ES2000405A6 - Procedimiento para la preparacion de cotarnina - Google Patents
Procedimiento para la preparacion de cotarninaInfo
- Publication number
- ES2000405A6 ES2000405A6 ES8602195A ES8602195A ES2000405A6 ES 2000405 A6 ES2000405 A6 ES 2000405A6 ES 8602195 A ES8602195 A ES 8602195A ES 8602195 A ES8602195 A ES 8602195A ES 2000405 A6 ES2000405 A6 ES 2000405A6
- Authority
- ES
- Spain
- Prior art keywords
- cotarnine
- preparing
- salt
- represented
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- PAPMYQLKLNRZIR-UHFFFAOYSA-N Cotarnine Chemical compound C1CN(C)C(O)C2=C1C=C1OCOC1=C2OC PAPMYQLKLNRZIR-UHFFFAOYSA-N 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title 1
- -1 AMINO GROUP Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- IOEPOEDBBPRAEI-UHFFFAOYSA-N 1,2-dihydroisoquinoline Chemical compound C1=CC=C2CNC=CC2=C1 IOEPOEDBBPRAEI-UHFFFAOYSA-N 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- UWYZHKAOTLEWKK-UHFFFAOYSA-N tetrahydro-isoquinoline Natural products C1=CC=C2CNCCC2=C1 UWYZHKAOTLEWKK-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
SE DESCRIBE UN PROCEDIMIENTO DE PREPARACION DE COTARNINA QUE COMPRENDE OXIDAR EL GRUPO AMINO DE UN COMPUESTO DE TETRAHIDROISOQUINOLINA REPRESENTADO POR LA SIGUIENTE FORMULA (I): PARA CONVERTIR DICHO COMPUESTO EN UNA SAL DEL DIHIDROISOQUINOLINIO REPRESENTADO POR LA SIGUIENTE FORMULA (II): DONDE A- REPRESENTA UN ANION Y LUEGO HIDROLIZAR DICHA SAL DE DIHIDROISOQUINOLINIO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60201075A JPS6261982A (ja) | 1985-09-11 | 1985-09-11 | コタルニンの製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2000405A6 true ES2000405A6 (es) | 1988-02-16 |
Family
ID=16434974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES8602195A Expired ES2000405A6 (es) | 1985-09-11 | 1986-09-10 | Procedimiento para la preparacion de cotarnina |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4963684A (es) |
| EP (1) | EP0216696A3 (es) |
| JP (1) | JPS6261982A (es) |
| KR (1) | KR930010500B1 (es) |
| CA (1) | CA1294622C (es) |
| ES (1) | ES2000405A6 (es) |
| HU (1) | HU195659B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUT44774A (en) * | 1985-08-26 | 1988-04-28 | Mitsubishi Chem Ind | Process for producing benzylamine derivatives |
| US5362736A (en) * | 1991-02-27 | 1994-11-08 | Banyu Pharmaceutical Co., Ltd. | Isoquinoline derivatives |
| EP1300406B1 (en) * | 1997-07-11 | 2004-10-06 | Eisai Co., Ltd. | Method for producing pyridine compound |
| WO2005077936A1 (en) | 2004-02-11 | 2005-08-25 | Ulkar Kimya Sanayii Ve Ticaret A.S. | Pyridine benzimidazole sulfoxides with high purity |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUT44774A (en) * | 1985-08-26 | 1988-04-28 | Mitsubishi Chem Ind | Process for producing benzylamine derivatives |
| US4760145A (en) * | 1985-09-04 | 1988-07-26 | Mitsubishi Chemical Industries Limited | Certain 6,7-methylene dioxydihydro or tetrahydro-isoquinoline derivatives |
-
1985
- 1985-09-11 JP JP60201075A patent/JPS6261982A/ja active Pending
-
1986
- 1986-09-04 HU HU863811A patent/HU195659B/hu not_active IP Right Cessation
- 1986-09-10 ES ES8602195A patent/ES2000405A6/es not_active Expired
- 1986-09-10 CA CA000517921A patent/CA1294622C/en not_active Expired - Lifetime
