ES8305362A1 - Un procedimiento para preparar derivados de antibioticos-lactamicos. - Google Patents
Un procedimiento para preparar derivados de antibioticos-lactamicos.Info
- Publication number
- ES8305362A1 ES8305362A1 ES509837A ES509837A ES8305362A1 ES 8305362 A1 ES8305362 A1 ES 8305362A1 ES 509837 A ES509837 A ES 509837A ES 509837 A ES509837 A ES 509837A ES 8305362 A1 ES8305362 A1 ES 8305362A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- translation
- procedure
- machine
- legally binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 150000007522 mineralic acids Chemical class 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 239000011701 zinc Substances 0.000 abstract 1
- 229910052725 zinc Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Abstract
UN PROCEDIMIENTO PARA PREPARAR DERIVADOS DE ANTIBIOTICOS B-BACTAMICOS. CONSTA DE LAS SIGUIENTES ETAPAS: 1 ) SOMETER A REACCION A UN COMPUESTO (II) CON R Y EN UN DISOLVENTE HIDROCARBONADO ALIFATICO HALOGENADO. 2 ) HACER REACCIONAR EL COMPUESTO OBTENIDO CON ZINC Y UN ACIDO SELECCIONADO DE ENTRE ACIDOS INORGANICOS, MONOESTERES DE ACIDOS INORGANICOS DIBASICOS Y ACIDOS SULFONICOS, EN UN DISOLVENTE INERTE. 3 ) SI ES NECESARIO SE SOLIFICA EL COMPUESTO OBTENIDO (I) PARA DAR LA SAL CORRESPONDIENTE FARMACEUTICAMENTE ACEPTABLE. R ES UN GRUPO ACILO; R ES UN ATOMO DE HIDROGENO O UN GRUPO METOXI; R ES UN GRUPO AMINODINOTIO O UN GRUPO HETEROCICLILTIO; X ES AZUFRE, OXIGENO O UN GRUPO METILENO.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56025059A JPS57139077A (en) | 1981-02-23 | 1981-02-23 | Eliminating method of protecting group from carboxy group |
| JP4485481A JPS57159789A (en) | 1981-03-27 | 1981-03-27 | Preparation of cephamycin derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8305362A1 true ES8305362A1 (es) | 1983-04-01 |
| ES509837A0 ES509837A0 (es) | 1983-04-01 |
Family
ID=26362653
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES509837A Granted ES509837A0 (es) | 1981-02-23 | 1982-02-23 | Un procedimiento para preparar derivados de antibioticos-lactamicos. |
Country Status (8)
| Country | Link |
|---|---|
| CA (1) | CA1194470A (es) |
| CH (1) | CH646977A5 (es) |
| DK (1) | DK162603C (es) |
| ES (1) | ES509837A0 (es) |
| FI (1) | FI72521C (es) |
| IT (1) | IT1157951B (es) |
| NL (1) | NL8200708A (es) |
| SE (1) | SE452620B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101302226B (zh) * | 2008-06-12 | 2011-01-12 | 齐鲁安替制药有限公司 | 头霉素中间体化合物的制备方法 |
| CN113512046B (zh) * | 2021-03-31 | 2023-04-25 | 西南大学 | C-7位卤代酰基头孢化合物、制备方法和应用 |
-
1982
- 1982-02-22 CH CH108282A patent/CH646977A5/de not_active IP Right Cessation
- 1982-02-22 DK DK075582A patent/DK162603C/da not_active IP Right Cessation
- 1982-02-22 SE SE8201087A patent/SE452620B/sv unknown
- 1982-02-23 CA CA000396796A patent/CA1194470A/en not_active Expired
- 1982-02-23 IT IT67194/82A patent/IT1157951B/it active
- 1982-02-23 ES ES509837A patent/ES509837A0/es active Granted
- 1982-02-23 FI FI820582A patent/FI72521C/fi not_active IP Right Cessation
- 1982-02-23 NL NL8200708A patent/NL8200708A/nl not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NL8200708A (nl) | 1982-09-16 |
| CH646977A5 (en) | 1984-12-28 |
| IT8267194A0 (it) | 1982-02-23 |
| DK75582A (da) | 1982-08-24 |
| FI72521C (fi) | 1987-06-08 |
| DK162603B (da) | 1991-11-18 |
| SE8201087L (sv) | 1982-08-24 |
| DK162603C (da) | 1992-04-06 |
| SE452620B (sv) | 1987-12-07 |
| ES509837A0 (es) | 1983-04-01 |
| FI72521B (fi) | 1987-02-27 |
| CA1194470A (en) | 1985-10-01 |
| IT1157951B (it) | 1987-02-18 |
| FI820582L (fi) | 1982-08-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19990405 |