ES8401768A1 - Procedimiento de obtener alcaloides bisindolicos. - Google Patents
Procedimiento de obtener alcaloides bisindolicos.Info
- Publication number
- ES8401768A1 ES8401768A1 ES517942A ES517942A ES8401768A1 ES 8401768 A1 ES8401768 A1 ES 8401768A1 ES 517942 A ES517942 A ES 517942A ES 517942 A ES517942 A ES 517942A ES 8401768 A1 ES8401768 A1 ES 8401768A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- hydrogen atom
- derivatives
- compounds
- vinblastinoyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001413 amino acids Chemical class 0.000 title abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000004185 ester group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- JXLYSJRDGCGARV-XQKSVPLYSA-N vincaleukoblastine Chemical class C([C@@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](OC(C)=O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(=O)OC)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1NC1=CC=CC=C21 JXLYSJRDGCGARV-XQKSVPLYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU83822A LU83822A1 (fr) | 1981-12-08 | 1981-12-08 | Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES517942A0 ES517942A0 (es) | 1984-01-01 |
| ES8401768A1 true ES8401768A1 (es) | 1984-01-01 |
Family
ID=19729780
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES517942A Expired ES8401768A1 (es) | 1981-12-08 | 1982-12-06 | Procedimiento de obtener alcaloides bisindolicos. |
Country Status (24)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE64396T1 (de) * | 1983-04-29 | 1991-06-15 | Omnichem Sa | Konjugierte vinblastin-verbindungen und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen. |
| US4675400A (en) * | 1985-06-17 | 1987-06-23 | Eli Lilly And Company | Bifunctional derivatives of 4-desacetyl indole-dihydroindole alkaloids |
| US4667030A (en) * | 1985-06-17 | 1987-05-19 | Eli Lilly And Company | Hydrazide succinimide derivatives of antineoplastic indole-dihydroindole alkaloids |
| CA1335686C (fr) * | 1986-01-13 | 1995-05-23 | Rao K. S. P. Bhushana | Vinblastine et composition pharmaceutique les contenant |
| US4906086A (en) * | 1987-06-19 | 1990-03-06 | Honda Giken Kogyo Kabushiki Kaisha | Rearview mirror device for motorcycles |
| FR2626882B1 (fr) * | 1988-02-08 | 1991-11-08 | Ire Celltarg Sa | Conjugues de derives de vinca comportant une chaine detergente en position c-3 |
| AU2014253584B2 (en) * | 2013-04-19 | 2017-02-02 | Jinan University | Vinca Alkaloid Derivatives, Preparation Method therefor and Application thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR204004A1 (es) | 1973-04-02 | 1975-11-12 | Lilly Co Eli | Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina |
| US3848234A (en) * | 1973-04-04 | 1974-11-12 | Sperry Rand Corp | Multi-processor system with multiple cache memories |
| IL48685A (en) * | 1975-01-09 | 1980-03-31 | Lilly Co Eli | Amides of vincadioline and vinblastine |
| OA06421A (fr) * | 1980-06-10 | 1981-09-30 | Omnium Chimique Sa | Procédé de préparation de dérivés N-(vinblastinoyl-23) d'acides aminés et de peptides. |
-
1981
- 1981-12-08 LU LU83822A patent/LU83822A1/fr unknown
-
1982
- 1982-11-24 AU AU90847/82A patent/AU564951B2/en not_active Ceased
- 1982-11-30 IL IL67366A patent/IL67366A/xx unknown
- 1982-12-01 CH CH6980/82A patent/CH655727A5/fr not_active IP Right Cessation
- 1982-12-01 ZA ZA828823A patent/ZA828823B/xx unknown
- 1982-12-03 NZ NZ202708A patent/NZ202708A/en unknown
- 1982-12-03 CA CA000416996A patent/CA1198422A/en not_active Expired
- 1982-12-06 GR GR69997A patent/GR77280B/el unknown
- 1982-12-06 ES ES517942A patent/ES8401768A1/es not_active Expired
- 1982-12-06 NL NL8204711A patent/NL8204711A/nl not_active Application Discontinuation
- 1982-12-07 IE IE2906/82A patent/IE55283B1/en not_active IP Right Cessation
- 1982-12-07 BE BE0/209661A patent/BE895262A/fr not_active IP Right Cessation
- 1982-12-07 DK DK541882A patent/DK161833C/da not_active IP Right Cessation
- 1982-12-07 FR FR828220476A patent/FR2517680B1/fr not_active Expired - Lifetime
- 1982-12-07 HU HU823919A patent/HU187803B/hu unknown
- 1982-12-07 PT PT75949A patent/PT75949B/pt not_active IP Right Cessation
- 1982-12-07 IT IT68431/82A patent/IT1157126B/it active
- 1982-12-07 SE SE8206981A patent/SE452622B/sv not_active IP Right Cessation
- 1982-12-07 DE DE19823245269 patent/DE3245269A1/de not_active Withdrawn
- 1982-12-07 AT AT0444982A patent/AT390958B/de not_active IP Right Cessation
- 1982-12-07 JP JP57214573A patent/JPS58116491A/ja active Granted
- 1982-12-08 DD DD82245703A patent/DD205906A5/de not_active IP Right Cessation
- 1982-12-08 GB GB08234965A patent/GB2111055B/en not_active Expired
- 1982-12-08 OA OA57864A patent/OA07270A/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20000601 |