ES8601907A1 - Procedimiento para preparar imidazolinas. - Google Patents
Procedimiento para preparar imidazolinas.Info
- Publication number
- ES8601907A1 ES8601907A1 ES530345A ES530345A ES8601907A1 ES 8601907 A1 ES8601907 A1 ES 8601907A1 ES 530345 A ES530345 A ES 530345A ES 530345 A ES530345 A ES 530345A ES 8601907 A1 ES8601907 A1 ES 8601907A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- imidazolines
- bridge
- compound
- rent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/18—Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/34—Monohydroxylic alcohols containing six-membered aromatic rings and other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/06—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D233/22—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/475,193 US4540705A (en) | 1983-03-14 | 1983-03-14 | Antidepressant imidazolines and related compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8601907A1 true ES8601907A1 (es) | 1985-11-16 |
| ES530345A0 ES530345A0 (es) | 1985-11-16 |
Family
ID=23886585
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES530345A Granted ES530345A0 (es) | 1983-03-14 | 1984-03-07 | Procedimiento para preparar imidazolinas. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4540705A (h) |
| EP (1) | EP0125410A3 (h) |
| JP (1) | JPS59193875A (h) |
| KR (1) | KR900001216B1 (h) |
| AU (1) | AU568839B2 (h) |
| CA (1) | CA1215369A (h) |
| DK (1) | DK112984A (h) |
| ES (1) | ES530345A0 (h) |
| FI (1) | FI840839A7 (h) |
| GR (1) | GR81813B (h) |
| IL (1) | IL70966A (h) |
| NO (1) | NO840893L (h) |
| NZ (1) | NZ207184A (h) |
| PH (1) | PH19715A (h) |
| PT (1) | PT78195B (h) |
| ZA (1) | ZA841323B (h) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9016800D0 (en) * | 1990-07-31 | 1990-09-12 | Shell Int Research | Tetrahydropyrimidine derivatives |
| US6559157B2 (en) | 1997-10-02 | 2003-05-06 | Daiichi Pharmaceutical Co., Ltd. | Dihydronaphthalene compounds |
| KR20000069426A (ko) * | 1997-10-02 | 2000-11-25 | 이시가와 데쯔로 | 신규의 디히드로나프탈렌 화합물 및 그 제조방법 |
| US6841684B2 (en) | 1997-12-04 | 2005-01-11 | Allergan, Inc. | Imidiazoles having reduced side effects |
| US6329369B1 (en) | 1997-12-04 | 2001-12-11 | Allergan Sales, Inc. | Methods of treating pain and other conditions |
| AU2003099A (en) * | 1997-12-19 | 1999-07-12 | Eli Lilly And Company | Method for treating diabetes |
| EP1266897A3 (en) * | 1997-12-19 | 2003-12-03 | Eli Lilly And Company | Hypoglycemic imidazoline compounds |
| US6410562B1 (en) | 1998-12-18 | 2002-06-25 | Eli Lilly And Company | Hypoglycemic imidazoline compounds |
| FR2787451B1 (fr) * | 1998-12-18 | 2001-01-26 | Adir | Nouveaux composes imidazoliniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| CA2637312A1 (en) * | 2006-01-27 | 2007-08-02 | F. Hoffmann-La Roche Ag | Use of substituted 2-imidazole of imidazoline derivatives |
| KR101176699B1 (ko) | 2006-10-19 | 2012-08-23 | 에프. 호프만-라 로슈 아게 | 아미노메틸-4-이미다졸 |
| ES2375578T3 (es) | 2006-11-02 | 2012-03-02 | F. Hoffmann-La Roche Ag | 2-imidazoles sustituidos como moduladores de receptores asociados a aminas trazas. |
| EP2084152A2 (en) | 2006-11-16 | 2009-08-05 | F. Hoffmann-Roche AG | Substituted 4-imidazoles |
| ATE509628T1 (de) | 2006-12-13 | 2011-06-15 | Hoffmann La Roche | Neue 2-imidazole als liganden für trace amine associated receptors (taar) |
| US20080146523A1 (en) | 2006-12-18 | 2008-06-19 | Guido Galley | Imidazole derivatives |
| US7582691B2 (en) * | 2007-01-17 | 2009-09-01 | Sabic Innovative Plastics Ip B.V. | Poly(arylene ether) compositions and articles |
| MX2009008255A (es) | 2007-02-02 | 2009-08-12 | Hoffmann La Roche | Nuevas 2-aminooxazolinas como ligandos taar1. |
