JPS57185284A - 7-deazapurine derivative and its preparation - Google Patents

7-deazapurine derivative and its preparation

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Publication number
JPS57185284A
JPS57185284A JP6863981A JP6863981A JPS57185284A JP S57185284 A JPS57185284 A JP S57185284A JP 6863981 A JP6863981 A JP 6863981A JP 6863981 A JP6863981 A JP 6863981A JP S57185284 A JPS57185284 A JP S57185284A
Authority
JP
Japan
Prior art keywords
compound shown
base
benzyl
formulai
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6863981A
Other languages
Japanese (ja)
Inventor
Toshio Goto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Priority to JP6863981A priority Critical patent/JPS57185284A/en
Publication of JPS57185284A publication Critical patent/JPS57185284A/en
Pending legal-status Critical Current

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  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

NEW MATERIAL:A compound shown by the formulaI(R1 is lower alkyl; R2 is benzyl or lower alkoxy-substituted benzyl).
EXAMPLE: 2-Amino-7-benzyl-3-isopropyloxymethylpyrrolo( 2, 3,-d )pyrimidine-4-one- 5-carbaldehyde.
USE: An intermediate for synthesizing a Q base and its analogues. The Q base is a substance existing in a specific tRNA, and useful as a drug such as a carcinostatic agent or a biological reagent. The use of the compound shown by the formulaIcan produce the Q base industrially in high yield.
PROCESS: A compound shown by the formula II is oxidized with an oxidizing agent such as manganese dioxide, chromic acid, etc., to give a compound shown by the formulaI. The reaction is carried out in a solvent such as ethyl acetate, etc. at -20°CW the reflux temperature of the reaction system.
COPYRIGHT: (C)1982,JPO&Japio
JP6863981A 1981-05-06 1981-05-06 7-deazapurine derivative and its preparation Pending JPS57185284A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP6863981A JPS57185284A (en) 1981-05-06 1981-05-06 7-deazapurine derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6863981A JPS57185284A (en) 1981-05-06 1981-05-06 7-deazapurine derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS57185284A true JPS57185284A (en) 1982-11-15

Family

ID=13379496

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6863981A Pending JPS57185284A (en) 1981-05-06 1981-05-06 7-deazapurine derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS57185284A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4571423A (en) * 1982-03-16 1986-02-18 Takeda Chemical Industries Ltd. Substituted 5-aminomethyl-2-acylaminopyrrolo[2,3-d]pyrimidin-4-ones

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4571423A (en) * 1982-03-16 1986-02-18 Takeda Chemical Industries Ltd. Substituted 5-aminomethyl-2-acylaminopyrrolo[2,3-d]pyrimidin-4-ones

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