ATE18552T1 - Salze von alpha-amino(und imino)-saeure, omegasulfon n-substituiert, kationische vektoren mit hoher cellularer penetration und herstellungsverfahren. - Google Patents

Salze von alpha-amino(und imino)-saeure, omegasulfon n-substituiert, kationische vektoren mit hoher cellularer penetration und herstellungsverfahren.

Info

Publication number
ATE18552T1
ATE18552T1 AT83401373T AT83401373T ATE18552T1 AT E18552 T1 ATE18552 T1 AT E18552T1 AT 83401373 T AT83401373 T AT 83401373T AT 83401373 T AT83401373 T AT 83401373T AT E18552 T1 ATE18552 T1 AT E18552T1
Authority
AT
Austria
Prior art keywords
omegasulfone
imino
alpha
salts
amino
Prior art date
Application number
AT83401373T
Other languages
English (en)
Inventor
Jean Pierre Durlach
Original Assignee
Meram Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meram Lab filed Critical Meram Lab
Application granted granted Critical
Publication of ATE18552T1 publication Critical patent/ATE18552T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • C07D213/66—One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
AT83401373T 1982-07-05 1983-07-04 Salze von alpha-amino(und imino)-saeure, omegasulfon n-substituiert, kationische vektoren mit hoher cellularer penetration und herstellungsverfahren. ATE18552T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8211768A FR2529546A1 (fr) 1982-07-05 1982-07-05 Nouveaux sels d'amino-(et imino-)acides a, o-sulfoniques n-substitues, vecteurs cationiques de haute penetration cellulaire
EP83401373A EP0099799B1 (de) 1982-07-05 1983-07-04 Salze von alpha-Amino(und Imino)-Säure, omega-Sulfon N-substituiert, kationische Vektoren mit hoher cellularer Penetration und Herstellungsverfahren

Publications (1)

Publication Number Publication Date
ATE18552T1 true ATE18552T1 (de) 1986-03-15

Family

ID=9275686

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83401373T ATE18552T1 (de) 1982-07-05 1983-07-04 Salze von alpha-amino(und imino)-saeure, omegasulfon n-substituiert, kationische vektoren mit hoher cellularer penetration und herstellungsverfahren.

Country Status (8)

Country Link
US (1) US4563470A (de)
EP (1) EP0099799B1 (de)
JP (1) JPS6055067B2 (de)
AT (1) ATE18552T1 (de)
DE (1) DE3362536D1 (de)
ES (1) ES523839A0 (de)
FR (1) FR2529546A1 (de)
PT (1) PT76970B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60042896D1 (de) * 1999-04-28 2009-10-15 Bellus Health Int Ltd Zusammensetzungen und verfahren zur behandlung von amyloidosis mit sulphonatderivaten
US6562836B1 (en) 1999-05-24 2003-05-13 Queen's University Of Kingston Methods and compounds for inhibiting amyloid deposits
US20070010573A1 (en) * 2003-06-23 2007-01-11 Xianqi Kong Methods and compositions for treating amyloid-related diseases
US7414076B2 (en) * 2003-06-23 2008-08-19 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
US7244764B2 (en) * 2003-06-23 2007-07-17 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
US20060183800A1 (en) * 2004-11-12 2006-08-17 Xianqi Kong Methods and fluorinated compositions for treating amyloid-related diseases
US20060167057A1 (en) * 2004-11-16 2006-07-27 Xianqi Kong Compounds for the treatment of CNS and amyloid associated diseases
CA2592320C (en) * 2004-12-22 2015-11-24 Neurochem (International) Limited Methods and compositions for treating amyloid-related diseases
CA2666246C (en) * 2006-10-12 2013-12-31 Bellus Health (International) Limited Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid

Also Published As

Publication number Publication date
FR2529546A1 (fr) 1984-01-06
JPS5921666A (ja) 1984-02-03
EP0099799A1 (de) 1984-02-01
JPS6055067B2 (ja) 1985-12-03
PT76970B (fr) 1986-01-24
EP0099799B1 (de) 1986-03-12
ES8403873A1 (es) 1984-04-01
US4563470A (en) 1986-01-07
PT76970A (fr) 1983-07-01
ES523839A0 (es) 1984-04-01
DE3362536D1 (en) 1986-04-17
FR2529546B1 (de) 1985-02-08

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee