADAS O ANHIDRAS QUE SON FARMACEUTICAMENTE ACEPTABLES. LOS ANALOGOS DE LICOMICINA SON METILTIOLINCOSAMINIDA, 3,4-CUMILIDEN-LINCOMICINA Y 3,4-BENZILIDEN-LINCOMICINA. EL HALURO DE TIONILO ES CLORURO DE TIONILO Y UN ANALOGO EN FORMA DE SALES O BASES LIBRES DE LA 7-HALO-7-DESOXILINCOMICINA QUE ES LA CLINDAMICINA. SE UTILIZA COMO ANTIBIOTICOS.
ES548152A 1984-11-29 1985-10-23 Procedimiento para preparar un compuesto seleccionado del grupo constituido de 7-halo-7-desoxilincomicina y analogos de la misma Expired ES8605817A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US67615784A 1984-11-29 1984-11-29

Publications (2)

Publication Number Publication Date
ES8605817A1 true ES8605817A1 (es) 1986-04-01
ES548152A0 ES548152A0 (es) 1986-04-01

Family

ID=24713464

Family Applications (1)

Application Number Title Priority Date Filing Date
ES548152A Expired ES8605817A1 (es) 1984-11-29 1985-10-23 Procedimiento para preparar un compuesto seleccionado del grupo constituido de 7-halo-7-desoxilincomicina y analogos de la misma

Country Status (19)

Country Link
US (1) US4710565A (es)
EP (1) EP0183505B1 (es)
JP (1) JPH0649714B2 (es)
KR (1) KR930003492B1 (es)
CN (2) CN1004002B (es)
AT (1) ATE50265T1 (es)
AU (1) AU574232B2 (es)
CA (1) CA1238319A (es)
DE (1) DE3575930D1 (es)
DK (1) DK165010C (es)
ES (1) ES8605817A1 (es)
FI (1) FI78708C (es)
GR (1) GR852861B (es)
HU (1) HU199497B (es)
IL (1) IL76778A (es)
MX (1) MX162251A (es)
PT (1) PT81496B (es)
SU (1) SU1405705A3 (es)
ZA (1) ZA858117B (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4568741A (en) * 1984-05-15 1986-02-04 The Upjohn Company Synthesis of 7-halo-7-deoxylincomycins
JP2531877Y2 (ja) * 1988-12-15 1997-04-09 日東工器株式会社 電磁式ダイアフラムポンプ
JP2531876Y2 (ja) * 1988-12-15 1997-04-09 日東工器株式会社 電磁式ダイアフラムポンプ用マグネットホルダ
JP2544782Y2 (ja) * 1988-12-27 1997-08-20 日東工器株式会社 電磁式ダイアフラムポンプ用マグネットホルダ
US6565882B2 (en) 2000-02-24 2003-05-20 Advancis Pharmaceutical Corp Antibiotic composition with inhibitor
US6544555B2 (en) 2000-02-24 2003-04-08 Advancis Pharmaceutical Corp. Antibiotic product, use and formulation thereof
US20020068078A1 (en) 2000-10-13 2002-06-06 Rudnic Edward M. Antifungal product, use and formulation thereof
US6541014B2 (en) 2000-10-13 2003-04-01 Advancis Pharmaceutical Corp. Antiviral product, use and formulation thereof
BR0212214A (pt) * 2001-08-28 2004-10-19 Pharmacia Corp Base livre de clindamicina cristalina
US7199105B2 (en) * 2002-08-15 2007-04-03 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antibacterial activity
CA2493799A1 (en) * 2002-08-15 2004-02-26 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antibacterial activity
NZ541526A (en) 2003-01-24 2008-03-28 Stiefel Res Australia Pty Ltd Clindamycin phosphate foam
US7256177B2 (en) 2003-06-17 2007-08-14 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antibacterial activity
US7199106B2 (en) 2003-06-17 2007-04-03 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antimicrobial activity
WO2005009365A2 (en) 2003-07-21 2005-02-03 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
WO2005009368A2 (en) 2003-07-21 2005-02-03 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
JP2006528185A (ja) 2003-07-21 2006-12-14 アドバンシス ファーマスーティカル コーポレイション 抗生物質製剤、その使用法及び作成方法
US8758820B2 (en) 2003-08-11 2014-06-24 Shionogi Inc. Robust pellet
CA2535398C (en) 2003-08-12 2013-11-12 Advancis Pharmaceuticals Corporation Antibiotic product, use and formulation thereof
AU2004270170B2 (en) 2003-08-29 2011-01-27 Shionogi, Inc. Antibiotic product, use and formulation thereof
CA2538064C (en) 2003-09-15 2013-12-17 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
US7361743B2 (en) * 2004-02-11 2008-04-22 Pfizer Inc Lincomycin derivatives possessing antibacterial activity
AU2005269981A1 (en) 2004-07-02 2006-02-09 Bonck, John A Tablet for pulsed delivery
US8778924B2 (en) 2006-12-04 2014-07-15 Shionogi Inc. Modified release amoxicillin products
US8357394B2 (en) 2005-12-08 2013-01-22 Shionogi Inc. Compositions and methods for improved efficacy of penicillin-type antibiotics
JP2009528342A (ja) * 2006-02-28 2009-08-06 ヴイ ビー メディケア プライヴェート リミテッド 塩化チオニルを使用する糖類を塩素化するための新規塩素化試薬及び新規方法
KR101368107B1 (ko) 2006-03-31 2014-03-14 스티펠 리서치 오스트레일리아 피티와이 리미티드 발포성 현탁겔
US8299052B2 (en) 2006-05-05 2012-10-30 Shionogi Inc. Pharmaceutical compositions and methods for improved bacterial eradication
CN101205245B (zh) * 2007-12-06 2011-04-06 河南天方药业股份有限公司 盐酸克林霉素的制备方法
CN102675146A (zh) * 2012-05-22 2012-09-19 山东凯盛新材料股份有限公司 新型固体氯化剂（氯亚甲基）二甲基氯化铵的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3496163A (en) * 1965-02-08 1970-02-17 Upjohn Co 7-halo-7-deoxylincomycins and process for preparing the same
US3435025A (en) * 1966-03-18 1969-03-25 Upjohn Co 7-deoxylincomycin and analogs and isomers thereof and process for making the same
US3580904A (en) * 1969-04-03 1971-05-25 Upjohn Co 7-halo-7-deoxy-lincomycin derivatives
US3574186A (en) * 1969-10-08 1971-04-06 Upjohn Co Process for making 7-chloro-7-deoxylincomycin and related compounds and novel intermediates produced therein
US4568741A (en) * 1984-05-15 1986-02-04 The Upjohn Company Synthesis of 7-halo-7-deoxylincomycins

