DK164148C - Parenteralt praeparat af nimodipin og fremgangsmaade til dets fremstilling - Google Patents

Parenteralt praeparat af nimodipin og fremgangsmaade til dets fremstilling

Info

Publication number
DK164148C
DK164148C DK224184A DK224184A DK164148C DK 164148 C DK164148 C DK 164148C DK 224184 A DK224184 A DK 224184A DK 224184 A DK224184 A DK 224184A DK 164148 C DK164148 C DK 164148C
Authority
DK
Denmark
Prior art keywords
weight
preparation
per cent
nimodipin
procedure
Prior art date
Application number
DK224184A
Other languages
Danish (da)
English (en)
Other versions
DK224184D0 (da
DK224184A (da
DK164148B (da
Inventor
Dieter Hoff
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK224184D0 publication Critical patent/DK224184D0/da
Publication of DK224184A publication Critical patent/DK224184A/da
Publication of DK164148B publication Critical patent/DK164148B/da
Application granted granted Critical
Publication of DK164148C publication Critical patent/DK164148C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
DK224184A 1983-05-06 1984-05-04 Parenteralt praeparat af nimodipin og fremgangsmaade til dets fremstilling DK164148C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19833316510 DE3316510A1 (de) 1983-05-06 1983-05-06 Parenterale formulierung von nimodipin, ein verfahren zu ihrer herstellung sowie ihre verwendung bei der bekaempfung von erkrankungen
DE3316510 1983-05-06

Publications (4)

Publication Number Publication Date
DK224184D0 DK224184D0 (da) 1984-05-04
DK224184A DK224184A (da) 1984-11-07
DK164148B DK164148B (da) 1992-05-18
DK164148C true DK164148C (da) 1992-10-26

Family

ID=6198265

Family Applications (1)

Application Number Title Priority Date Filing Date
DK224184A DK164148C (da) 1983-05-06 1984-05-04 Parenteralt praeparat af nimodipin og fremgangsmaade til dets fremstilling

Country Status (19)

