ES8603836A1 - Procedimiento para preparar nuevos derivados de quinoleina - Google Patents

Procedimiento para preparar nuevos derivados de quinoleina

Info

Publication number
ES8603836A1
ES8603836A1 ES543014A ES543014A ES8603836A1 ES 8603836 A1 ES8603836 A1 ES 8603836A1 ES 543014 A ES543014 A ES 543014A ES 543014 A ES543014 A ES 543014A ES 8603836 A1 ES8603836 A1 ES 8603836A1
Authority
ES
Spain
Prior art keywords
preparation
same
compositions containing
therapeutic compositions
quinoline derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES543014A
Other languages
English (en)
Other versions
ES543014A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Publication of ES543014A0 publication Critical patent/ES543014A0/es
Publication of ES8603836A1 publication Critical patent/ES8603836A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)

Abstract

UN PROCEDIMIENTO DE PREPARACION DE NUEVOS DERIVADOS DE QUINOLEINA DE FORMULA (I). COMPRENDE HACER REACCIONAR, DURANTE 12-24 HORAS, A 70-95JC, EN DIMETILFORMAMIDA, LA 1,4-DIHIDRO-3-ETOXICARBONIL-6,8-DIFLUORO-4-OXO-QUINOLEINA CON UN EXCESO DE RX (2-5 MOLES DE RX POR MOL DE QUINOLEINA), EN PRESENCIA DE K2CO3, Y POSTERIORMENTE HIDROLIZAR EL 3-ESTER OBTENIDO CON HCL BAJO CONDICIONES DE REFLUJO.
ES543014A 1984-05-11 1985-05-10 Procedimiento para preparar nuevos derivados de quinoleina Expired ES8603836A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848412094A GB8412094D0 (en) 1984-05-11 1984-05-11 Quinoline derivatives

Publications (2)

Publication Number Publication Date
ES543014A0 ES543014A0 (es) 1986-01-01
ES8603836A1 true ES8603836A1 (es) 1986-01-01

Family

ID=10560821

Family Applications (1)

Application Number Title Priority Date Filing Date
ES543014A Expired ES8603836A1 (es) 1984-05-11 1985-05-10 Procedimiento para preparar nuevos derivados de quinoleina

Country Status (26)

Country Link
US (1) US4782068A (es)
JP (1) JPS60246370A (es)
AR (1) AR240920A1 (es)
AT (1) AT391314B (es)
BE (1) BE902337A (es)
CA (1) CA1291136C (es)
CH (1) CH664363A5 (es)
DE (1) DE3516938A1 (es)
DK (1) DK163826C (es)
DZ (1) DZ779A1 (es)
ES (1) ES8603836A1 (es)
FI (1) FI82688C (es)
FR (2) FR2563995B1 (es)
GB (2) GB8412094D0 (es)
HK (1) HK57288A (es)
IE (1) IE58304B1 (es)
IT (1) IT1200472B (es)
LU (1) LU85876A1 (es)
MA (1) MA20427A1 (es)
NL (1) NL8501309A (es)
NO (1) NO167025C (es)
OA (1) OA08030A (es)
PT (1) PT80433B (es)
SE (1) SE463152B (es)
SG (1) SG23388G (es)
ZA (1) ZA853268B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2049652A1 (es) * 1992-09-16 1994-04-16 Genesis Para La Investigacion Procedimiento para la preparacion de un acido quinolin carboxilico.

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2206564C1 (ru) * 2002-03-07 2003-06-20 Общество с ограниченной ответственностью "Поливит" Способ получения этилового эфира 6-фтор-7-хлор-1,4-дигидро-4-оксо-3-хинолинкарбоновой кислоты

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146625A (en) * 1976-07-16 1979-03-27 E. I. Du Pont De Nemours And Company Quinolonecarboxylic acids for control of bacterial diseases in plants
US4264604A (en) * 1977-07-01 1981-04-28 Ciba-Geigy Corporation Quinolonecarboxylic acid derivatives as bactericides
JPS5630964A (en) * 1979-08-22 1981-03-28 Kyorin Pharmaceut Co Ltd Novel substituted quinolinecarboxylic acid and its preparation
JPS5653656A (en) * 1979-10-05 1981-05-13 Tanabe Seiyaku Co Ltd Quinoline derivative and its preparation
DE3142854A1 (de) * 1981-10-29 1983-05-11 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-piperazino-chinolin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2049652A1 (es) * 1992-09-16 1994-04-16 Genesis Para La Investigacion Procedimiento para la preparacion de un acido quinolin carboxilico.

Also Published As

Publication number Publication date
DE3516938C2 (es) 1989-10-26
GB2163742A (en) 1986-03-05
CH664363A5 (fr) 1988-02-29
JPH0354936B2 (es) 1991-08-21
DK207985D0 (da) 1985-05-10
ES543014A0 (es) 1986-01-01
MA20427A1 (fr) 1985-12-31
DK207985A (da) 1985-11-12
IT1200472B (it) 1989-01-18
ATA143885A (de) 1990-03-15
ZA853268B (en) 1985-12-24
PT80433B (pt) 1987-08-19
OA08030A (fr) 1987-01-31
IE58304B1 (en) 1993-09-08
SE8502310D0 (sv) 1985-05-09
FI82688B (fi) 1990-12-31
BE902337A (fr) 1985-09-02
JPS60246370A (ja) 1985-12-06
DK163826C (da) 1992-09-14
US4782068A (en) 1988-11-01
GB8510975D0 (en) 1985-06-05
HK57288A (en) 1988-08-05
SE463152B (sv) 1990-10-15
DK163826B (da) 1992-04-06
GB2163742B (en) 1987-09-23
DZ779A1 (fr) 2004-09-13
FR2564094A1 (fr) 1985-11-15
LU85876A1 (fr) 1986-01-14
NO167025C (no) 1991-09-25
FR2563995B1 (fr) 1987-07-31
FI851774A0 (fi) 1985-05-06
IE851161L (en) 1985-11-11
SG23388G (en) 1988-07-15
IT8520655A0 (it) 1985-05-10
FI82688C (fi) 1991-04-10
NO851868L (no) 1985-11-12
FR2564094B1 (fr) 1986-12-19
GB8412094D0 (en) 1984-06-20
FI851774L (fi) 1985-11-12
SE8502310L (sv) 1985-11-12
FR2563995A1 (fr) 1985-11-15
CA1291136C (en) 1991-10-22
AR240920A2 (es) 1991-03-27
NL8501309A (nl) 1985-12-02
NO167025B (no) 1991-06-17
PT80433A (en) 1985-06-01
DE3516938A1 (de) 1985-11-14
AT391314B (de) 1990-09-25
AR240920A1 (es) 1991-03-27

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000601