ES8505542A1 - Formulacion parenteral de nimodipina, un procedimiento para su preparacion, asi como su empleo en la lucha contra enfermedades - Google Patents

Formulacion parenteral de nimodipina, un procedimiento para su preparacion, asi como su empleo en la lucha contra enfermedades

Info

Publication number
ES8505542A1
ES8505542A1 ES531995A ES531995A ES8505542A1 ES 8505542 A1 ES8505542 A1 ES 8505542A1 ES 531995 A ES531995 A ES 531995A ES 531995 A ES531995 A ES 531995A ES 8505542 A1 ES8505542 A1 ES 8505542A1
Authority
ES
Spain
Prior art keywords
weight
nimodipine
parenteral formulation
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES531995A
Other languages
English (en)
Spanish (es)
Other versions
ES531995A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES531995A0 publication Critical patent/ES531995A0/es
Publication of ES8505542A1 publication Critical patent/ES8505542A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
ES531995A 1983-05-06 1984-04-27 Formulacion parenteral de nimodipina, un procedimiento para su preparacion, asi como su empleo en la lucha contra enfermedades Expired ES8505542A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833316510 DE3316510A1 (de) 1983-05-06 1983-05-06 Parenterale formulierung von nimodipin, ein verfahren zu ihrer herstellung sowie ihre verwendung bei der bekaempfung von erkrankungen

Publications (2)

Publication Number Publication Date
ES531995A0 ES531995A0 (es) 1985-06-01
ES8505542A1 true ES8505542A1 (es) 1985-06-01

Family

ID=6198265

Family Applications (1)

Application Number Title Priority Date Filing Date
ES531995A Expired ES8505542A1 (es) 1983-05-06 1984-04-27 Formulacion parenteral de nimodipina, un procedimiento para su preparacion, asi como su empleo en la lucha contra enfermedades

Country Status (19)

