DE69614833D1 - Entzündungshemmende benzoesäurederivate - Google Patents
Entzündungshemmende benzoesäurederivateInfo
- Publication number
- DE69614833D1 DE69614833D1 DE69614833T DE69614833T DE69614833D1 DE 69614833 D1 DE69614833 D1 DE 69614833D1 DE 69614833 T DE69614833 T DE 69614833T DE 69614833 T DE69614833 T DE 69614833T DE 69614833 D1 DE69614833 D1 DE 69614833D1
- Authority
- DE
- Germany
- Prior art keywords
- heterocyclic
- carbocyclic
- alkenylene
- halo
- trifluoromethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
- C07C45/292—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with chromium derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/33—Polycyclic acids
- C07C63/331—Polycyclic acids with all carboxyl groups bound to non-condensed rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
- C07C63/66—Polycyclic acids with unsaturation outside the aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
- C07C69/92—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with etherified hydroxyl groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/389,662 US5530157A (en) | 1995-02-16 | 1995-02-16 | Anti-inflammatory benzoic acid derivatives |
PCT/US1996/001997 WO1996025383A1 (en) | 1995-02-16 | 1996-02-15 | Anti-inflammatory benzoic acid derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69614833D1 true DE69614833D1 (de) | 2001-10-04 |
DE69614833T2 DE69614833T2 (de) | 2002-04-25 |
Family
ID=23539191
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69614833T Expired - Lifetime DE69614833T2 (de) | 1995-02-16 | 1996-02-15 | Entzündungshemmende benzoesäurederivate |
Country Status (8)
Country | Link |
---|---|
US (1) | US5530157A (de) |
EP (1) | EP0809622B1 (de) |
JP (1) | JPH11500434A (de) |
AT (1) | ATE204846T1 (de) |
CA (1) | CA2212631A1 (de) |
DE (1) | DE69614833T2 (de) |
ES (1) | ES2163617T3 (de) |
WO (1) | WO1996025383A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6270766B1 (en) * | 1992-10-08 | 2001-08-07 | The Kennedy Institute Of Rheumatology | Anti-TNF antibodies and methotrexate in the treatment of arthritis and crohn's disease |
GB9420557D0 (en) * | 1994-10-12 | 1994-11-30 | Zeneca Ltd | Aromatic compounds |
TW434240B (en) * | 1995-06-20 | 2001-05-16 | Zeneca Ltd | Aromatic compounds, preparation thereof and pharmaceutical composition comprising same |
TW502026B (en) * | 1995-06-20 | 2002-09-11 | Zeneca Ltd | Aromatic compounds useful as antagonists of e-type prostaglandins, processes for the preparation thereof, pharmaceutical compositions comprising the compounds, and intermediates |
DE69635254T2 (de) * | 1995-07-07 | 2006-07-13 | Astrazeneca Ab | Ortho-substituierte aromatische Verbindungen, die drei (Het)aryl-Ringe enthalten, deren Herstellung und deren Verwendung als Prostaglandin-E2-(PGE2)-Antagonisten |
US6331640B1 (en) | 1998-10-13 | 2001-12-18 | Hoffmann-La Roche Inc. | Diaminopropionic acid derivatives |
AU2002319677B8 (en) * | 2001-07-23 | 2009-04-30 | Atwater Management Llc | Cytoprotective compounds, pharmaceutical and cosmetic formulations, and methods |
DE10301917B4 (de) * | 2003-01-17 | 2007-02-01 | Gerhard Saalmann | Verwendung von Substanzen der Porphyrinsynthese bei der Phototherapie von Haut- oder Gelenkerkrankungen des Menschen oder von Säugetieren |
ES2530235T3 (es) | 2003-02-13 | 2015-02-27 | Wellstat Therapeutics Corporation | Compuestos para el tratamiento de trastornos metabólicos |
WO2005116010A1 (en) * | 2004-05-26 | 2005-12-08 | Merck Frosst Canada Ltd. | Ep4 receptor agonist, compositions and methods thereof |
GB2450016B (en) * | 2006-02-03 | 2010-10-20 | Sumitomo Chemical Co | Process for producing aromatic compounds by transition metal complex-mediated ortho-alkenylation |
US20130331452A1 (en) | 2010-09-08 | 2013-12-12 | Wellstat Therapeutics Corporation | Benzoic acid compounds for reducing uric acid |
US10125843B2 (en) | 2016-10-20 | 2018-11-13 | Minus K. Technology, Inc. | Horizontal-motion vibration isolator |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR96234E (fr) * | 1968-12-31 | 1972-05-19 | Inst Francais Du Petrole | Nouveaux monomeres précruseurs de polyimides aromatiques, leur procédé de polycondensation et les résines qui en résultent. |
JPH0730007B2 (ja) * | 1985-07-23 | 1995-04-05 | 旭硝子株式会社 | ジフルオロシアノ化合物及びそれを含有する液晶組成物 |
GB8810094D0 (en) * | 1988-04-28 | 1988-06-02 | Plessey Co Plc | Asychronous time division network |
JPH0229822A (ja) * | 1988-07-20 | 1990-01-31 | Toshiba Corp | コンピュータシステム |
FR2676439B1 (fr) * | 1991-05-13 | 1994-10-28 | Cird Galderma | Nouveaux composes bi-aromatiques derives d'un motif salicylique, leur procede de preparation et leur utilisation en medecine humaine et veterinaire ainsi qu'en cosmetique. |
US5326898A (en) * | 1992-02-11 | 1994-07-05 | Allergan, Inc. | Substituted phenylethenyl compounds having retinoid-like biological activity |
JPH05339204A (ja) * | 1992-06-05 | 1993-12-21 | New Japan Chem Co Ltd | 芳香族ジカルボン酸の製造方法 |
CA2137997A1 (en) * | 1994-01-03 | 1995-07-04 | John E. Starrett, Jr. | Retinoid-like compounds |
-
1995
- 1995-02-16 US US08/389,662 patent/US5530157A/en not_active Expired - Lifetime
-
1996
- 1996-02-15 EP EP96906437A patent/EP0809622B1/de not_active Expired - Lifetime
- 1996-02-15 ES ES96906437T patent/ES2163617T3/es not_active Expired - Lifetime
- 1996-02-15 WO PCT/US1996/001997 patent/WO1996025383A1/en active IP Right Grant
- 1996-02-15 AT AT96906437T patent/ATE204846T1/de not_active IP Right Cessation
- 1996-02-15 JP JP8525115A patent/JPH11500434A/ja not_active Ceased
- 1996-02-15 DE DE69614833T patent/DE69614833T2/de not_active Expired - Lifetime
- 1996-02-15 CA CA002212631A patent/CA2212631A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP0809622A1 (de) | 1997-12-03 |
ES2163617T3 (es) | 2002-02-01 |
DE69614833T2 (de) | 2002-04-25 |
CA2212631A1 (en) | 1996-08-22 |
ATE204846T1 (de) | 2001-09-15 |
JPH11500434A (ja) | 1999-01-12 |
EP0809622A4 (de) | 1998-07-08 |
US5530157A (en) | 1996-06-25 |
EP0809622B1 (de) | 2001-08-29 |
WO1996025383A1 (en) | 1996-08-22 |
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