JPS6479158A - 2-nitroimidazole derivative - Google Patents

2-nitroimidazole derivative

Info

Publication number
JPS6479158A
JPS6479158A JP23700587A JP23700587A JPS6479158A JP S6479158 A JPS6479158 A JP S6479158A JP 23700587 A JP23700587 A JP 23700587A JP 23700587 A JP23700587 A JP 23700587A JP S6479158 A JPS6479158 A JP S6479158A
Authority
JP
Japan
Prior art keywords
nitroimidazole
derivative
hydroxylamine
formula
methyl ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP23700587A
Other languages
Japanese (ja)
Other versions
JP2598649B2 (en
Inventor
Seiichi Inayama
Hitoshi Hori
Tomoyuki Mori
Yasuto Onoyama
Mitsusachi Abe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taiho Pharmaceutical Co Ltd
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Priority to JP23700587A priority Critical patent/JP2598649B2/en
Publication of JPS6479158A publication Critical patent/JPS6479158A/en
Application granted granted Critical
Publication of JP2598649B2 publication Critical patent/JP2598649B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:The 2-nitroimidazole derivative of formula (R is H or acetyl) and its salt. EXAMPLE:2-Nitroimidazole-1-acetohydroxamic acid. USE:Useful as a radiation sensitizer. It has low toxicity. PREPARATION:The compound of formula can be produced e.g. by reacting 2-nitroimidazole-1-acetic acid methyl ester with hydroxylamine or its derivative in a solvent (e.g., methanol) at 10-25 deg.C for 1-24hr. The amount of hydroxylamine, etc., is preferably 4-5mol. per 1mol. of the methyl ester.
JP23700587A 1987-09-21 1987-09-21 2-nitroimidazole derivative Expired - Lifetime JP2598649B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP23700587A JP2598649B2 (en) 1987-09-21 1987-09-21 2-nitroimidazole derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP23700587A JP2598649B2 (en) 1987-09-21 1987-09-21 2-nitroimidazole derivative

Publications (2)

Publication Number Publication Date
JPS6479158A true JPS6479158A (en) 1989-03-24
JP2598649B2 JP2598649B2 (en) 1997-04-09

Family

ID=17008974

Family Applications (1)

Application Number Title Priority Date Filing Date
JP23700587A Expired - Lifetime JP2598649B2 (en) 1987-09-21 1987-09-21 2-nitroimidazole derivative

Country Status (1)

Country Link
JP (1) JP2598649B2 (en)

Also Published As

Publication number Publication date
JP2598649B2 (en) 1997-04-09

Similar Documents

Publication Publication Date Title
IE791565L (en) Crop cutting apparatus
IE792112L (en) Process for the manufacture of 1,2,3-thiadiazol-5-yl ureas
JPS57179147A (en) Amidine derivative
ES8304971A1 (en) Process for the preparation of azabicyclo(3.2.0)-hept-2-ene derivatives.
JPS6479158A (en) 2-nitroimidazole derivative
JPS54112864A (en) Novel imidazole derivative, its mineral acid salt, and their preparation
JPS55111483A (en) Novel phenothiazine derivative and psychotropic drug comprising it
ES476565A1 (en) Fungicidal phenypyrol derivatives
ES8206522A1 (en) Process for the Preparation of Apovincaminic Acid Esters
JPS5538301A (en) New derivative of antibiotics fortimicin and its preparation
ES483699A1 (en) New process for preparing an 1H-indazol-3-ylacetic acid derivative.
JPS5721321A (en) Antihyperlipemic agent
JPS5551079A (en) Preparation of benzoxazole derivative
JPS55122797A (en) Novel nitrosourea derivative and its preparation
JPS5687590A (en) Diphosphoglycerine derivative
JPS6479138A (en) 1-biphenylylethanol derivative and production thereof
JPS55102548A (en) Nitrosamine derivative
JPS55120591A (en) Phosphinoethylmalonic acid derivative, and preparation thereof
JPS5738773A (en) Pyrazoline compound and its preparation
ES479300A1 (en) An alpha-methyl-4(2'-thienyl-carbonyl)phenyl acetic acid derivative, process for its preparation and its pharmaceutical use.
JPS55115898A (en) 3",4"-diacyltylosin derivative
JPS6456667A (en) Nitric acid ester derivative
JPS57185284A (en) 7-deazapurine derivative and its preparation
TH5420EX (en) Thionophosphonic acid ester
JPS5629542A (en) Preparation of phenylacetic acid derivative