Country Link
US (1) US5114956A (enExample)
EP (1) EP0126315B1 (enExample)
JP (1) JPS59206305A (enExample)
KR (1) KR920000306B1 (enExample)
AT (1) ATE24835T1 (enExample)
AU (1) AU562293B2 (enExample)
BE (1) BE899564A (enExample)
CA (1) CA1220424A (enExample)
DE (2) DE3316510A1 (enExample)
DK (1) DK164148C (enExample)
ES (1) ES8505542A1 (enExample)
FR (1) FR2545354B1 (enExample)
GR (1) GR81609B (enExample)
HK (1) HK75889A (enExample)
IL (1) IL71744A (enExample)
IT (1) IT1181804B (enExample)
PT (1) PT78542B (enExample)
SG (1) SG44489G (enExample)
ZA (1) ZA843352B (enExample)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60246313A (ja) * 1984-05-22 1985-12-06 Yamanouchi Pharmaceut Co Ltd 塩酸ニカルジピンの注射剤およびその製法
FR2585574B1 (fr) * 1985-07-31 1988-09-09 Corbiere Jerome Nouvelles compositions pharmaceutiques anti-glaucomateuses a base de 1,4-dihydropyridines et leur procede d'obtention
AT387518B (de) * 1985-12-18 1989-02-10 Bayer Ag Verfahren zur herstellung von fluessigen spruehpraeparaten von dihydropyridinen
DE3544692A1 (de) * 1985-12-18 1987-06-19 Bayer Ag Dihydropyridinspray, verfahren zu seiner herstellung und seine pharmazeutische verwendung
DE3702105A1 (de) * 1987-01-24 1988-08-04 Bayer Ag Parenterale loesung
CA2011063C (en) * 1989-02-28 1999-07-06 Calum B. Macfarlane Nicardipine pharmaceutical composition for parenteral administration
RU1804845C (ru) * 1991-02-15 1993-03-30 Институт Органического Синтеза Латвийской Ан Ноотропное вещество
EP1609477B1 (en) * 1994-12-12 2011-11-09 Omeros Corporation Irrigation solution and use thereof for the perioperative inhibition of pain/inflammation and/or spasm at a vascular structure
KR100517210B1 (ko) * 1994-12-12 2006-06-07 오메로스 코포레이션 통증,염증및경련억제용관주용액
JPH10510540A (ja) 1994-12-12 1998-10-13 オメロス メディカル システムズ，インコーポレーテッド 灌注用溶液並びに疼痛、炎症及びけいれんの抑制法
US6492332B1 (en) 1995-12-12 2002-12-10 Omeros Corporation Irrigation solution and methods for inhibition of tumor cell adhesion, pain and inflammation
US6413961B1 (en) 1995-12-12 2002-07-02 Omeros Medical Systems, Inc. Irrigation solution and method for inhibition of pain and inflammation
US6136799A (en) * 1998-04-08 2000-10-24 Abbott Laboratories Cosolvent formulations
DE10142417A1 (de) * 2001-08-31 2003-03-20 Molecular And Clinical Drug Re Arzneimittel
DE10142416A1 (de) * 2001-08-31 2003-03-20 Molecular And Clinical Drug Re Verfahren zur Herstellung von Lösungen
US8034762B2 (en) * 2004-09-02 2011-10-11 Cognosci, Inc. Treatment of subarachnoid hemorrhage with Apo E analogs
CA2625862A1 (en) * 2005-10-14 2007-04-26 Transform Pharmaceuticals, Inc. Liquid pharmaceutical compositions of nimodipine
CN101431985A (zh) * 2006-04-28 2009-05-13 巴斯夫欧洲公司 在含水介质中加溶疏水活性物质的方法
EP2531548A1 (de) 2010-02-05 2012-12-12 Basf Se Verfahren zur solubilisierung von hydrophoben wirkstoffen in wässrigem medium
US8728504B2 (en) 2010-02-05 2014-05-20 Basf Se Process for solubilizing hydrophobic active ingredients in aqueous medium
EP3238709B1 (en) 2011-04-28 2020-07-01 Platform Brightworks Two, Ltd. Improved parenteral formulations of lipophilic pharmaceutical agents and methods for preparing and using the same
EP3442586B1 (en) 2016-04-13 2022-06-08 Grace Therapeutics Inc. Stable nimopidine parenteral formulation
US10092553B2 (en) 2016-04-13 2018-10-09 Nortic Holdings Inc. Stable nimodipine parenteral formulation
EP3755326A4 (en) 2018-02-22 2021-11-03 Nortic Holdings Inc. STABLE PARENTERAL FORMULATION OF NIMODIPINE
KR20250009479A (ko) 2022-05-16 2025-01-17 아카스티 파마 유.에스., 인크. 니모디핀 비경구 투여

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2117571C3 (de) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
US4154839A (en) * 1975-11-05 1979-05-15 Bayer Aktiengesellschaft 2,6-Dimethyl-3-carboxymethoxy-4-(2-nitrophenyl)-5-carbisobutoxy-1,4-dihydropyridine
DE2650013C3 (de) * 1976-10-30 1981-04-02 Bayer Ag, 5090 Leverkusen 1.4-Dihydro-2.6-dimethyl-4-(3-nitrophenyl)-3.5-pyridindicarbonsäureisopropyl-(2-propoxy-äthyl)-ester, Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel
DE2815578C2 (de) * 1978-04-11 1986-01-16 Bayer Ag, 5090 Leverkusen Neue pharmazeutische Verwendung von Nimodipin
DE2841667A1 (de) * 1978-09-25 1980-04-10 Bayer Ag Fluorhaltige 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
PT78542B (en) 1986-07-14
DK224184D0 (da) 1984-05-04
IL71744A (en) 1988-04-29
KR920000306B1 (ko) 1992-01-11
ZA843352B (en) 1984-12-24
DK224184A (da) 1984-11-07
AU2758384A (en) 1984-11-08
IL71744A0 (en) 1984-09-30
EP0126315B1 (de) 1987-01-14
ATE24835T1 (de) 1987-01-15
KR840009031A (ko) 1984-12-24
GR81609B (enExample) 1984-12-11
BE899564A (fr) 1984-11-05
CA1220424A (en) 1987-04-14
DK164148C (da) 1992-10-26
AU562293B2 (en) 1987-06-04
IT8448139A1 (it) 1985-11-04
FR2545354B1 (fr) 1986-09-26
JPS59206305A (ja) 1984-11-22
IT8448139A0 (it) 1984-05-04
ES531995A0 (es) 1985-06-01
PT78542A (en) 1984-06-01
DK164148B (da) 1992-05-18
DE3461988D1 (en) 1987-02-19
DE3316510A1 (de) 1984-11-08
SG44489G (en) 1989-11-17
FR2545354A1 (fr) 1984-11-09
US5114956A (en) 1992-05-19
IT1181804B (it) 1987-09-30
HK75889A (en) 1989-09-29
EP0126315A1 (de) 1984-11-28
JPH0422888B2 (enExample) 1992-04-20

