ES8403873A1 - Un procedimiento para la obtencion de sales de amino (e imino) acidos (alfa) w -sulfonicos n-sustituidos. - Google Patents

Un procedimiento para la obtencion de sales de amino (e imino) acidos (alfa) w -sulfonicos n-sustituidos.

Info

Publication number
ES8403873A1
ES8403873A1 ES523839A ES523839A ES8403873A1 ES 8403873 A1 ES8403873 A1 ES 8403873A1 ES 523839 A ES523839 A ES 523839A ES 523839 A ES523839 A ES 523839A ES 8403873 A1 ES8403873 A1 ES 8403873A1
Authority
ES
Spain
Prior art keywords
imino
omega
sulfonic
alpha
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES523839A
Other languages
English (en)
Other versions
ES523839A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MERAM LAB
Original Assignee
MERAM LAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MERAM LAB filed Critical MERAM LAB
Publication of ES8403873A1 publication Critical patent/ES8403873A1/es
Publication of ES523839A0 publication Critical patent/ES523839A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • C07D213/66—One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE SALES DE AMINO (E IMINO) ACIDOS A,W-SULFONICOS N-SUSTITUIDOS, DE FORMULA (I) Y (II), EN LAS QUE M ES UN METAL ALCALINO.CONSISTE EN LA REACCION DE PIRIDOXAL BASE CON UNA SAL DE UN METAL ALCALINO DEL ACIDO A,W-AMINOSULFONICO, DE FORMULA NH2-(CH2)N-SO3H. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE INERTE TAL COMO UN ALCOHOL, EN PRESENCIA DE UNA BASE, A LA TEMPERATURA AMBIENTE. EL DERIVADO IMINO SE REDUCE AL CORRESPONDIENTE DERIVADO AMINO CON UN BOROHIDRURO ALCALINO.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SUS PROPIEDADES VECTORAS CATIONICAS.
ES523839A 1982-07-05 1983-07-04 Un procedimiento para la obtencion de sales de amino (e imino) acidos (alfa) w -sulfonicos n-sustituidos. Granted ES523839A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8211768A FR2529546A1 (fr) 1982-07-05 1982-07-05 Nouveaux sels d'amino-(et imino-)acides a, o-sulfoniques n-substitues, vecteurs cationiques de haute penetration cellulaire

Publications (2)

Publication Number Publication Date
ES8403873A1 true ES8403873A1 (es) 1984-04-01
ES523839A0 ES523839A0 (es) 1984-04-01

Family

ID=9275686

Family Applications (1)

Application Number Title Priority Date Filing Date
ES523839A Granted ES523839A0 (es) 1982-07-05 1983-07-04 Un procedimiento para la obtencion de sales de amino (e imino) acidos (alfa) w -sulfonicos n-sustituidos.

Country Status (8)

Country Link
US (1) US4563470A (es)
EP (1) EP0099799B1 (es)
JP (1) JPS6055067B2 (es)
AT (1) ATE18552T1 (es)
DE (1) DE3362536D1 (es)
ES (1) ES523839A0 (es)
FR (1) FR2529546A1 (es)
PT (1) PT76970B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL146143A0 (en) * 1999-04-28 2002-07-25 Univ Kingston Compositions and methods for treating amyloidosis
US6562836B1 (en) * 1999-05-24 2003-05-13 Queen's University Of Kingston Methods and compounds for inhibiting amyloid deposits
US7414076B2 (en) * 2003-06-23 2008-08-19 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
US20070010573A1 (en) * 2003-06-23 2007-01-11 Xianqi Kong Methods and compositions for treating amyloid-related diseases
US7244764B2 (en) * 2003-06-23 2007-07-17 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
MX2007005507A (es) * 2004-11-12 2008-03-13 Neurochem Int Ltd Metodos y composiciones fluoradas para el tratamiento de padecimientos relacionados con amiloides.
AU2005310979A1 (en) * 2004-11-16 2006-06-08 Bellus Health (International) Limited Compounds for the treatment of CNS and amyloid associated diseases
CA2900876A1 (en) 2004-12-22 2006-08-17 Bhi Limited Partnership Methods and compositions for treating amyloid-related diseases
KR101443573B1 (ko) 2006-10-12 2014-11-03 비에이치아이 리미티드 파트너쉽 3-아미노-1-프로판설폰산을 전달하기 위한 방법, 화합물, 조성물 및 비히클

Also Published As

Publication number Publication date
EP0099799A1 (fr) 1984-02-01
PT76970A (fr) 1983-07-01
US4563470A (en) 1986-01-07
FR2529546B1 (es) 1985-02-08
PT76970B (fr) 1986-01-24
JPS6055067B2 (ja) 1985-12-03
ATE18552T1 (de) 1986-03-15
DE3362536D1 (en) 1986-04-17
EP0099799B1 (fr) 1986-03-12
ES523839A0 (es) 1984-04-01
FR2529546A1 (fr) 1984-01-06
JPS5921666A (ja) 1984-02-03

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980202