Also Published As

Publication number Publication date
KR930003492B1 (ko) 1993-05-01
AU4883785A (en) 1986-06-05
FI854711A (fi) 1986-05-30
IL76778A (en) 1991-09-16
AU574232B2 (en) 1988-06-30
FI854711A0 (fi) 1985-11-28
CA1238319A (en) 1988-06-21
EP0183505A3 (en) 1987-06-24
IL76778A0 (en) 1986-02-28
HU199497B (en) 1990-02-28
EP0183505B1 (en) 1990-02-07
ZA858117B (en) 1986-06-25
GR852861B (es) 1986-03-28
JPS61137892A (ja) 1986-06-25
MX162251A (es) 1991-04-17
DK165010C (da) 1993-02-22
PT81496A (en) 1985-12-01
CN85101921A (zh) 1987-01-10
HUT40806A (en) 1987-02-27
FI78708B (fi) 1989-05-31
DK542785A (da) 1986-05-30
CN1016694B (zh) 1992-05-20
ES548152A0 (es) 1986-04-01
US4710565A (en) 1987-12-01
DK542785D0 (da) 1985-11-22
SU1405705A3 (ru) 1988-06-23
PT81496B (pt) 1987-11-11
DE3575930D1 (de) 1990-03-15
KR860004077A (ko) 1986-06-16
FI78708C (fi) 1989-09-11
CN1004002B (zh) 1989-04-26
ATE50265T1 (de) 1990-02-15
CN85108244A (zh) 1986-08-20
EP0183505A2 (en) 1986-06-04
JPH0649714B2 (ja) 1994-06-29
DK165010B (da) 1992-09-28

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Legal Events

Date Code Title Description
PC1A Transfer granted
FD1A Patent lapsed

Effective date: 20051219