JPS5531041A - Reserpilinic acid derivative - Google Patents

Reserpilinic acid derivative

Info

Publication number
JPS5531041A
JPS5531041A JP10417978A JP10417978A JPS5531041A JP S5531041 A JPS5531041 A JP S5531041A JP 10417978 A JP10417978 A JP 10417978A JP 10417978 A JP10417978 A JP 10417978A JP S5531041 A JPS5531041 A JP S5531041A
Authority
JP
Japan
Prior art keywords
reserpilinic
acid
pref
mole
acid derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10417978A
Other languages
Japanese (ja)
Other versions
JPS6365674B2 (en
Inventor
Hideo Fukushima
Masao Nagase
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nisshin Seifun Group Inc
Original Assignee
Nisshin Seifun Group Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nisshin Seifun Group Inc filed Critical Nisshin Seifun Group Inc
Priority to JP10417978A priority Critical patent/JPS5531041A/en
Publication of JPS5531041A publication Critical patent/JPS5531041A/en
Publication of JPS6365674B2 publication Critical patent/JPS6365674B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A reserpilinic acid derivative of formula (R is halobenzyl or alkylbenzyl).
EXAMPLE: Reserpilinic acid p-chlorobenzyl ester.
USE: Anti-arrhythmic agent.
PROCESS: The compound of the formula is prepared by esterifying reserpilinic acid with a subtituted benzyl halide (pref. ≥1 mole per 1 mole of reserpilinic acid), in an organic solvent such as isopropanol, etc., in the presence of an alkali metal carbonate such as sodium carbonate, lithium carbonate, etc.(pref. ≥1 mole per 1 mole of the substituted benzyl halide), pref. in the presence of an inert gas, at 50W120°C.
COPYRIGHT: (C)1980,JPO&Japio
JP10417978A 1978-08-26 1978-08-26 Reserpilinic acid derivative Granted JPS5531041A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10417978A JPS5531041A (en) 1978-08-26 1978-08-26 Reserpilinic acid derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10417978A JPS5531041A (en) 1978-08-26 1978-08-26 Reserpilinic acid derivative

Publications (2)

Publication Number Publication Date
JPS5531041A true JPS5531041A (en) 1980-03-05
JPS6365674B2 JPS6365674B2 (en) 1988-12-16

Family

ID=14373776

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10417978A Granted JPS5531041A (en) 1978-08-26 1978-08-26 Reserpilinic acid derivative

Country Status (1)

Country Link
JP (1) JPS5531041A (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5113799A (en) * 1974-07-22 1976-02-03 Nisshin Flour Milling Co RESERUPIRIN JUDOTAINO SEIZOHO

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5113799A (en) * 1974-07-22 1976-02-03 Nisshin Flour Milling Co RESERUPIRIN JUDOTAINO SEIZOHO

Also Published As

Publication number Publication date
JPS6365674B2 (en) 1988-12-16

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