JPS57185284A - 7-deazapurine derivative and its preparation - Google Patents
7-deazapurine derivative and its preparationInfo
- Publication number
- JPS57185284A JPS57185284A JP6863981A JP6863981A JPS57185284A JP S57185284 A JPS57185284 A JP S57185284A JP 6863981 A JP6863981 A JP 6863981A JP 6863981 A JP6863981 A JP 6863981A JP S57185284 A JPS57185284 A JP S57185284A
- Authority
- JP
- Japan
- Prior art keywords
- compound shown
- base
- benzyl
- formulai
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
NEW MATERIAL:A compound shown by the formulaI(R1 is lower alkyl; R2 is benzyl or lower alkoxy-substituted benzyl).
EXAMPLE: 2-Amino-7-benzyl-3-isopropyloxymethylpyrrolo( 2, 3,-d )pyrimidine-4-one- 5-carbaldehyde.
USE: An intermediate for synthesizing a Q base and its analogues. The Q base is a substance existing in a specific tRNA, and useful as a drug such as a carcinostatic agent or a biological reagent. The use of the compound shown by the formulaIcan produce the Q base industrially in high yield.
PROCESS: A compound shown by the formula II is oxidized with an oxidizing agent such as manganese dioxide, chromic acid, etc., to give a compound shown by the formulaI. The reaction is carried out in a solvent such as ethyl acetate, etc. at -20°CW the reflux temperature of the reaction system.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6863981A JPS57185284A (en) | 1981-05-06 | 1981-05-06 | 7-deazapurine derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6863981A JPS57185284A (en) | 1981-05-06 | 1981-05-06 | 7-deazapurine derivative and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57185284A true JPS57185284A (en) | 1982-11-15 |
Family
ID=13379496
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6863981A Pending JPS57185284A (en) | 1981-05-06 | 1981-05-06 | 7-deazapurine derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57185284A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4571423A (en) * | 1982-03-16 | 1986-02-18 | Takeda Chemical Industries Ltd. | Substituted 5-aminomethyl-2-acylaminopyrrolo[2,3-d]pyrimidin-4-ones |
-
1981
- 1981-05-06 JP JP6863981A patent/JPS57185284A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4571423A (en) * | 1982-03-16 | 1986-02-18 | Takeda Chemical Industries Ltd. | Substituted 5-aminomethyl-2-acylaminopyrrolo[2,3-d]pyrimidin-4-ones |
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