ES8505253A1 - Un procedimiento para preparar un organismo unicelular que tiene una secuencia de adn que codifica un plipeptid0 que tiene un determinante inmunorreactivo u antigeno de una glicoproteina de virus de herpes simplex. - Google Patents
Un procedimiento para preparar un organismo unicelular que tiene una secuencia de adn que codifica un plipeptid0 que tiene un determinante inmunorreactivo u antigeno de una glicoproteina de virus de herpes simplex.Info
- Publication number
- ES8505253A1 ES8505253A1 ES529225A ES529225A ES8505253A1 ES 8505253 A1 ES8505253 A1 ES 8505253A1 ES 529225 A ES529225 A ES 529225A ES 529225 A ES529225 A ES 529225A ES 8505253 A1 ES8505253 A1 ES 8505253A1
- Authority
- ES
- Spain
- Prior art keywords
- hsv
- herpes simplex
- production
- viral proteins
- simplex viral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 208000009889 Herpes Simplex Diseases 0.000 title 1
- 108010067390 Viral Proteins Proteins 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 241000700588 Human alphaherpesvirus 1 Species 0.000 abstract 2
- 102000003886 Glycoproteins Human genes 0.000 abstract 1
- 108090000288 Glycoproteins Proteins 0.000 abstract 1
- 241000701074 Human alphaherpesvirus 2 Species 0.000 abstract 1
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- 241000700584 Simplexvirus Species 0.000 abstract 1
- 238000010367 cloning Methods 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR UN ORGANISMO UNICELULAR QUE TIENE UNA SECUENCIA DE ADN QUE CODIFICA UN POLIPEPTIDO QUE TIENE UN DETERMINANTE INMUNORREACTIVO Y ANTIGENO DE UNA GLICOPROTEINA DEL VIRUS DE HERPES SIMPLEX.CONSISTE EN INTRODUCIR UN VECTOR RECOMBINANTE EN UN ORGANISMO UNICELULAR COMPRENDIENDO DICHO VECTOR RECOMBINANTE UNA SECUENCIA DE ADN QUE CODIFICA UN POLIPEPTIDO QUE TIENE UN DETERMINANTE INMUNORREACTIVO Y ANTIGENO DE UNA GLICOPROTEINA DE VIRUS DE HERPEX SIMPLEX. DICHA SECUENCIA DE ADN ES CAPAZ DE REPLICARSE, TRANSCRIBIRSE Y TRADUCIRSE EN EL ORGANISMO UNICELULAR.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/400,028 US4818694A (en) | 1982-07-20 | 1982-07-20 | Production of herpes simplex viral protein |
US43636882A | 1982-10-25 | 1982-10-25 | |
US06/510,551 US4891315A (en) | 1982-10-25 | 1983-07-06 | Production of herpes simplex viral porteins |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8505253A1 true ES8505253A1 (es) | 1985-05-16 |
ES529225A0 ES529225A0 (es) | 1985-05-16 |
Family
ID=27410368
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES524245A Granted ES524245A0 (es) | 1982-07-20 | 1983-07-19 | Procedimiento para obtener un polipeptido |
ES529225A Granted ES529225A0 (es) | 1982-07-20 | 1984-01-27 | Un procedimiento para preparar un organismo unicelular que tiene una secuencia de adn que codifica un plipeptid0 que tiene un determinante inmunorreactivo u antigeno de una glicoproteina de virus de herpes simplex. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES524245A Granted ES524245A0 (es) | 1982-07-20 | 1983-07-19 | Procedimiento para obtener un polipeptido |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0101655B1 (es) |
CA (1) | CA1295561C (es) |
DE (1) | DE3382072D1 (es) |
DK (1) | DK333183A (es) |
ES (2) | ES524245A0 (es) |
FI (1) | FI83974C (es) |
GR (1) | GR78647B (es) |
IE (1) | IE56902B1 (es) |
IL (1) | IL69269A (es) |
NO (1) | NO172855C (es) |
NZ (1) | NZ204948A (es) |
PH (1) | PH21239A (es) |
PL (1) | PL150654B1 (es) |
PT (1) | PT77014B (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3228501A1 (de) * | 1982-07-30 | 1984-02-02 | Behringwerke Ag, 3550 Marburg | Verfahren zur herstellung eines herpes-antigens, dazu geeignetes mittel sowie verfahren zu seiner herstellung und die verwendung dieses antigens |
DK305784A (da) * | 1983-06-23 | 1984-12-24 | Stanley Person | Ikke-glycosyleret aminosyrekaede af glycoprotein b fra herpes virus type 1 og 2 |
US7264817B1 (en) | 1983-08-30 | 2007-09-04 | Genentech, Inc. | Immunogenic composition based on a truncated derivative of a membrane bound protein and process for making it |
NZ209308A (en) * | 1983-08-30 | 1991-08-27 | Genentech Inc | Vaccine against hsv involving a truncated membrane-free derivative of a membrane-bound protein |
