ES8601305A1 - Un procedimiento para la preparacion de derivados del acido beta-hidroxibutirico gamma-sustituidos - Google Patents
Un procedimiento para la preparacion de derivados del acido beta-hidroxibutirico gamma-sustituidosInfo
- Publication number
- ES8601305A1 ES8601305A1 ES83527807A ES527807A ES8601305A1 ES 8601305 A1 ES8601305 A1 ES 8601305A1 ES 83527807 A ES83527807 A ES 83527807A ES 527807 A ES527807 A ES 527807A ES 8601305 A1 ES8601305 A1 ES 8601305A1
- Authority
- ES
- Spain
- Prior art keywords
- substitute
- gamma
- general formula
- carnitine
- preparing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
- WHBMMWSBFZVSSR-UHFFFAOYSA-N 3-hydroxybutyric acid Chemical class CC(O)CC(O)=O WHBMMWSBFZVSSR-UHFFFAOYSA-N 0.000 abstract 2
- WDJHALXBUFZDSR-UHFFFAOYSA-N Acetoacetic acid Natural products CC(=O)CC(O)=O WDJHALXBUFZDSR-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 230000036528 appetite Effects 0.000 abstract 1
- 235000019789 appetite Nutrition 0.000 abstract 1
- WOWBFOBYOAGEEA-UHFFFAOYSA-N diafenthiuron Chemical class CC(C)C1=C(NC(=S)NC(C)(C)C)C(C(C)C)=CC(OC=2C=CC=CC=2)=C1 WOWBFOBYOAGEEA-UHFFFAOYSA-N 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
- C12P7/26—Ketones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/447,171 US4642290A (en) | 1982-12-06 | 1982-12-06 | Process for preparing a compound for use in the production of L-carnitine |
| US54495783A | 1983-10-24 | 1983-10-24 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES527807A0 ES527807A0 (es) | 1985-11-01 |
| ES8601305A1 true ES8601305A1 (es) | 1985-11-01 |
Family
ID=27034888
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES83527807A Expired ES8601305A1 (es) | 1982-12-06 | 1983-12-05 | Un procedimiento para la preparacion de derivados del acido beta-hidroxibutirico gamma-sustituidos |
Country Status (23)
| Country | Link |
|---|---|
| JP (1) | JPH0767674A (enExample) |
| KR (1) | KR840008165A (enExample) |
| AT (1) | AT393136B (enExample) |
| AU (1) | AU566906B2 (enExample) |
| CA (1) | CA1225956A (enExample) |
| CH (1) | CH661498A5 (enExample) |
| DE (1) | DE3344085C2 (enExample) |
| DK (1) | DK163917C (enExample) |
| ES (1) | ES8601305A1 (enExample) |
| FI (1) | FI81115C (enExample) |
| FR (1) | FR2537130B1 (enExample) |
| GB (1) | GB2132614B (enExample) |
| GR (1) | GR78767B (enExample) |
| IE (1) | IE56322B1 (enExample) |
| IL (1) | IL70352A (enExample) |
| IT (1) | IT1167289B (enExample) |
| LU (1) | LU85115A1 (enExample) |
| NL (1) | NL8304190A (enExample) |
| NO (1) | NO159291C (enExample) |
| PH (1) | PH20456A (enExample) |
| PT (1) | PT77780B (enExample) |
| SE (1) | SE455501B (enExample) |
| TR (1) | TR23136A (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0144832A3 (de) * | 1983-12-06 | 1987-01-21 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Verfahren zur Herstellung optisch aktiver, alpha-substituierter 3-Hydroxypropionsäurederivate |
| IT1181908B (it) * | 1984-07-12 | 1987-09-30 | Debi Derivati Biologici | Procedimento per la preparazione di l-carnitina |
| IT1181812B (it) * | 1984-07-27 | 1987-09-30 | Sigma Tau Ind Farmaceuti | Procedimento per la preparazione dell'acido gamma-dimetilammino l-beta-idrossibutirrico |
| IT1190358B (it) * | 1985-05-24 | 1988-02-16 | Sclavo Spa | Procedimento per la preparazione di l-carnitina |
| JPS62126997A (ja) * | 1985-11-28 | 1987-06-09 | Nippon Synthetic Chem Ind Co Ltd:The | 光学活性のγ−ハロ−βヒドロキシ酪酸エステルの製造法 |
| IT1189070B (it) * | 1986-03-14 | 1988-01-28 | Donegani Guido Ist | Processo per la preparazione della l(-)-carnitina cloruro a partire da esteri 3,4-epossibutirrici |