| JP5130305B2 (ja) | 2007-02-15 | 2013-01-30 | エフ．ホフマン−ラ ロシュ アーゲー | Ｔａａｒ１リガンドとしての２−アミノオキサゾリン |
| KR101150561B1 (ko) | 2007-07-02 | 2012-06-08 | 에프. 호프만-라 로슈 아게 | 미량 아민 결합 수용체(ｔａａｒ)에 대한 양호한 친화도를 갖는 2-이미다졸린 |
| JP2010531836A (ja) | 2007-07-03 | 2010-09-30 | エフ．ホフマン−ラ ロシュ アーゲー | ４−イミダゾリン及びそれらの抗うつ剤としての使用 |
| RU2010104632A (ru) | 2007-07-27 | 2011-09-20 | Ф.Хоффманн-Ля Рош Аг (Ch) | 2-азетидинметанамины и 2-пирролидинметанамины в качестве лигандов taar |
| JP5341084B2 (ja) | 2007-08-03 | 2013-11-13 | エフ．ホフマン−ラ ロシュ アーゲー | Ｔａａｒ１リガンドとしてのピリジンカルボキシアミド及びベンズアミド誘導体 |
| US8242153B2 (en) | 2008-07-24 | 2012-08-14 | Hoffmann-La Roche Inc. | 4,5-dihydro-oxazol-2YL derivatives |
| US8354441B2 (en) | 2009-11-11 | 2013-01-15 | Hoffmann-La Roche Inc. | Oxazoline derivatives |
| US9452980B2 (en) | 2009-12-22 | 2016-09-27 | Hoffmann-La Roche Inc. | Substituted benzamides |
| SI3430010T1 (sl) | 2016-03-17 | 2020-10-30 | F. Hoffmann-La Roche Ag | Derivat 5-etil-4-metil-pirazol-3-karboksamida z aktivnostjo agonista TAAR |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2731471A (en) * | 1956-01-17 | Nxg hi | ||
| US2161938A (en) * | 1934-07-31 | 1939-06-13 | Soc Of Chemical Ind | Imidazolines |
| FR926661A (fr) * | 1941-07-09 | 1947-10-08 | Lovens Kemiske Fabrik V Aug Ko | Méthyle-imidazolines substituées et leur procédé de préparation |
| GB757650A (en) * | 1953-06-15 | 1956-09-19 | Pfizer & Co C | Improvements in or relating to substituted imidazolines and the preparation thereof |
| DE1150180B (de) * | 1962-04-12 | 1963-06-12 | Merck Ag E | Mittel zur Vorbehandlung der Haut fuer die Rasur |
| GB1317514A (en) * | 1970-11-30 | 1973-05-23 | Erba Carlo Spa | Imidazoline derivatives |
| US4085209A (en) * | 1975-02-05 | 1978-04-18 | Rohm And Haas Company | Preparation and safening effect of 1-substituted imidazole metal salt complexes |
-
1983
- 1983-03-14 US US06/475,193 patent/US4540705A/en not_active Expired - Fee Related
-
1984
- 1984-02-15 IL IL70966A patent/IL70966A/xx not_active IP Right Cessation
- 1984-02-16 NZ NZ207184A patent/NZ207184A/en unknown
- 1984-02-23 ZA ZA841323A patent/ZA841323B/xx unknown
- 1984-02-23 PH PH30284A patent/PH19715A/en unknown
- 1984-02-23 AU AU24877/84A patent/AU568839B2/en not_active Ceased
- 1984-02-28 DK DK112984A patent/DK112984A/da not_active Application Discontinuation
- 1984-02-29 GR GR73944A patent/GR81813B/el unknown
- 1984-03-02 PT PT78195A patent/PT78195B/pt unknown
- 1984-03-02 FI FI840839A patent/FI840839A7/fi not_active Application Discontinuation
- 1984-03-05 EP EP84102382A patent/EP0125410A3/en not_active Withdrawn
- 1984-03-07 ES ES530345A patent/ES530345A0/es active Granted
- 1984-03-08 NO NO840893A patent/NO840893L/no unknown
- 1984-03-09 JP JP59045333A patent/JPS59193875A/ja active Pending
- 1984-03-09 KR KR1019840001189A patent/KR900001216B1/ko not_active Expired
- 1984-03-13 CA CA000449452A patent/CA1215369A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS59193875A (ja) | 1984-11-02 |
| KR900001216B1 (ko) | 1990-02-28 |
| US4540705A (en) | 1985-09-10 |
| DK112984D0 (da) | 1984-02-28 |
| PH19715A (en) | 1986-06-17 |
| FI840839A7 (fi) | 1984-09-15 |
| AU2487784A (en) | 1984-09-20 |
| DK112984A (da) | 1984-09-15 |
| NO840893L (no) | 1984-09-17 |
| IL70966A0 (en) | 1984-05-31 |
| PT78195B (en) | 1986-04-24 |
| KR840008327A (ko) | 1984-12-14 |
| AU568839B2 (en) | 1988-01-14 |
| EP0125410A2 (en) | 1984-11-21 |
| ES530345A0 (es) | 1985-11-16 |
| IL70966A (en) | 1987-08-31 |
| NZ207184A (en) | 1986-12-05 |
| FI840839A0 (fi) | 1984-03-02 |
| GR81813B (h) | 1984-12-12 |
| PT78195A (en) | 1984-04-01 |
| ZA841323B (en) | 1984-10-31 |
| EP0125410A3 (en) | 1987-01-14 |
| CA1215369A (en) | 1986-12-16 |
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