NZ209307A (en) * | 1983-08-30 | 1990-07-26 | Genentech Inc | Diagnostic product: antigenic peptide produced by recombinant dna techniques |
JPS615786A (ja) * | 1984-06-19 | 1986-01-11 | Chemo Sero Therapeut Res Inst | 単純ヘルペスウイルス遺伝子を組込んだ組換えdna、形質転換動物細胞および単純ヘルペスウイルス蛋白質の製法 |
DE3582200D1 (de) * | 1984-07-20 | 1991-04-25 | Chemo Sero Therapeut Res Inst | Rekombinante dns, enthaltend ein herpes-simplex-virus-gen oder ein fragment davon, hefe transformiert mit dieser rekombinanten dns und verfahren zur herstellung von herpes-simplex-virus-proteinen. |
US4659568A (en) * | 1985-02-27 | 1987-04-21 | American Cyanamid Company | Process for solubilization, purification and characterization of protein from insoluble protein aggregates or complexes and compositions of matter therefrom |
DE3510734A1 (de) * | 1985-03-25 | 1986-09-25 | Behringwerke Ag, 3550 Marburg | Verfahren zur herstellung eines fuer herpes simplex virus typ 2 spezifischen antigens, dazu geeignetes mittel und verwendung dieses antigens |
JPH0668B2 (ja) * | 1985-08-30 | 1994-01-05 | 財団法人化学及血清療法研究所 | 単純ヘルペスウイルス遺伝子が組込まれた組換えプラスミド |
EP0471778A1 (en) * | 1989-05-12 | 1992-02-26 | Ciba Corning Diagnostics Corp. | Herpes simplex virus type 2-glycoprotein g proteins and polypeptides |
US5149532A (en) * | 1989-11-01 | 1992-09-22 | Cedars Sinai Medical Center | Method of vaccine or toxoid preparation and immunization by colonization with recombinant microorganisms |
AU2004274430A1 (en) | 2003-09-12 | 2005-03-31 | Antigenics, Inc. | Vaccine for treatment and prevention of herpes simplex virus infection |
CN110938604B (zh) * | 2014-03-03 | 2024-04-05 | 阿尔伯特爱因斯坦医学院 | 重组单纯疱疹病毒2(hsv-2)疫苗载体 |
US10918712B2 (en) | 2014-03-03 | 2021-02-16 | Albert Einstein College Of Medicine | Passive transfer of immunity using recombinant herpes simplex virus 2 (HSV-2) vaccine vectors |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3228501A1 (de) * | 1982-07-30 | 1984-02-02 | Behringwerke Ag, 3550 Marburg | Verfahren zur herstellung eines herpes-antigens, dazu geeignetes mittel sowie verfahren zu seiner herstellung und die verwendung dieses antigens |
-
1983
- 1983-07-11 PT PT77014A patent/PT77014B/pt unknown
- 1983-07-18 IL IL69269A patent/IL69269A/xx not_active IP Right Cessation
- 1983-07-18 GR GR71958A patent/GR78647B/el unknown
- 1983-07-18 CA CA000432633A patent/CA1295561C/en not_active Expired - Lifetime
- 1983-07-18 PH PH29243A patent/PH21239A/en unknown
- 1983-07-19 DE DE8383401476T patent/DE3382072D1/de not_active Expired - Fee Related
- 1983-07-19 NZ NZ204948A patent/NZ204948A/en unknown
- 1983-07-19 NO NO832626A patent/NO172855C/no not_active IP Right Cessation
- 1983-07-19 IE IE1690/83A patent/IE56902B1/en not_active IP Right Cessation
- 1983-07-19 FI FI832632A patent/FI83974C/fi not_active IP Right Cessation
- 1983-07-19 EP EP83401476A patent/EP0101655B1/en not_active Expired
- 1983-07-19 ES ES524245A patent/ES524245A0/es active Granted
- 1983-07-19 DK DK333183A patent/DK333183A/da unknown
- 1983-07-20 PL PL1983243134A patent/PL150654B1/pl unknown
-
1984
- 1984-01-27 ES ES529225A patent/ES529225A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
IE56902B1 (en) | 1992-01-29 |
GR78647B (es) | 1984-09-27 |
EP0101655A2 (en) | 1984-02-29 |
FI832632A0 (fi) | 1983-07-19 |
DK333183D0 (da) | 1983-07-19 |
NO832626L (no) | 1984-01-23 |
PH21239A (en) | 1987-08-21 |
PT77014A (en) | 1983-08-01 |
EP0101655B1 (en) | 1991-01-02 |
FI83974C (fi) | 1991-09-25 |
DK333183A (da) | 1984-01-21 |
ES8504254A1 (es) | 1985-04-01 |
FI832632A (fi) | 1984-01-21 |
FI83974B (fi) | 1991-06-14 |
PT77014B (en) | 1986-01-24 |
NO172855B (no) | 1993-06-07 |
EP0101655A3 (en) | 1985-12-18 |
IL69269A0 (en) | 1983-11-30 |
IL69269A (en) | 1989-12-15 |
ES524245A0 (es) | 1985-04-01 |
IE831690L (en) | 1984-01-20 |
NO172855C (no) | 1993-09-15 |
ES529225A0 (es) | 1985-05-16 |
PL243134A1 (en) | 1984-08-13 |
NZ204948A (en) | 1987-10-30 |
DE3382072D1 (de) | 1991-02-07 |
PL150654B1 (en) | 1990-06-30 |
CA1295561C (en) | 1992-02-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19980302 |