IL70352A - L-beta-hydroxy-epsilon-substituted butryic acid derivatives,enzymatic process for preparing them and their use for preparing l-carnitine - Google Patents

L-beta-hydroxy-epsilon-substituted butryic acid derivatives,enzymatic process for preparing them and their use for preparing l-carnitine

Info

Publication number
IL70352A
IL70352A IL8370352A IL7035283A IL70352A IL 70352 A IL70352 A IL 70352A IL 8370352 A IL8370352 A IL 8370352A IL 7035283 A IL7035283 A IL 7035283A IL 70352 A IL70352 A IL 70352A
Authority
IL
Israel
Prior art keywords
preparing
carnitine
epsilon
beta
hydroxy
Prior art date
Application number
IL8370352A
Other versions
IL70352A0 (en
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/447,171 external-priority patent/US4642290A/en
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of IL70352A0 publication Critical patent/IL70352A0/en
Publication of IL70352A publication Critical patent/IL70352A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
IL8370352A 1982-12-06 1983-11-30 L-beta-hydroxy-epsilon-substituted butryic acid derivatives,enzymatic process for preparing them and their use for preparing l-carnitine IL70352A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/447,171 US4642290A (en) 1982-12-06 1982-12-06 Process for preparing a compound for use in the production of L-carnitine
US54495783A 1983-10-24 1983-10-24

Publications (2)

Publication Number Publication Date
IL70352A0 IL70352A0 (en) 1984-02-29
IL70352A true IL70352A (en) 1987-10-20

Family

ID=27034888

Family Applications (1)

Application Number Title Priority Date Filing Date
IL8370352A IL70352A (en) 1982-12-06 1983-11-30 L-beta-hydroxy-epsilon-substituted butryic acid derivatives,enzymatic process for preparing them and their use for preparing l-carnitine

Country Status (23)

Country Link
JP (1) JPH0767674A (en)
KR (1) KR840008165A (en)
AT (1) AT393136B (en)
AU (1) AU566906B2 (en)
CA (1) CA1225956A (en)
CH (1) CH661498A5 (en)
DE (1) DE3344085C2 (en)
DK (1) DK163917C (en)
ES (1) ES527807A0 (en)
FI (1) FI81115C (en)
FR (1) FR2537130B1 (en)
GB (1) GB2132614B (en)
GR (1) GR78767B (en)
IE (1) IE56322B1 (en)
IL (1) IL70352A (en)
IT (1) IT1167289B (en)
LU (1) LU85115A1 (en)
NL (1) NL8304190A (en)
NO (1) NO159291C (en)
PH (1) PH20456A (en)
PT (1) PT77780B (en)
SE (1) SE455501B (en)
TR (1) TR23136A (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0144832A3 (en) * 1983-12-06 1987-01-21 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Process for the preparation of optically active alpha-substituted 3-hydroxypropionic-acid derivatives
IT1181908B (en) * 1984-07-12 1987-09-30 Debi Derivati Biologici PROCEDURE FOR THE PREPARATION OF L-CARNITINA
IT1181812B (en) * 1984-07-27 1987-09-30 Sigma Tau Ind Farmaceuti PROCEDURE FOR THE PREPARATION OF THE GAMMA-DIMETHYLAMINE L-BETA-HYDROXYBUTIRRIC ACID
IT1190358B (en) * 1985-05-24 1988-02-16 Sclavo Spa PROCEDURE FOR THE PREPARATION OF L-CARNITINA
JPS62126997A (en) * 1985-11-28 1987-06-09 Nippon Synthetic Chem Ind Co Ltd:The Production of optically active gamma-halo-beta hydroxybutyric ester
IT1189070B (en) * 1986-03-14 1988-01-28 Donegani Guido Ist PROCESS FOR THE PREPARATION OF THE L (-) - CARNITINE CHLORIDE FROM FOREIGN 3,4-EPOXYBUTYRRICS
JPH0678277B2 (en) * 1988-02-19 1994-10-05 高砂香料工業株式会社 Process for producing optically active alcohol and its derivative
JP2939646B2 (en) * 1990-07-17 1999-08-25 チッソ株式会社 4-Substituted-2-hydroxybutanoic acid esters and production method
US5215919A (en) * 1991-02-25 1993-06-01 Takeda Chemical Industries, Ltd. Process for producing optically active 2-hydroxycycloalkanecarboxylic acid esters using microbially derived reductase
US5324662A (en) 1992-05-15 1994-06-28 E. R. Squibb & Sons, Inc. Stereoselective microbial or enzymatic reduction of 3,5-dioxo esters to 3-hydroxy-5-oxo, 3-oxo-5-hydroxy, and 3,5-dihydroxy esters
JP3155107B2 (en) * 1993-01-12 2001-04-09 ダイセル化学工業株式会社 Method for producing optically active 4-halo-3-hydroxybutyrate
JP2000189170A (en) * 1998-05-08 2000-07-11 Daicel Chem Ind Ltd Production of optically active 4-halo-3-hydroxybutyric acid ester
DE69937374T2 (en) 1998-08-05 2008-07-24 Kaneka Corp. Process for the preparation of 3,5-dihydroxy substituted esters as intermediates for the preparation of optically active 2- (6- (hydroxymethyl) -1,3-dioxan-4-yl) acetic acid derivatives
WO2004015132A2 (en) * 2002-08-09 2004-02-19 Codexis, Inc. Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives
DE10315760A1 (en) * 2003-04-07 2004-10-21 Basf Ag L-carnitine dehydrogenases, their derivatives and a process for the preparation of substituted (S) -alkanols

