ES8407095A1 - Un procedimiento de preparar un liposoma recubierto que contiene ubidecarenona. - Google Patents
Un procedimiento de preparar un liposoma recubierto que contiene ubidecarenona.Info
- Publication number
- ES8407095A1 ES8407095A1 ES522512A ES522512A ES8407095A1 ES 8407095 A1 ES8407095 A1 ES 8407095A1 ES 522512 A ES522512 A ES 522512A ES 522512 A ES522512 A ES 522512A ES 8407095 A1 ES8407095 A1 ES 8407095A1
- Authority
- ES
- Spain
- Prior art keywords
- ubidecarenone
- coated
- containing liposome
- liposome
- kidneys
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 title abstract 4
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 title abstract 4
- 235000017471 coenzyme Q10 Nutrition 0.000 title abstract 4
- 239000002502 liposome Substances 0.000 title abstract 4
- 229960004747 ubidecarenone Drugs 0.000 title abstract 4
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 210000003734 kidney Anatomy 0.000 abstract 1
- 210000004072 lung Anatomy 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- -1 polysaccharide fatty acid ester Chemical class 0.000 abstract 1
- 210000000952 spleen Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR UN LIPOSOMA RECUBIERTO QUE CONTENGA UBIDECARENONA.CONSISTE EN MEZCLAR UNA DISPERSION ACUOSA DE LIPOSOMA QUE CONTENGA UBIDECARENONA, CON UNA SOLUCION EN LA QUE UNO O MAS ESTERES DE ACIDO GRASO Y POLISACARIDO ESTEN DISPERSADOS EN UNA SOLUCION FISIOLOGICA, PARA OBTENER UNA DISPERSION ACUOSA DE LIPOSOMA REVESTIDO QUE CONTIENE UBIDECARENONA. A CONTINUACION, SI ES NECESARIO, SE LIOFILIZA LA DISPERSION ACUOSA PARA PREPARAR LA SUSTANCIA RECUBIERTA EN UN ESTADO PULVERULENTO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP57082993A JPS58201711A (ja) | 1982-05-19 | 1982-05-19 | ユビデカレノン含有リポソ−ム被覆体 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES522512A0 ES522512A0 (es) | 1984-09-01 |
ES8407095A1 true ES8407095A1 (es) | 1984-09-01 |
Family
ID=13789741
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES522512A Expired ES8407095A1 (es) | 1982-05-19 | 1983-05-18 | Un procedimiento de preparar un liposoma recubierto que contiene ubidecarenona. |
Country Status (8)
Country | Link |
---|---|
US (1) | US4636381A (es) |
EP (1) | EP0094692B1 (es) |
JP (1) | JPS58201711A (es) |
KR (1) | KR840004512A (es) |
AT (1) | ATE21625T1 (es) |
CA (1) | CA1214392A (es) |
DE (1) | DE3365604D1 (es) |
ES (1) | ES8407095A1 (es) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH661438A5 (it) * | 1984-04-09 | 1987-07-31 | Seuref Ag | Composizioni farmaceutiche ad azione antianossica e metabolica cerebrale. |
US4880635B1 (en) * | 1984-08-08 | 1996-07-02 | Liposome Company | Dehydrated liposomes |
JPS61112021A (ja) * | 1984-11-06 | 1986-05-30 | Dai Ichi Seiyaku Co Ltd | 脂質膜構造体 |
JPH01501153A (ja) * | 1986-10-23 | 1989-04-20 | アルバル・エッセ・ピ・ア | ユビデカレノン類を含有する化粧品 |
US5320906A (en) * | 1986-12-15 | 1994-06-14 | Vestar, Inc. | Delivery vehicles with amphiphile-associated active ingredient |
JPS63313724A (ja) * | 1987-06-16 | 1988-12-21 | Eisai Co Ltd | シアル酸修飾多糖被覆リポソ−ム |
US5705187A (en) * | 1989-12-22 | 1998-01-06 | Imarx Pharmaceutical Corp. | Compositions of lipids and stabilizing materials |
US6461593B1 (en) * | 1992-02-19 | 2002-10-08 | Biomedical And Clinical Research | Therapy with coenzyme Q10 to reduce subgingival microorganisms in patients with periodontal disease |
DE4433101A1 (de) * | 1994-09-16 | 1996-03-21 | Bauer Kurt Heinz Prof Dr | Wasserlösliche Dextranfettsäureester und ihre Verwendung als Solubilisatoren |
JP2000502087A (ja) * | 1995-12-15 | 2000-02-22 | ナショナル リサーチ カウンシル オブ カナダ | アジュバンドおよび送達賦形剤としての、アーケオソーム類、補酵素q▲下10▼を含有するアーケオソーム類、および補酵素q▲下10▼を含有する他の種類のリポソーム類 |
US5891465A (en) * | 1996-05-14 | 1999-04-06 | Biozone Laboratories, Inc. | Delivery of biologically active material in a liposomal formulation for administration into the mouth |
EP1009383A1 (en) * | 1997-09-04 | 2000-06-21 | Biozone Laboratories, Inc. | Oral liposomal delivery system |
US20010003580A1 (en) | 1998-01-14 | 2001-06-14 | Poh K. Hui | Preparation of a lipid blend and a phospholipid suspension containing the lipid blend |
