KR870003115A - 코타르닌의 제조방법 - Google Patents
코타르닌의 제조방법 Download PDFInfo
- Publication number
- KR870003115A KR870003115A KR1019860007656A KR860007656A KR870003115A KR 870003115 A KR870003115 A KR 870003115A KR 1019860007656 A KR1019860007656 A KR 1019860007656A KR 860007656 A KR860007656 A KR 860007656A KR 870003115 A KR870003115 A KR 870003115A
- Authority
- KR
- South Korea
- Prior art keywords
- halogenating agent
- salt
- general formula
- cotarin
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (5)
- 하기 일반식(Ⅰ)로 표시되는 테트라하이드로이소퀴놀린 화합물의 아미노기를 산화시켜 하기 일반식(Ⅱ)로 표시되는 디하이드로이소퀴놀리늄 염으로 전환시키고, 이어서 상기 디하이드로이소퀴놀리늄염을 가수분해시키는 단계를 포함하는 코타르닌의 제조방법 ;상기식에서, A는 음이온을 나타낸다.
- 제1항에 있어서, 할로겐화제를 사용하여 산화반응을 수행하는 방법.
- 제2항에 있어서, 할로겐화제가 Cl2, Br2및 I2로부터 선택되는 방법.
- 제2항에 있어서, 할로겐화제가 NaOCl, nAOBr, nAOI, Ca(ocL)2·nH2O, ClOH 및 BrOH부터 선택되는 하이포할로겐 산 또는 그들의 염인 방법.
- 제2항에 있어서, 할로겐화제 N-브로모숙신이미드 또는 N-클로로숙신이미드인 방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP201075 | 1985-09-11 | ||
| JP60201075A JPS6261982A (ja) | 1985-09-11 | 1985-09-11 | コタルニンの製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR870003115A true KR870003115A (ko) | 1987-04-15 |
| KR930010500B1 KR930010500B1 (ko) | 1993-10-25 |
Family
ID=16434974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019860007656A KR930010500B1 (ko) | 1985-09-11 | 1986-09-10 | 코타르닌의 제조방법 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4963684A (ko) |
| EP (1) | EP0216696A3 (ko) |
| JP (1) | JPS6261982A (ko) |
| KR (1) | KR930010500B1 (ko) |
| CA (1) | CA1294622C (ko) |
| ES (1) | ES2000405A6 (ko) |
| HU (1) | HU195659B (ko) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUT44774A (en) * | 1985-08-26 | 1988-04-28 | Mitsubishi Chem Ind | Process for producing benzylamine derivatives |
| US5362736A (en) * | 1991-02-27 | 1994-11-08 | Banyu Pharmaceutical Co., Ltd. | Isoquinoline derivatives |
| KR100559169B1 (ko) * | 1997-07-11 | 2006-03-10 | 에자이 가부시키가이샤 | 피리딘 유도체의 제조방법 |
| WO2005077936A1 (en) | 2004-02-11 | 2005-08-25 | Ulkar Kimya Sanayii Ve Ticaret A.S. | Pyridine benzimidazole sulfoxides with high purity |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUT44774A (en) * | 1985-08-26 | 1988-04-28 | Mitsubishi Chem Ind | Process for producing benzylamine derivatives |
| US4760145A (en) * | 1985-09-04 | 1988-07-26 | Mitsubishi Chemical Industries Limited | Certain 6,7-methylene dioxydihydro or tetrahydro-isoquinoline derivatives |
-
1985
- 1985-09-11 JP JP60201075A patent/JPS6261982A/ja active Pending
-
1986
- 1986-09-04 HU HU863811A patent/HU195659B/hu not_active IP Right Cessation
- 1986-09-10 ES ES8602195A patent/ES2000405A6/es not_active Expired
- 1986-09-10 KR KR1019860007656A patent/KR930010500B1/ko active IP Right Grant
- 1986-09-10 CA CA000517921A patent/CA1294622C/en not_active Expired - Fee Related
- 1986-09-11 EP EP86401991A patent/EP0216696A3/en not_active Withdrawn
-
1989
- 1989-02-07 US US07/307,247 patent/US4963684A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HU195659B (en) | 1988-06-28 |
| EP0216696A3 (en) | 1988-05-25 |
| ES2000405A6 (es) | 1988-02-16 |
| US4963684A (en) | 1990-10-16 |
| EP0216696A2 (en) | 1987-04-01 |
| JPS6261982A (ja) | 1987-03-18 |
| CA1294622C (en) | 1992-01-21 |
| HUT41796A (en) | 1987-05-28 |
| KR930010500B1 (ko) | 1993-10-25 |
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| G160 | Decision to publish patent application | ||
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| NORF | Unpaid initial registration fee |