ZA8346B - Diazolylalkanols,process for their prepartion and their use as antimycotic agents - Google Patents

Diazolylalkanols,process for their prepartion and their use as antimycotic agents

Info

Publication number
ZA8346B
ZA8346B ZA8346A ZA8346A ZA8346B ZA 8346 B ZA8346 B ZA 8346B ZA 8346 A ZA8346 A ZA 8346A ZA 8346 A ZA8346 A ZA 8346A ZA 8346 B ZA8346 B ZA 8346B
Authority
ZA
South Africa
Prior art keywords
carbon atoms
diazolylalkanols
prepartion
halogen
alkynyl
Prior art date
Application number
ZA8346A
Inventor
Erik Regel
Karl Heinz Buechel
Manfred Plempel
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA8346B publication Critical patent/ZA8346B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/42—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing triple carbon-to-carbon bonds, e.g. with metal-alkynes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • C07C33/48—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts with unsaturation outside the aromatic rings
    • C07C33/483—Monocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Flanged Joints, Insulating Joints, And Other Joints (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Catalysts (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

1. Diazolylalkanols of the general formula I see diagramm : EP0104300,P9,F1 in which R represents alkenyl and alkynyl, each having 2 to 6 carbon atoms, and represents phenylalkenyl, having 2 to 4 carbon atoms in the alkenyl part, or phenylalkynyl, having 2 to 4 carbon atoms in the alkynyl part, each optionally identically or differently substituted once to three times, the phenyl substituents which may be mentioned in each case being : halogen, alkyl having 1 to 4 carbon atoms, alkoxy and alkylthio each having 1 to 2 carbon atoms, alkoxyalkyl having 1 to 2 carbon atoms in each alkyl part and phenyl which is optinally substituted by halogen and physiologically tolerated acid addition salts thereof.
ZA8346A 1982-08-03 1983-01-05 Diazolylalkanols,process for their prepartion and their use as antimycotic agents ZA8346B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823228870 DE3228870A1 (en) 1982-08-03 1982-08-03 DIAZOLYL-ALKANOLE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS AN ANTIMYCOTIC AGENT

Publications (1)

Publication Number Publication Date
ZA8346B true ZA8346B (en) 1983-10-26

Family

ID=6169963

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA8346A ZA8346B (en) 1982-08-03 1983-01-05 Diazolylalkanols,process for their prepartion and their use as antimycotic agents

Country Status (16)

Country Link
EP (1) EP0104300B1 (en)
JP (1) JPS5929671A (en)
KR (1) KR840004103A (en)
AT (1) ATE18763T1 (en)
AU (1) AU551411B2 (en)
CA (1) CA1198117A (en)
DE (2) DE3228870A1 (en)
DK (1) DK74683A (en)
ES (1) ES519038A0 (en)
FI (1) FI830152L (en)
GR (1) GR81379B (en)
HU (1) HU189632B (en)
IL (1) IL67980A (en)
NO (1) NO830655L (en)
PH (1) PH19658A (en)
ZA (1) ZA8346B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58738B1 (en) * 1984-09-05 1993-11-03 Ici Plc Antifungal azole compounds
US5194427A (en) * 1987-11-09 1993-03-16 Bayer Ag Antimycotic compositions of nikkomycin compounds and azole antimycotics
GB8819308D0 (en) * 1988-08-13 1988-09-14 Pfizer Ltd Triazole antifungal agents
GB9002375D0 (en) * 1990-02-02 1990-04-04 Pfizer Ltd Triazole antifungal agents
KR101220079B1 (en) * 2011-04-22 2013-01-21 김현성 Lumbar Interbody Fusion Cage
CN105283450B (en) * 2013-04-12 2018-12-18 拜耳作物科学股份公司 Triazole derivative
JP6397482B2 (en) * 2013-04-12 2018-09-26 バイエル・クロップサイエンス・アクチェンゲゼルシャフト New triazole derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3991200A (en) * 1974-04-25 1976-11-09 American Cyanamid Company Substituted nitroimidazolyl thiadiazoles and oxadiazoles as antibacterial agents and growth promoting compounds
DE2820489A1 (en) * 1978-05-10 1979-11-15 Bayer Ag 2,3-Di:aryl-2-hydroxy:propyl-imidazole derivs. - useful as antimycotic agents
DE2928968A1 (en) * 1979-07-18 1981-02-12 Bayer Ag ANTIMICROBIAL AGENTS
DE3018865A1 (en) * 1980-05-16 1981-11-26 Bayer Ag, 5090 Leverkusen ANTIMICROBIAL AGENTS
ZA813354B (en) * 1980-06-02 1982-05-26 Ici Ltd Heterocyclic compounds

Also Published As

Publication number Publication date
PH19658A (en) 1986-06-09
ES8400099A1 (en) 1983-10-16
ES519038A0 (en) 1983-10-16
EP0104300B1 (en) 1986-03-26
DK74683D0 (en) 1983-02-21
IL67980A0 (en) 1983-06-15
DE3228870A1 (en) 1984-02-09
KR840004103A (en) 1984-10-06
FI830152A0 (en) 1983-01-17
JPS5929671A (en) 1984-02-16
AU1030483A (en) 1984-02-09
DK74683A (en) 1984-02-04
GR81379B (en) 1984-12-11
JPH0456035B2 (en) 1992-09-07
ATE18763T1 (en) 1986-04-15
IL67980A (en) 1986-02-28
EP0104300A1 (en) 1984-04-04
FI830152L (en) 1984-02-04
NO830655L (en) 1984-02-06
HU189632B (en) 1986-07-28
DE3362634D1 (en) 1986-04-30
AU551411B2 (en) 1986-05-01
CA1198117A (en) 1985-12-17

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