ES8400099A1 - Procedimiento para la obtencion de diazolil-alcanoles. - Google Patents

Procedimiento para la obtencion de diazolil-alcanoles.

Info

Publication number
ES8400099A1
ES8400099A1 ES519038A ES519038A ES8400099A1 ES 8400099 A1 ES8400099 A1 ES 8400099A1 ES 519038 A ES519038 A ES 519038A ES 519038 A ES519038 A ES 519038A ES 8400099 A1 ES8400099 A1 ES 8400099A1
Authority
ES
Spain
Prior art keywords
carbon atoms
alkanoles
diazolyl
preparation
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES519038A
Other languages
English (en)
Other versions
ES519038A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES8400099A1 publication Critical patent/ES8400099A1/es
Publication of ES519038A0 publication Critical patent/ES519038A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/42—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing triple carbon-to-carbon bonds, e.g. with metal-alkynes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • C07C33/48—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts with unsaturation outside the aromatic rings
    • C07C33/483—Monocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Flanged Joints, Insulating Joints, And Other Joints (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Medicinal Preparation (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DIAZOLIL-ALCANOLES, DE FORMULA GENERAL (I), EN LA QUE A Y B SIGNIFICAN UN ATOMO DE NITROGENO O EL GRUPO CH; Y R SIGNIFICA ALQUENILO, ALQUINILO, FENILALQUENILO O FENILALQUINILO, Y SUS SALES DE ADICION DE ACIDO FISIOLOGICAMENTE ACEPTABLES.CONSISTE EN HACER REACCIONAR DIHALOGENOALCANOLES, DE FORMULA GENERAL (II), EN LA QUE R TIENE EL SIGNIFICADO YA MENCIONADO; Y HALK SIGNIFICA HALOGENO, CON AZOLES DE FORMULA (III), EN LA QUE A TIENE EL SIGNIFICADO YA INDICADO; Y M SIGNIFICA HIDROGENO O UN METAL ALCALINO, EN PRESENCIA DE UN DILUYENTE Y DE UNACEPTOR DE ACIDO.DE APLICACION EN MEDICINA POR SUS PROPIEDADES ANTIMICOTICAS.
ES519038A 1982-08-03 1983-01-17 Procedimiento para la obtencion de diazolil-alcanoles. Granted ES519038A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823228870 DE3228870A1 (de) 1982-08-03 1982-08-03 Diazolyl-alkanole, verfahren zu ihrer herstellung und ihre verwendung als antimykotische mittel

Publications (2)

Publication Number Publication Date
ES8400099A1 true ES8400099A1 (es) 1983-10-16
ES519038A0 ES519038A0 (es) 1983-10-16

Family

ID=6169963

Family Applications (1)

Application Number Title Priority Date Filing Date
ES519038A Granted ES519038A0 (es) 1982-08-03 1983-01-17 Procedimiento para la obtencion de diazolil-alcanoles.

Country Status (16)

Country Link
EP (1) EP0104300B1 (es)
JP (1) JPS5929671A (es)
KR (1) KR840004103A (es)
AT (1) ATE18763T1 (es)
AU (1) AU551411B2 (es)
CA (1) CA1198117A (es)
DE (2) DE3228870A1 (es)
DK (1) DK74683A (es)
ES (1) ES519038A0 (es)
FI (1) FI830152L (es)
GR (1) GR81379B (es)
HU (1) HU189632B (es)
IL (1) IL67980A (es)
NO (1) NO830655L (es)
PH (1) PH19658A (es)
ZA (1) ZA8346B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58738B1 (en) * 1984-09-05 1993-11-03 Ici Plc Antifungal azole compounds
US5194427A (en) * 1987-11-09 1993-03-16 Bayer Ag Antimycotic compositions of nikkomycin compounds and azole antimycotics
GB8819308D0 (en) * 1988-08-13 1988-09-14 Pfizer Ltd Triazole antifungal agents
GB9002375D0 (en) * 1990-02-02 1990-04-04 Pfizer Ltd Triazole antifungal agents
KR101220079B1 (ko) * 2011-04-22 2013-01-21 김현성 추간체 유합 케이지
MX2015014365A (es) * 2013-04-12 2015-12-07 Bayer Cropscience Ag Derivados de triazol novedosos.
US9668481B2 (en) * 2013-04-12 2017-06-06 Bayer Cropscience Aktiengesellschaft Triazole derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3991200A (en) * 1974-04-25 1976-11-09 American Cyanamid Company Substituted nitroimidazolyl thiadiazoles and oxadiazoles as antibacterial agents and growth promoting compounds
DE2820489A1 (de) * 1978-05-10 1979-11-15 Bayer Ag Hydroxypropyl-imidazole, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2928968A1 (de) * 1979-07-18 1981-02-12 Bayer Ag Antimikrobielle mittel
DE3018865A1 (de) * 1980-05-16 1981-11-26 Bayer Ag, 5090 Leverkusen Antimikrobielle mittel
ZA813354B (en) * 1980-06-02 1982-05-26 Ici Ltd Heterocyclic compounds

Also Published As

Publication number Publication date
JPS5929671A (ja) 1984-02-16
DK74683D0 (da) 1983-02-21
FI830152A0 (fi) 1983-01-17
AU1030483A (en) 1984-02-09
JPH0456035B2 (es) 1992-09-07
IL67980A (en) 1986-02-28
ZA8346B (en) 1983-10-26
PH19658A (en) 1986-06-09
KR840004103A (ko) 1984-10-06
DE3228870A1 (de) 1984-02-09
FI830152L (fi) 1984-02-04
EP0104300A1 (de) 1984-04-04
CA1198117A (en) 1985-12-17
GR81379B (es) 1984-12-11
DE3362634D1 (en) 1986-04-30
IL67980A0 (en) 1983-06-15
EP0104300B1 (de) 1986-03-26
AU551411B2 (en) 1986-05-01
ES519038A0 (es) 1983-10-16
ATE18763T1 (de) 1986-04-15
DK74683A (da) 1984-02-04
NO830655L (no) 1984-02-06
HU189632B (en) 1986-07-28

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