AU551411B2 - Diazolylalkanols useful as antimycotic agents - Google Patents

Diazolylalkanols useful as antimycotic agents

Info

Publication number
AU551411B2
AU551411B2 AU10304/83A AU1030483A AU551411B2 AU 551411 B2 AU551411 B2 AU 551411B2 AU 10304/83 A AU10304/83 A AU 10304/83A AU 1030483 A AU1030483 A AU 1030483A AU 551411 B2 AU551411 B2 AU 551411B2
Authority
AU
Australia
Prior art keywords
carbon atoms
diazolylalkanols
useful
halogen
alkynyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU10304/83A
Other versions
AU1030483A (en
Inventor
Karl Heinz Buchel
Manfred Plempel
Erik Regel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of AU1030483A publication Critical patent/AU1030483A/en
Application granted granted Critical
Publication of AU551411B2 publication Critical patent/AU551411B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/42—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing triple carbon-to-carbon bonds, e.g. with metal-alkynes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • C07C33/48—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts with unsaturation outside the aromatic rings
    • C07C33/483—Monocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Medicinal Preparation (AREA)
  • Flanged Joints, Insulating Joints, And Other Joints (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

1. Diazolylalkanols of the general formula I see diagramm : EP0104300,P9,F1 in which R represents alkenyl and alkynyl, each having 2 to 6 carbon atoms, and represents phenylalkenyl, having 2 to 4 carbon atoms in the alkenyl part, or phenylalkynyl, having 2 to 4 carbon atoms in the alkynyl part, each optionally identically or differently substituted once to three times, the phenyl substituents which may be mentioned in each case being : halogen, alkyl having 1 to 4 carbon atoms, alkoxy and alkylthio each having 1 to 2 carbon atoms, alkoxyalkyl having 1 to 2 carbon atoms in each alkyl part and phenyl which is optinally substituted by halogen and physiologically tolerated acid addition salts thereof.
AU10304/83A 1982-08-03 1983-01-12 Diazolylalkanols useful as antimycotic agents Ceased AU551411B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE32288700 1982-08-03
DE19823228870 DE3228870A1 (en) 1982-08-03 1982-08-03 DIAZOLYL-ALKANOLE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS AN ANTIMYCOTIC AGENT

Publications (2)

Publication Number Publication Date
AU1030483A AU1030483A (en) 1984-02-09
AU551411B2 true AU551411B2 (en) 1986-05-01

Family

ID=6169963

Family Applications (1)

Application Number Title Priority Date Filing Date
AU10304/83A Ceased AU551411B2 (en) 1982-08-03 1983-01-12 Diazolylalkanols useful as antimycotic agents

Country Status (16)

Country Link
EP (1) EP0104300B1 (en)
JP (1) JPS5929671A (en)
KR (1) KR840004103A (en)
AT (1) ATE18763T1 (en)
AU (1) AU551411B2 (en)
CA (1) CA1198117A (en)
DE (2) DE3228870A1 (en)
DK (1) DK74683A (en)
ES (1) ES8400099A1 (en)
FI (1) FI830152L (en)
GR (1) GR81379B (en)
HU (1) HU189632B (en)
IL (1) IL67980A (en)
NO (1) NO830655L (en)
PH (1) PH19658A (en)
ZA (1) ZA8346B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5194427A (en) * 1987-11-09 1993-03-16 Bayer Ag Antimycotic compositions of nikkomycin compounds and azole antimycotics

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58738B1 (en) * 1984-09-05 1993-11-03 Ici Plc Antifungal azole compounds
GB8819308D0 (en) * 1988-08-13 1988-09-14 Pfizer Ltd Triazole antifungal agents
GB9002375D0 (en) * 1990-02-02 1990-04-04 Pfizer Ltd Triazole antifungal agents
KR101220079B1 (en) * 2011-04-22 2013-01-21 김현성 Lumbar Interbody Fusion Cage
MX2015014365A (en) * 2013-04-12 2015-12-07 Bayer Cropscience Ag Novel triazole derivatives.
KR20150140381A (en) * 2013-04-12 2015-12-15 바이엘 크롭사이언스 악티엔게젤샤프트 Novel triazole derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3991200A (en) * 1974-04-25 1976-11-09 American Cyanamid Company Substituted nitroimidazolyl thiadiazoles and oxadiazoles as antibacterial agents and growth promoting compounds
DE2820489A1 (en) * 1978-05-10 1979-11-15 Bayer Ag 2,3-Di:aryl-2-hydroxy:propyl-imidazole derivs. - useful as antimycotic agents
DE2928968A1 (en) * 1979-07-18 1981-02-12 Bayer Ag ANTIMICROBIAL AGENTS
DE3018865A1 (en) * 1980-05-16 1981-11-26 Bayer Ag, 5090 Leverkusen ANTIMICROBIAL AGENTS
ZA813354B (en) * 1980-06-02 1982-05-26 Ici Ltd Heterocyclic compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5194427A (en) * 1987-11-09 1993-03-16 Bayer Ag Antimycotic compositions of nikkomycin compounds and azole antimycotics

Also Published As

Publication number Publication date
AU1030483A (en) 1984-02-09
CA1198117A (en) 1985-12-17
NO830655L (en) 1984-02-06
FI830152L (en) 1984-02-04
ES519038A0 (en) 1983-10-16
ES8400099A1 (en) 1983-10-16
DE3228870A1 (en) 1984-02-09
ZA8346B (en) 1983-10-26
HU189632B (en) 1986-07-28
DK74683A (en) 1984-02-04
DE3362634D1 (en) 1986-04-30
JPH0456035B2 (en) 1992-09-07
EP0104300A1 (en) 1984-04-04
JPS5929671A (en) 1984-02-16
FI830152A0 (en) 1983-01-17
GR81379B (en) 1984-12-11
DK74683D0 (en) 1983-02-21
ATE18763T1 (en) 1986-04-15
EP0104300B1 (en) 1986-03-26
PH19658A (en) 1986-06-09
KR840004103A (en) 1984-10-06
IL67980A (en) 1986-02-28
IL67980A0 (en) 1983-06-15

Similar Documents

Publication Publication Date Title
BR8901097A (en) PROCESS FOR THE PREPARATION OF A BIOCIDAL COMPOSITION
AU551411B2 (en) Diazolylalkanols useful as antimycotic agents
DE3465085D1 (en) Derivatives of 4-(3-alkynyloxy-2-hydroxy-propyl)-piperazin-1-yl-n-phenyl acetamide, their preparation and their therapeutical use
IL58321A (en) N-oxadiazolyl(thiadiazolyl)alkyl-halogenoacetanilides,their preparation and their use as herbicides
AU571314B2 (en) Monosilylated aminophenylethylamine derivatives
IL71522A0 (en) N-sulphenylated phenethylsulphonamides,their preparation and their use as pesticides
DE3561818D1 (en) Isoxazoloquinolinone derivatives, process and intermediates for their preparation, use as medicaments and compositions containing them
PT80490B (en) O-3-PHENYL-6-CHLOROPYRIDAZINYL- (4) -7-S- (N-OCTILE) -TEOCARBONATE, 2-CHLORO-4-ETHYLAMINO-6-ISOPROPYLAMINO- 1,3,5-TRIAZINE AND A CHLOROACETAMIDE