GB1490688A - Salts of 5-mercaptopyridoxine - Google Patents
Salts of 5-mercaptopyridoxineInfo
- Publication number
- GB1490688A GB1490688A GB18196/76A GB1819676A GB1490688A GB 1490688 A GB1490688 A GB 1490688A GB 18196/76 A GB18196/76 A GB 18196/76A GB 1819676 A GB1819676 A GB 1819676A GB 1490688 A GB1490688 A GB 1490688A
- Authority
- GB
- United Kingdom
- Prior art keywords
- mercaptopyridoxine
- disulphide
- acetal
- sulphide
- salts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- C07D213/66—One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal
- C07D213/67—2-Methyl-3-hydroxy-4,5-bis(hydroxy-methyl)pyridine, i.e. pyridoxine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
5-Mercaptopyridoxine alkanesulphonates of the general formula <IMAGE> in which X is 1 or 2, and the C1-4-alkane is straight-chain or branched, obtained by treating the corresponding sulphide or sulphide acetal or disulphide or disulphide acetal or the respective acid addition salts thereof with a C1-4-alkanesulphonic acid or an alkali metal or alkaline earth metal salt thereof. The compounds which can be prepared according to the invention can, for example, be used as very effective agents for the treatment of rheumatoid arthritis and similar inflammatory disorders.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57605575A | 1975-05-09 | 1975-05-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1490688A true GB1490688A (en) | 1977-11-02 |
Family
ID=24302783
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB18196/76A Expired GB1490688A (en) | 1975-05-09 | 1976-05-04 | Salts of 5-mercaptopyridoxine |
Country Status (29)
| Country | Link |
|---|---|
| JP (1) | JPS51138684A (en) |
| AR (1) | AR210883A1 (en) |
| AT (1) | AT348691B (en) |
| AU (1) | AU1342876A (en) |
| BE (1) | BE841593A (en) |
| BG (1) | BG25218A3 (en) |
| CA (1) | CA1088542A (en) |
| CH (1) | CH625222A5 (en) |
| CS (1) | CS189003B2 (en) |
| DD (1) | DD125482A5 (en) |
| DE (1) | DE2620325C3 (en) |
| DK (1) | DK143335C (en) |
| ES (1) | ES447717A1 (en) |
| FI (1) | FI61881C (en) |
| FR (1) | FR2310130A1 (en) |
| GB (1) | GB1490688A (en) |
| GR (1) | GR59817B (en) |
| HU (1) | HU172048B (en) |
| IE (1) | IE43030B1 (en) |
| IL (1) | IL49466A (en) |
| LU (1) | LU74892A1 (en) |
| NL (1) | NL7604285A (en) |
| NO (1) | NO144925C (en) |
| NZ (1) | NZ180691A (en) |
| PL (1) | PL100306B1 (en) |
| PT (1) | PT65061B (en) |
| RO (1) | RO68526A (en) |
| SE (1) | SE427033B (en) |
| ZA (1) | ZA762750B (en) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1695428C3 (en) * | 1967-06-08 | 1978-10-05 | Merck Patent Gmbh, 6100 Darmstadt | Derivatives of 5-mercaptopyridoxine and process for their preparation |
| US3852454A (en) * | 1973-06-15 | 1974-12-03 | Merck & Co Inc | Treatment of rheumatoid arthritis |
-
1976
- 1976-04-21 DK DK179376A patent/DK143335C/en not_active IP Right Cessation
- 1976-04-21 SE SE7604580A patent/SE427033B/en not_active IP Right Cessation
- 1976-04-21 FI FI761084A patent/FI61881C/en not_active IP Right Cessation
- 1976-04-22 NO NO761367A patent/NO144925C/en unknown
- 1976-04-22 NL NL7604285A patent/NL7604285A/en not_active Application Discontinuation
- 1976-04-24 RO RO7685792A patent/RO68526A/en unknown
- 1976-04-26 CH CH521976A patent/CH625222A5/en not_active IP Right Cessation
- 1976-04-26 NZ NZ180691A patent/NZ180691A/en unknown
- 1976-04-26 IL IL49466A patent/IL49466A/en unknown
- 1976-04-27 AR AR263046A patent/AR210883A1/en active
- 1976-04-28 AU AU13428/76A patent/AU1342876A/en not_active Expired
- 1976-04-29 GR GR50620A patent/GR59817B/en unknown
- 1976-04-30 PT PT65061A patent/PT65061B/en unknown
- 1976-05-04 GB GB18196/76A patent/GB1490688A/en not_active Expired
- 1976-05-04 CA CA251,741A patent/CA1088542A/en not_active Expired
- 1976-05-04 BG BG7600033100A patent/BG25218A3/en unknown
- 1976-05-05 FR FR7613351A patent/FR2310130A1/en active Granted
- 1976-05-06 PL PL1976189342A patent/PL100306B1/en unknown
- 1976-05-06 DD DD192709A patent/DD125482A5/xx unknown
- 1976-05-06 LU LU74892A patent/LU74892A1/xx unknown
- 1976-05-07 BE BE166849A patent/BE841593A/en unknown
- 1976-05-07 IE IE990/76A patent/IE43030B1/en unknown
- 1976-05-07 ES ES447717A patent/ES447717A1/en not_active Expired
- 1976-05-07 AT AT335676A patent/AT348691B/en not_active IP Right Cessation
- 1976-05-07 ZA ZA762750A patent/ZA762750B/en unknown
- 1976-05-07 DE DE2620325A patent/DE2620325C3/en not_active Expired
- 1976-05-07 CS CS763063A patent/CS189003B2/en unknown
- 1976-05-07 HU HU76ME00001974A patent/HU172048B/en unknown
- 1976-05-08 JP JP51051720A patent/JPS51138684A/en active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |
Effective date: 19920504 |