Country Link
US (1) US5114956A (enExample)
EP (1) EP0126315B1 (enExample)
JP (1) JPS59206305A (enExample)
KR (1) KR920000306B1 (enExample)
AT (1) ATE24835T1 (enExample)
AU (1) AU562293B2 (enExample)
BE (1) BE899564A (enExample)
CA (1) CA1220424A (enExample)
DE (2) DE3316510A1 (enExample)
DK (1) DK164148C (enExample)
ES (1) ES8505542A1 (enExample)
FR (1) FR2545354B1 (enExample)
GR (1) GR81609B (enExample)
HK (1) HK75889A (enExample)
IL (1) IL71744A (enExample)
IT (1) IT1181804B (enExample)
PT (1) PT78542B (enExample)
SG (1) SG44489G (enExample)
ZA (1) ZA843352B (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60246313A (ja) * 1984-05-22 1985-12-06 Yamanouchi Pharmaceut Co Ltd 塩酸ニカルジピンの注射剤およびその製法
FR2585574B1 (fr) * 1985-07-31 1988-09-09 Corbiere Jerome Nouvelles compositions pharmaceutiques anti-glaucomateuses a base de 1,4-dihydropyridines et leur procede d'obtention
DE3544692A1 (de) * 1985-12-18 1987-06-19 Bayer Ag Dihydropyridinspray, verfahren zu seiner herstellung und seine pharmazeutische verwendung
AT387518B (de) * 1985-12-18 1989-02-10 Bayer Ag Verfahren zur herstellung von fluessigen spruehpraeparaten von dihydropyridinen
DE3702105A1 (de) * 1987-01-24 1988-08-04 Bayer Ag Parenterale loesung
CA2011063C (en) * 1989-02-28 1999-07-06 Calum B. Macfarlane Nicardipine pharmaceutical composition for parenteral administration
RU1804845C (ru) * 1991-02-15 1993-03-30 Институт Органического Синтеза Латвийской Ан Ноотропное вещество
KR100517210B1 (ko) * 1994-12-12 2006-06-07 오메로스 코포레이션 통증,염증및경련억제용관주용액
RU2180852C2 (ru) * 1994-12-12 2002-03-27 Омерос Медикл Системс, Инк. Ингибирующий раствор и способ подавления боли, воспаления или спазма
JPH10510540A (ja) * 1994-12-12 1998-10-13 オメロス メディカル システムズ，インコーポレーテッド 灌注用溶液並びに疼痛、炎症及びけいれんの抑制法
US6492332B1 (en) 1995-12-12 2002-12-10 Omeros Corporation Irrigation solution and methods for inhibition of tumor cell adhesion, pain and inflammation
US6413961B1 (en) 1995-12-12 2002-07-02 Omeros Medical Systems, Inc. Irrigation solution and method for inhibition of pain and inflammation
US6136799A (en) * 1998-04-08 2000-10-24 Abbott Laboratories Cosolvent formulations
DE10142416A1 (de) * 2001-08-31 2003-03-20 Molecular And Clinical Drug Re Verfahren zur Herstellung von Lösungen
DE10142417A1 (de) * 2001-08-31 2003-03-20 Molecular And Clinical Drug Re Arzneimittel
US8034762B2 (en) 2004-09-02 2011-10-11 Cognosci, Inc. Treatment of subarachnoid hemorrhage with Apo E analogs
JP2009511594A (ja) * 2005-10-14 2009-03-19 トランスフオーム・フアーマシユーチカルズ・インコーポレーテツド ニモジピンの液体製薬学的組成物
EP2015730A1 (de) * 2006-04-28 2009-01-21 Basf Se Verfahren zur solubilisierung von hydrophoben wirkstoffen in wässrigem medium
US8728504B2 (en) 2010-02-05 2014-05-20 Basf Se Process for solubilizing hydrophobic active ingredients in aqueous medium
CN102741327B (zh) 2010-02-05 2014-11-05 巴斯夫欧洲公司 在水溶液中加溶疏水性活性成分的方法
EP3238709B1 (en) 2011-04-28 2020-07-01 Platform Brightworks Two, Ltd. Improved parenteral formulations of lipophilic pharmaceutical agents and methods for preparing and using the same
KR20190005871A (ko) * 2016-04-13 2019-01-16 노틱 홀딩스 잉크. 안정한 니모디핀 비경구 제제
US10092553B2 (en) 2016-04-13 2018-10-09 Nortic Holdings Inc. Stable nimodipine parenteral formulation
WO2019165066A2 (en) 2018-02-22 2019-08-29 Nortic Holdings Inc. Stable nimodipine parenteral formulation
WO2023224851A1 (en) 2022-05-16 2023-11-23 Acasti Pharma U.S., Inc. Nimodipine parenteral administration
CN117502433A (zh) * 2023-11-08 2024-02-06 中国科学院海洋研究所 一种水母刺丝囊存放保护剂及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2117571C3 (de) * 1971-04-10 1979-10-11 Bayer Ag, 5090 Leverkusen Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
US4154839A (en) * 1975-11-05 1979-05-15 Bayer Aktiengesellschaft 2,6-Dimethyl-3-carboxymethoxy-4-(2-nitrophenyl)-5-carbisobutoxy-1,4-dihydropyridine
DE2650013C3 (de) * 1976-10-30 1981-04-02 Bayer Ag, 5090 Leverkusen 1.4-Dihydro-2.6-dimethyl-4-(3-nitrophenyl)-3.5-pyridindicarbonsäureisopropyl-(2-propoxy-äthyl)-ester, Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel
DE2815578C2 (de) * 1978-04-11 1986-01-16 Bayer Ag, 5090 Leverkusen Neue pharmazeutische Verwendung von Nimodipin
DE2841667A1 (de) * 1978-09-25 1980-04-10 Bayer Ag Fluorhaltige 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
AU2758384A (en) 1984-11-08
KR840009031A (ko) 1984-12-24
KR920000306B1 (ko) 1992-01-11
ES531995A0 (es) 1985-06-01
PT78542A (en) 1984-06-01
CA1220424A (en) 1987-04-14
IL71744A (en) 1988-04-29
IT1181804B (it) 1987-09-30
FR2545354B1 (fr) 1986-09-26
DK224184D0 (da) 1984-05-04
HK75889A (en) 1989-09-29
AU562293B2 (en) 1987-06-04
GR81609B (enExample) 1984-12-11
FR2545354A1 (fr) 1984-11-09
EP0126315B1 (de) 1987-01-14
PT78542B (en) 1986-07-14
IT8448139A0 (it) 1984-05-04
IL71744A0 (en) 1984-09-30
SG44489G (en) 1989-11-17
ZA843352B (en) 1984-12-24
DE3461988D1 (en) 1987-02-19
JPS59206305A (ja) 1984-11-22
DK224184A (da) 1984-11-07
EP0126315A1 (de) 1984-11-28
ATE24835T1 (de) 1987-01-15
DK164148B (da) 1992-05-18
BE899564A (fr) 1984-11-05
ES8505542A1 (es) 1985-06-01
US5114956A (en) 1992-05-19
JPH0422888B2 (enExample) 1992-04-20
DE3316510A1 (de) 1984-11-08
IT8448139A1 (it) 1985-11-04

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Legal Events

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