Similar Documents

Publication Publication Date Title
ES8505542A1 (es) Formulacion parenteral de nimodipina, un procedimiento para su preparacion, asi como su empleo en la lucha contra enfermedades
DE3577442D1 (de) Substituierte propanphosphonigsaeure-verbindungen.
CA2010909A1 (en) Storage-stable whitener formulation
ES2150989T3 (es) Nuevos derivados de quinoxalinadiona, su preparacion y empleo en medicamentos.
MX17808A (es) Nuevos derivados de artemisinina,procedimiento para su preparacion y su uso como agentes antiprosoos
ATE93678T1 (de) Mikrobiozide jodzusammensetzung.
ES8800605A1 (es) Procedimiento para preparar una composicion coloeada de utilidad en cirugia ocular.
FR2767525B1 (fr) Derives biphenyliques substitues par un radical aromatique ou heteroaromatique et compositions pharmaceutiques et cosmetiques les contenant
DE3260099D1 (en) Antifungal compositions with a higher rate of the drug release as a stick
ATE120611T1 (de) Pflanzenschutz-mikroemulsionszusammensetzung.
BG50483A3 (bg) Хербициден състав и метод за борба с нежелана растителност
ES2051939T3 (es) Heteroaromatos fenoxialquilsubstituidos, procedimientos para su obtencion y su empleo para la lucha contra las pestes.
JPS5750914A (en) Betamethasone external pharmaceutical
ES2093651T3 (es) Purinas sustituidas, procedimiento para su preparacion asi como su empleo como agentes antiviricos.
ATE77532T1 (de) Fungizide zusammensetzungen.
IT7826201A0 (it) Derivati dell'etere difenilico, procedimento per preparare glistessi e composizioni erbicide contenenti gli stessi.
ES2102837T3 (es) 4-amino-2-(hetero)aril-butanamidas utiles como antagonistas de los receptores de 5-ht1a.
IT1215340B (it) Derivati di esteri dell'acido immidazol-1-il-carbossilico, procedimenti per la loro preparazione e composizioni fungicide che contengono il derivato come componente attivo.
JPS537697A (en) 3-phenylhydantoic acid derivatives, their preparation and nonmedical fungicides containing the same as active constituents
NO900951L (no) Pulversammensetning for aa lage munnvann.
JPS5350328A (en) Composition for herbicides
IT8026436A0 (it) Derivati 2,5-dialchilfenilureici processo per la loro preparazione, composizioni erbicide che licontengono e metodo per combattere malerbe con il loro impiego.
MX9204118A (es) 2-amino-1,3,4,-tiadiazoles aminoalquilsustituidos, su preparacion y su empleo.
MX9204116A (es) 2-amino-5-mercaptotiadizoles, aminoalquilsustituidos su preparacion y su empleo.
KR830000512A (ko) 살진균제(殺眞菌劑)조성물

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20050307