ES8704503A1 - Procedimiento para preparar sales de ciclimonio - Google Patents
Procedimiento para preparar sales de ciclimonioInfo
- Publication number
- ES8704503A1 ES8704503A1 ES547717A ES547717A ES8704503A1 ES 8704503 A1 ES8704503 A1 ES 8704503A1 ES 547717 A ES547717 A ES 547717A ES 547717 A ES547717 A ES 547717A ES 8704503 A1 ES8704503 A1 ES 8704503A1
- Authority
- ES
- Spain
- Prior art keywords
- furanyl
- substituted
- yes
- mono
- oxo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000002941 2-furyl group Chemical group O1C([*])=C([H])C([H])=C1[H] 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 206010006482 Bronchospasm Diseases 0.000 abstract 1
- -1 C12-24alkoxyalkyl Chemical group 0.000 abstract 1
- 206010015866 Extravasation Diseases 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 208000009144 Pure autonomic failure Diseases 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 230000007885 bronchoconstriction Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000036251 extravasation Effects 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 230000036543 hypotension Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 208000023569 ischemic bowel disease Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- 125000002950 monocyclic group Chemical group 0.000 abstract 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE SALES DE CICLIMONIO, DE FORMULA (I). COMPRENDE LA REACCION DE UN COMPUESTO DE FORMULA (II), CON UN COMPUESTO DE FORMULA (III), EN UN DISOLVENTE INERTE, A UNA TEMPERATURA COMPRENDIDA ENTRE 50JC Y 100JC, PARA OBTENER UN COMPUESTO DE FORMULA (I), EN LA QUE R, Y Y T PUEDEN SER VARIOS TIPOS DE RADICALES, M Y N VALEN 1 O 2, P VALE 2-8, Q VALE 0 O 1 E Y REPRESENTA HIDROGENO O UNA CARGA NEGATIVA. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA LA INHIBICION O ANTAGONISMO DEL FACTOR DE ACTIVACION DE PLAQUETAS Y EL TRATAMIENTO DE LA CONSTRICCION BRONQUIAL.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65924984A | 1984-10-10 | 1984-10-10 | |
| US75636885A | 1985-07-18 | 1985-07-18 | |
| US76611685A | 1985-08-15 | 1985-08-15 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES547717A0 ES547717A0 (es) | 1987-04-01 |
| ES8704503A1 true ES8704503A1 (es) | 1987-04-01 |
Family
ID=27418008
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES547717A Expired ES8704503A1 (es) | 1984-10-10 | 1985-10-09 | Procedimiento para preparar sales de ciclimonio |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0178261A3 (es) |
| AU (1) | AU4838485A (es) |
| DK (1) | DK460785A (es) |
| ES (1) | ES8704503A1 (es) |
| FI (1) | FI853925L (es) |
| GR (1) | GR852452B (es) |
| HU (1) | HUT42495A (es) |
| IL (1) | IL76622A0 (es) |
| PT (1) | PT81274B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3666435D1 (en) * | 1985-08-30 | 1989-11-23 | Sandoz Ag | Substituted hydroxy-heterocyclyl-alkoxy phosphinyloxy trialkylaminium hydroxide inner salt oxides, processes for their preparation and their use as pharmaceuticals |
| CN1030415A (zh) | 1987-02-20 | 1989-01-18 | 山之内制药株式会社 | 饱和的杂环碳酰胺衍生物和它的制备方法 |
| EP0312040B1 (en) * | 1987-10-13 | 1992-06-03 | J. URIACH & CIA. S.A. | 2,4-disubstituted derivatives of tetrahydrofuran |
| US4868319A (en) * | 1987-12-22 | 1989-09-19 | Sandoz Pharm. Corp. | Process for the preparation of monoalkylcarbamate group-containing compounds |
| ES2010568A6 (es) * | 1988-08-04 | 1989-11-16 | Uriach & Cia Sa J | Procedimiento para la obtencion de derivados 2,5-disustituidos de tetrahidrofurano. |
| US5231091A (en) * | 1988-12-19 | 1993-07-27 | American Cyanamid Company | Bis-arylphosphate ester antagonists of platelet activating factor |
| US4983592A (en) * | 1988-12-19 | 1991-01-08 | American Cyanamid Co. | Bis-arylphosphate ester antagonists of platelet activating factor |
| ES2013834A6 (es) * | 1989-01-30 | 1990-06-01 | Uriach & Cia Sa J | Procedimiento para la obtencion de derivados 4-sustituidos de 2-alcoxitetrahidrofurano. |
| ES2010145A6 (es) * | 1989-03-02 | 1989-10-16 | Uriach & Cia Sa J | Procedimiento para la obtencion de derivados de la 2-picolilamina. |
| HU210548B (en) * | 1990-06-19 | 1995-05-29 | Sandoz Ag | Process for preparing 2-tetrahydrofurane derivatives |
| ES2062943B1 (es) * | 1993-03-23 | 1995-11-16 | Uriach & Cia Sa J | Nuevos derivados de la (2-metil-3-piridil) cianometilpiperazinas. |
| EP0875247B1 (en) * | 1997-04-18 | 2003-05-28 | Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno | Method for controlling the plasma level of lipoproteins |
| US9670174B2 (en) * | 2013-12-19 | 2017-06-06 | Archer Daniels Midland Company | Mono- and dialkyl ethers of furan-2,5-dimethanol and (tetra-hydrofuran-2,5-diyl)dimethanol and amphiphilic derivatives thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4551532A (en) * | 1980-05-08 | 1985-11-05 | Takeda Chemical Industries, Ltd. | Ethylene glycol derivatives having anti-protozoan, anti-fungal and anti-tumor activity |
| US4427665A (en) * | 1982-05-19 | 1984-01-24 | E. R. Squibb & Sons, Inc. | Phosphinylalkanoyl substituted imino acids and their use in hypotensive compositions |
-
1985
- 1985-10-07 EP EP85810458A patent/EP0178261A3/en not_active Withdrawn
- 1985-10-08 DK DK460785A patent/DK460785A/da not_active Application Discontinuation
- 1985-10-08 AU AU48384/85A patent/AU4838485A/en not_active Abandoned
- 1985-10-09 HU HU853922A patent/HUT42495A/hu unknown
- 1985-10-09 GR GR852452A patent/GR852452B/el unknown
- 1985-10-09 PT PT81274A patent/PT81274B/pt unknown
- 1985-10-09 FI FI853925A patent/FI853925L/fi not_active IP Right Cessation
- 1985-10-09 IL IL76622A patent/IL76622A0/xx unknown
- 1985-10-09 ES ES547717A patent/ES8704503A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| PT81274A (en) | 1985-11-01 |
| ES547717A0 (es) | 1987-04-01 |
| HUT42495A (en) | 1987-07-28 |
| FI853925L (fi) | 1986-04-11 |
| IL76622A0 (en) | 1986-02-28 |
| PT81274B (en) | 1987-08-27 |
| DK460785D0 (da) | 1985-10-08 |
| EP0178261A3 (en) | 1986-12-30 |
| AU4838485A (en) | 1986-04-17 |
| GR852452B (es) | 1986-02-11 |
| EP0178261A2 (en) | 1986-04-16 |
| FI853925A0 (fi) | 1985-10-09 |
| DK460785A (da) | 1986-04-11 |
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