| JPH0678277B2 (ja) * | 1988-02-19 | 1994-10-05 | 高砂香料工業株式会社 | 光学活性アルコールおよびその誘導体の製造方法 |
| JP2939646B2 (ja) * | 1990-07-17 | 1999-08-25 | チッソ株式会社 | ４―置換―２―ヒドロキシブタン酸エステルおよび製造法 |
| US5215919A (en) * | 1991-02-25 | 1993-06-01 | Takeda Chemical Industries, Ltd. | Process for producing optically active 2-hydroxycycloalkanecarboxylic acid esters using microbially derived reductase |
| US5324662A (en) | 1992-05-15 | 1994-06-28 | E. R. Squibb & Sons, Inc. | Stereoselective microbial or enzymatic reduction of 3,5-dioxo esters to 3-hydroxy-5-oxo, 3-oxo-5-hydroxy, and 3,5-dihydroxy esters |
| JP3155107B2 (ja) * | 1993-01-12 | 2001-04-09 | ダイセル化学工業株式会社 | 光学活性４−ハロ−３−ヒドロキシ酪酸エステルの製造方法 |
| JP2000189170A (ja) | 1998-05-08 | 2000-07-11 | Daicel Chem Ind Ltd | 光学活性４―ハロ―３―ヒドロキシ酪酸エステルの製造方法 |
| ATE375989T1 (de) | 1998-08-05 | 2007-11-15 | Kaneka Corp | Verfahren zur herstellung von 3,5-dihydroxy substituierten estern als zwischenprodukte zur herstellung optisch aktiver 2-(6-(hydroxymethyl)- 1,3-dioxan-4-yl)-essigsäure-derivate |
| AU2003258187A1 (en) * | 2002-08-09 | 2004-02-25 | Codexis, Inc. | Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives |
| DE10315760A1 (de) * | 2003-04-07 | 2004-10-21 | Basf Ag | L-Carnitin Dehydrogenasen, deren Derivate und ein Verfahren zur Herstellung von substituierten (S)-Alkanolen |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3931410A (en) * | 1974-02-28 | 1976-01-06 | The Upjohn Company | Composition and method of use |
| CH589604A5 (enExample) * | 1974-04-26 | 1977-07-15 | Lonza Ag | |
| JPS5139634A (en) * | 1974-09-27 | 1976-04-02 | Ono Pharmaceutical Co | Ganma amino beeta hidorokishibutansananirido no seizoho |
| JPS6017776B2 (ja) * | 1979-11-07 | 1985-05-07 | 電気化学工業株式会社 | γ−クロロ−β−ヒドロキシ酪酸アルキルエステルの製法 |
| JPS5950661B2 (ja) * | 1980-07-28 | 1984-12-10 | 電気化学工業株式会社 | γ−アミノ−β−ヒドロキシ酪酸の製造法 |
| JPS5950663B2 (ja) * | 1981-04-28 | 1984-12-10 | 電気化学工業株式会社 | γ−アミノ−β−ヒドロキシ酪酸の製造法 |
-
1983
- 1983-11-22 IE IE2732/83A patent/IE56322B1/en not_active IP Right Cessation
- 1983-11-28 AU AU21758/83A patent/AU566906B2/en not_active Ceased
- 1983-11-29 CA CA000442170A patent/CA1225956A/en not_active Expired
- 1983-11-30 IL IL8370352A patent/IL70352A/xx not_active IP Right Cessation
- 1983-12-01 GR GR73128A patent/GR78767B/el unknown
- 1983-12-02 FI FI834419A patent/FI81115C/fi not_active IP Right Cessation
- 1983-12-02 CH CH6448/83A patent/CH661498A5/it not_active IP Right Cessation
- 1983-12-05 DK DK559283A patent/DK163917C/da not_active IP Right Cessation
- 1983-12-05 ES ES83527807A patent/ES8601305A1/es not_active Expired
- 1983-12-05 IT IT8324018A patent/IT1167289B/it active
- 1983-12-05 PH PH29928A patent/PH20456A/en unknown
- 1983-12-05 NO NO834461A patent/NO159291C/no unknown
- 1983-12-05 GB GB08332359A patent/GB2132614B/en not_active Expired
- 1983-12-05 LU LU85115A patent/LU85115A1/fr unknown
- 1983-12-05 AT AT4237/83A patent/AT393136B/de not_active IP Right Cessation
- 1983-12-05 SE SE8306714A patent/SE455501B/sv not_active IP Right Cessation
- 1983-12-06 KR KR1019830005765A patent/KR840008165A/ko not_active Ceased
- 1983-12-06 TR TR10354/83A patent/TR23136A/xx unknown
- 1983-12-06 DE DE3344085A patent/DE3344085C2/de not_active Expired - Fee Related
- 1983-12-06 NL NL8304190A patent/NL8304190A/nl not_active Application Discontinuation
- 1983-12-06 PT PT77780A patent/PT77780B/pt not_active IP Right Cessation
- 1983-12-06 FR FR8319505A patent/FR2537130B1/fr not_active Expired
-
1993
- 1993-09-01 JP JP21771093A patent/JPH0767674A/ja active Pending
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970519 |