BR0007542B1 (pt) * | 1999-01-15 | 2010-04-06 | processo para preparar um amido hidrofóbico, amido hidrofóbico, gel reversìvel, e, uso de um amido hidrofóbico. | |
US6710038B1 (en) | 1999-12-14 | 2004-03-23 | Kibun Food Chemifa Co., Ltd. | Emulsification method using propylene glycol hyaluronate |
US8252322B2 (en) * | 2003-06-03 | 2012-08-28 | Corn Products Development, Inc. | Delivery system with increased bioavailability |
CN102258503B (zh) | 2004-01-22 | 2019-08-16 | 迈阿密大学 | 局部辅酶q10制剂及其使用方法 |
JP2006137684A (ja) * | 2004-11-10 | 2006-06-01 | Nippon Fine Chem Co Ltd | リポソーム前駆体の製造方法 |
JP5140913B2 (ja) * | 2005-09-14 | 2013-02-13 | 日油株式会社 | コエンザイムq10含有化粧料用リポソーム |
CA2650825C (en) | 2006-05-02 | 2015-07-14 | University Of Miami | Topical co-enzyme q10 formulations and treatment of pain, fatigue and wounds |
CA2680825C (en) | 2007-03-22 | 2013-10-29 | Cytotech Labs, Llc | Topical formulations having enhanced bioavailability |
US20110142914A1 (en) * | 2007-12-06 | 2011-06-16 | Cytotech Labs, Llc | Inhalable compositions having enhanced bioavailability |
EP2271325A4 (en) | 2008-04-11 | 2011-11-09 | Cytotech Labs Llc | METHODS AND USE OF INDUCING APOPTOSIS IN CANCER CELLS |
WO2010021034A1 (ja) * | 2008-08-20 | 2010-02-25 | 昭和電工株式会社 | 皮膚外用剤 |
WO2010132486A2 (en) | 2009-05-11 | 2010-11-18 | Cytotech Labs, Llc | Methods for the diagnosis of oncological disorders using epimetabolic shifters, multidimensional intracellular molecules, or environmental influencers |
KR101907411B1 (ko) | 2010-03-12 | 2018-10-12 | 베르그 엘엘씨 | 코엔자임 Q10(CoQ10)의 정맥내 제형 및 이의 사용 방법 |
KR101933732B1 (ko) | 2011-04-04 | 2018-12-28 | 버그 엘엘씨 | 중추 신경 시스템 종양들의 치료 방법 |
MX351781B (es) | 2011-06-17 | 2017-10-30 | Berg Llc | Composiciones farmaceuticas inhalables. |
WO2014168993A1 (en) | 2013-04-08 | 2014-10-16 | Berg Llc | Treatment of cancer using coenzyme q10 combination therapies |
EP3021844B1 (en) * | 2013-07-17 | 2019-11-13 | Council of Scientific & Industrial Research | Pharmaceutical composition for the treatment of diminution of bone tissue |
ES2825083T3 (es) | 2013-09-04 | 2021-05-14 | Berg Llc | Métodos de tratamiento contra el cáncer mediante infusión continua de coenzima Q10 |
EP3634391A4 (en) | 2017-05-17 | 2021-02-24 | Berg LLC | USE OF COENZYME Q10 FORMULATIONS IN THE TREATMENT AND PREVENTION OF BUBBLE EPIDERMOLYSIS |
CN113262310A (zh) * | 2021-03-02 | 2021-08-17 | 宿迁市第一人民医院 | 一种普鲁兰多糖修饰的人参皂苷Rg3纳米结构脂质载体及其制作方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2640707C3 (de) * | 1976-09-10 | 1980-01-24 | Karl Dr.Med. 7302 Ostfildern Theurer | Verfahren zur Herstellung von Arzneipräparaten mit einem Gehalt an von im Darm resorbierbaren Protein und Peptidlösungen |
US4310505A (en) * | 1979-11-08 | 1982-01-12 | California Institute Of Technology | Lipid vesicles bearing carbohydrate surfaces as lymphatic directed vehicles for therapeutic and diagnostic substances |
FR2472384A1 (fr) * | 1979-12-27 | 1981-07-03 | Sederma Sa | Utilisation en cosmetologie de complexes naturels constitues d'ubiquinones et de phospholipides |
JPS5849311A (ja) * | 1981-09-18 | 1983-03-23 | Eisai Co Ltd | 安全なるリポソ−ムの製造法 |
-
1982
- 1982-05-19 JP JP57082993A patent/JPS58201711A/ja active Pending
-
1983
- 1983-05-18 ES ES522512A patent/ES8407095A1/es not_active Expired
- 1983-05-18 CA CA000428447A patent/CA1214392A/en not_active Expired
- 1983-05-19 AT AT83104967T patent/ATE21625T1/de not_active IP Right Cessation
- 1983-05-19 DE DE8383104967T patent/DE3365604D1/de not_active Expired
- 1983-05-19 EP EP83104967A patent/EP0094692B1/en not_active Expired
- 1983-05-19 US US06/497,255 patent/US4636381A/en not_active Expired - Fee Related
- 1983-05-19 KR KR1019830002210A patent/KR840004512A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA1214392A (en) | 1986-11-25 |
US4636381A (en) | 1987-01-13 |
DE3365604D1 (en) | 1986-10-02 |
ES522512A0 (es) | 1984-09-01 |
KR840004512A (ko) | 1984-10-22 |
JPS58201711A (ja) | 1983-11-24 |
EP0094692A1 (en) | 1983-11-23 |
EP0094692B1 (en) | 1986-08-27 |
ATE21625T1 (de) | 1986-09-15 |
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