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3931410A (en) * 1974-02-28 1976-01-06 The Upjohn Company Composition and method of use
CH589604A5 (en) * 1974-04-26 1977-07-15 Lonza Ag
JPS5139634A (en) * 1974-09-27 1976-04-02 Ono Pharmaceutical Co Ganma amino beeta hidorokishibutansananirido no seizoho
JPS6017776B2 (en) * 1979-11-07 1985-05-07 電気化学工業株式会社 Production method of γ-chloro-β-hydroxybutyric acid alkyl ester
JPS5950661B2 (en) * 1980-07-28 1984-12-10 電気化学工業株式会社 Method for producing γ-amino-β-hydroxybutyric acid
JPS5950663B2 (en) * 1981-04-28 1984-12-10 電気化学工業株式会社 Method for producing γ-amino-β-hydroxybutyric acid

Also Published As

Publication number Publication date
IL70352A0 (en) 1984-02-29
ATA423783A (en) 1991-01-15
FI81115C (en) 1990-09-10
FI834419A (en) 1984-06-07
LU85115A1 (en) 1984-04-02
DE3344085C2 (en) 1993-10-14
DK163917C (en) 1992-09-14
IE56322B1 (en) 1991-06-19
FR2537130B1 (en) 1988-10-14
CA1225956A (en) 1987-08-25
DK559283A (en) 1984-06-07
AT393136B (en) 1991-08-26
PH20456A (en) 1987-01-14
IT1167289B (en) 1987-05-13
FI81115B (en) 1990-05-31
SE455501B (en) 1988-07-18
NL8304190A (en) 1984-07-02
PT77780A (en) 1984-01-01
ES8601305A1 (en) 1985-11-01
NO159291B (en) 1988-09-05
SE8306714L (en) 1984-06-07
AU2175883A (en) 1984-06-14
FI834419A0 (en) 1983-12-02
KR840008165A (en) 1984-12-13
IT8324018A0 (en) 1983-12-05
TR23136A (en) 1989-04-11
GB2132614A (en) 1984-07-11
FR2537130A1 (en) 1984-06-08
DK559283D0 (en) 1983-12-05
SE8306714D0 (en) 1983-12-05
GB8332359D0 (en) 1984-01-11
DK163917B (en) 1992-04-21
JPH0767674A (en) 1995-03-14
NO834461L (en) 1984-06-07
NO159291C (en) 1988-12-14
ES527807A0 (en) 1985-11-01
GB2132614B (en) 1986-03-26
DE3344085A1 (en) 1984-06-07
CH661498A5 (en) 1987-07-31
IE832732L (en) 1984-06-06
GR78767B (en) 1984-10-02
PT77780B (en) 1986-04-17
AU566906B2 (en) 1987-11-05

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