- 1986-09-10 KR KR1019860007656A patent/KR930010500B1/ko not_active Expired - Lifetime
- 1986-09-11 EP EP86401991A patent/EP0216696A3/en not_active Withdrawn
-
1989
- 1989-02-07 US US07/307,247 patent/US4963684A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HUT41796A (en) | 1987-05-28 |
| HU195659B (en) | 1988-06-28 |
| CA1294622C (en) | 1992-01-21 |
| EP0216696A2 (en) | 1987-04-01 |
| JPS6261982A (ja) | 1987-03-18 |
| US4963684A (en) | 1990-10-16 |
| KR870003115A (ko) | 1987-04-15 |
| EP0216696A3 (en) | 1988-05-25 |
| KR930010500B1 (ko) | 1993-10-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES553714A0 (es) | Procedimiento para la preparacion de una composicion que contiene una sal de acido hialuronico. | |
| DK21889D0 (da) | Anvendelse af monacolin k, den tilsvarende carboxylsyreforbindelse eller salte af carboxylsyren til fremstilling af et laegemiddel til behandling af hypercholesterolaemi | |
| ES8706165A1 (es) | Un procedimiento para la preparacion de derivados de androstendiona 4-sustituida. | |
| MX168599B (es) | Procedimiento para la preparacion de compuestos cefemicos | |
| UA7088A1 (uk) | Спосіб одержання солі 2-(2-гідроксіетоксі)етіламіна та 3,6-діхлор-2-метоксібензойної кислоти | |
| GB1493998A (en) | Propanolamine derivatives | |
| ES540172A0 (es) | Procedimiento para produccion del compuesto (-)-trans-4-(4-fluorofenil)-3-(4-metoxifenoxi)metilpiperidina. | |
| ES8801903A1 (es) | Procedimiento para preparar derivados de cinolina | |
| ES2000405A6 (es) | Procedimiento para la preparacion de cotarnina | |
| EP0144991A3 (en) | Polymethosybenzyl piperazine derivatives, processes for their preparation and pharmaceutical compositions containing said derivatives | |
| ES2094812T3 (es) | Un procedimiento mejorado para la preparacion de derivados sustituidos de indolona. | |
| BR8703400A (pt) | Processo para a preparacao de um composto e de preparacao de um derivado intramolecular,composicao e processo para inibir a corrosao | |
| ES2012519A6 (es) | Procedimiento para preparar compuestos polifluorados. | |
| ES388885A1 (es) | Procedimiento para la preparacion de 1-(2-nitrilofenoxi)-2-hidroxi-3-etilaminopropano racemicos u opticamente activo. | |
| GR3001691T3 (en) | Novel crystalline salts of aryloxy-propanolamines, their preparation and their use | |
| GB1497161A (en) | Naphthyl derivatives | |
| GB8521516D0 (en) | Compounds | |
| ATE36700T1 (de) | Insbesondere fuer orale anwendung geeignete salze des carniting. | |
| GB1400851A (en) | Triidothyroalkyl compounds their method of preparation and therapeutical compositions containing such compounds | |
| ES2049243T3 (es) | Procedimiento para la preparacion y utilizacion de nuevos derivados de 2-tiozolidinona y composiciones farmaceuticas que los contienen. | |
| ES8600859A1 (es) | Procedimiento para preparar compuestos de pirimidina | |
| GB1503626A (en) | Substituted piperazine derivative its preparation and compositions containing it | |
| ES8504174A1 (es) | Un procedimiento para la preparacion de derivados de pirazolo-quinolinas. | |
| ES2034252T3 (es) | Procedimiento para la preparacion de compuestos macrolidos. | |
| ES2001662A6 (es) | Metodo para producir acidos 6b -halopenicilanicos asi como sales dse los mismos. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19981001 |