ES8406436A1 - Procedimiento para la obtencion de derivados de la pirrolidina - Google Patents
Procedimiento para la obtencion de derivados de la pirrolidinaInfo
- Publication number
- ES8406436A1 ES8406436A1 ES527897A ES527897A ES8406436A1 ES 8406436 A1 ES8406436 A1 ES 8406436A1 ES 527897 A ES527897 A ES 527897A ES 527897 A ES527897 A ES 527897A ES 8406436 A1 ES8406436 A1 ES 8406436A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- procedure
- obtaining
- sulfur
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical class C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052717 sulfur Chemical group 0.000 abstract 2
- 239000011593 sulfur Chemical group 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
- 238000007280 thionation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Luminescent Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8220492A FR2537133A1 (fr) | 1982-12-07 | 1982-12-07 | Nouveaux derives de la (piperazinyl-1)-5 pyrrolidine, leur preparation et les medicaments qui les contiennent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES527897A0 ES527897A0 (es) | 1984-08-01 |
| ES8406436A1 true ES8406436A1 (es) | 1984-08-01 |
Family
ID=9279863
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES527897A Expired ES8406436A1 (es) | 1982-12-07 | 1983-12-07 | Procedimiento para la obtencion de derivados de la pirrolidina |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US4547504A (enExample) |
| EP (1) | EP0110795B1 (enExample) |
| JP (1) | JPS59110670A (enExample) |
| AT (1) | ATE18548T1 (enExample) |
| AU (1) | AU560075B2 (enExample) |
| BG (1) | BG40808A3 (enExample) |
| CA (1) | CA1208645A (enExample) |
| CS (1) | CS240982B2 (enExample) |
| DD (1) | DD213216A5 (enExample) |
| DE (1) | DE3362566D1 (enExample) |
| DK (1) | DK562783A (enExample) |
| ES (1) | ES8406436A1 (enExample) |
| FI (1) | FI76320C (enExample) |
| FR (1) | FR2537133A1 (enExample) |
| GR (1) | GR72855B (enExample) |
| HU (1) | HU191903B (enExample) |
| IE (1) | IE56453B1 (enExample) |
| IL (1) | IL70396A (enExample) |
| MA (1) | MA19966A1 (enExample) |
| NO (1) | NO158218C (enExample) |
| NZ (1) | NZ206498A (enExample) |
| PL (1) | PL141385B1 (enExample) |
| PT (1) | PT77774B (enExample) |
| SU (1) | SU1240359A3 (enExample) |
| ZA (1) | ZA839070B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK93087A (da) * | 1986-02-27 | 1987-08-28 | Duphar Int Res | Hidtil ukendte aryl substituerede (n-piperidinyl)methyl- og (n-piperazinyl)methylazoler med antipsykotiske egenskaber |
| ES2076253T3 (es) * | 1989-05-19 | 1995-11-01 | Hoechst Roussel Pharma | N-(ariloxialquil)-heteroarilpiperidinas y -heteroarilpiperazinas, un procedimiento para su preparacion y su uso como medicamentos. |
| US5066663A (en) * | 1990-05-21 | 1991-11-19 | Warner-Lambert Company | Substituted-hetero-cyclopentanones and cyclopentenones and derivatives thereof acting at muscarinic receptors |
| DE19540027A1 (de) * | 1995-10-27 | 1997-04-30 | Gruenenthal Gmbh | Substituierte Imidazolidin-2,4-dion-Verbindungen als pharmazeutische Wirkstoffe |
| US6897213B1 (en) | 1995-11-21 | 2005-05-24 | Warner-Lambert Company | Heterocycles as cholecystokinin (CCK) ligands |
| US5969138A (en) * | 1996-11-01 | 1999-10-19 | Mitsui Chemicals, Inc. | Pyrrolidinone derivatives |
| DE69829875T2 (de) * | 1997-10-14 | 2006-03-09 | Mitsubishi Pharma Corp. | Piperazin-verbindungen und ihre medizinische verwendung |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4247549A (en) * | 1978-12-27 | 1981-01-27 | Ici Americas Inc. | Piperazine-1-carboxylic acid esters possessing antidepressant or analgesic activity |
-
1982
- 1982-12-07 FR FR8220492A patent/FR2537133A1/fr active Granted
-
1983
- 1983-12-02 CS CS839041A patent/CS240982B2/cs unknown
- 1983-12-05 GR GR73154A patent/GR72855B/el unknown
- 1983-12-05 DD DD83257518A patent/DD213216A5/de unknown
- 1983-12-05 FI FI834453A patent/FI76320C/fi not_active IP Right Cessation
- 1983-12-05 PL PL1983244921A patent/PL141385B1/pl unknown
- 1983-12-06 US US06/558,775 patent/US4547504A/en not_active Expired - Fee Related
- 1983-12-06 MA MA20187A patent/MA19966A1/fr unknown
- 1983-12-06 DE DE8383402354T patent/DE3362566D1/de not_active Expired
- 1983-12-06 IE IE2867/83A patent/IE56453B1/xx unknown
- 1983-12-06 NZ NZ206498A patent/NZ206498A/en unknown
- 1983-12-06 DK DK562783A patent/DK562783A/da not_active Application Discontinuation
- 1983-12-06 HU HU834166A patent/HU191903B/hu unknown
- 1983-12-06 AU AU22108/83A patent/AU560075B2/en not_active Ceased
- 1983-12-06 AT AT83402354T patent/ATE18548T1/de not_active IP Right Cessation
- 1983-12-06 SU SU833673511A patent/SU1240359A3/ru active
- 1983-12-06 JP JP58229251A patent/JPS59110670A/ja active Pending
- 1983-12-06 IL IL70396A patent/IL70396A/xx not_active IP Right Cessation
- 1983-12-06 PT PT77774A patent/PT77774B/pt unknown
- 1983-12-06 ZA ZA839070A patent/ZA839070B/xx unknown
- 1983-12-06 EP EP83402354A patent/EP0110795B1/fr not_active Expired
- 1983-12-06 CA CA000442681A patent/CA1208645A/fr not_active Expired
- 1983-12-06 NO NO834481A patent/NO158218C/no unknown
- 1983-12-07 ES ES527897A patent/ES8406436A1/es not_active Expired
- 1983-12-07 BG BG063371A patent/BG40808A3/xx unknown
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