ES8302680A1 - "un procedimiento para sintetizar 3(4-fenil-1-piperacinio-1-il)-1,2-propandiol 3(teofilin-7-il)-1-propansulfonato" - Google Patents
"un procedimiento para sintetizar 3(4-fenil-1-piperacinio-1-il)-1,2-propandiol 3(teofilin-7-il)-1-propansulfonato"Info
- Publication number
- ES8302680A1 ES8302680A1 ES509850A ES509850A ES8302680A1 ES 8302680 A1 ES8302680 A1 ES 8302680A1 ES 509850 A ES509850 A ES 509850A ES 509850 A ES509850 A ES 509850A ES 8302680 A1 ES8302680 A1 ES 8302680A1
- Authority
- ES
- Spain
- Prior art keywords
- compound
- antitussive activity
- theophyllin
- propanediol
- antitussive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8109343A IT1210639B (it) | 1981-02-25 | 1981-02-25 | Prodotto: 3(4-fenil1piperazinio-1-il)-1,2-propandiolo 3(teofillin-7-il)-1propansolfonato,utilizzabile in terapia,e relativo procedimento di fabbricazione |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES509850A0 ES509850A0 (es) | 1983-02-01 |
| ES8302680A1 true ES8302680A1 (es) | 1983-02-01 |
Family
ID=11128724
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES509850A Expired ES8302680A1 (es) | 1981-02-25 | 1982-02-24 | "un procedimiento para sintetizar 3(4-fenil-1-piperacinio-1-il)-1,2-propandiol 3(teofilin-7-il)-1-propansulfonato" |
Country Status (18)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1203721B (it) * | 1983-12-29 | 1989-02-23 | Dompe Farmaceutici Spa | Composti otticamente attivi ad attivita' antitosse e sedativa centrale,procedimento per la preparazione e composizioni che li contengono |
| IT1217950B (it) * | 1988-06-28 | 1990-03-30 | Dott Formenti Ind Chimica E Fa | Sali di (r,s) 3 (4 fenil 1 piperazinil) 1,2 propandtolo |
| IT1231158B (it) * | 1989-07-20 | 1991-11-19 | Dompe Farmaceutici Spa | Procedimento per la risoluzione ottica della dropropizina. |
| DE3938123A1 (de) * | 1989-11-16 | 1991-05-23 | Diehl Gmbh & Co | Treibladungsanzuender |
| IT1318651B1 (it) * | 2000-07-28 | 2003-08-27 | Dompe Spa | Sintesi di (+-)1,3-diossolani e loro risoluzione ottica. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3163649A (en) * | 1964-12-29 | Substituteb phenyl-piperazine | ||
| GB938646A (en) * | 1961-03-16 | 1963-10-02 | Henri Morren | New piperazine derivatives |
| FR1384693A (fr) * | 1963-10-08 | 1965-01-08 | Electrochimie Soc | Procédé de préparation d'esters méthallyliques |
| FR1554628A (US20040152965A1-20040805-M00009.png) * | 1967-05-23 | 1969-01-24 |
-
1981
- 1981-02-25 IT IT8109343A patent/IT1210639B/it active
- 1981-05-22 GB GB8115803A patent/GB2093445B/en not_active Expired
- 1981-06-10 US US06/272,281 patent/US4372958A/en not_active Expired - Fee Related
-
1982
- 1982-02-13 DE DE19823205149 patent/DE3205149A1/de active Granted
- 1982-02-17 AT AT0059982A patent/AT380881B/de not_active IP Right Cessation
- 1982-02-19 PT PT74463A patent/PT74463B/pt unknown
- 1982-02-23 GR GR67396A patent/GR76060B/el unknown
- 1982-02-23 LU LU83962A patent/LU83962A1/fr unknown
- 1982-02-24 CA CA000397008A patent/CA1192549A/en not_active Expired
- 1982-02-24 JP JP57027570A patent/JPS57188589A/ja active Granted
- 1982-02-24 NL NL8200746A patent/NL8200746A/nl not_active Application Discontinuation
- 1982-02-24 DK DK79982A patent/DK148687C/da active
- 1982-02-24 YU YU412/82A patent/YU44007B/xx unknown
- 1982-02-24 ES ES509850A patent/ES8302680A1/es not_active Expired
- 1982-02-25 BE BE0/207403A patent/BE892271A/fr not_active IP Right Cessation
- 1982-02-25 SE SE8201184A patent/SE440503B/sv not_active IP Right Cessation
- 1982-02-25 CH CH1167/82A patent/CH651043A5/it not_active IP Right Cessation
- 1982-02-25 FR FR8203164A patent/FR2500455A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| SE8201184L (sv) | 1982-08-26 |
| FR2500455A1 (fr) | 1982-08-27 |
| GR76060B (US20040152965A1-20040805-M00009.png) | 1984-08-03 |
| ES509850A0 (es) | 1983-02-01 |
| JPH0333715B2 (US20040152965A1-20040805-M00009.png) | 1991-05-20 |
| ATA59982A (de) | 1985-12-15 |
| NL8200746A (nl) | 1982-09-16 |
| DK148687C (da) | 1986-04-28 |
| DE3205149C2 (US20040152965A1-20040805-M00009.png) | 1991-04-18 |
| BE892271A (fr) | 1982-06-16 |
| GB2093445A (en) | 1982-09-02 |
| CH651043A5 (it) | 1985-08-30 |
| PT74463A (en) | 1982-03-01 |
| AT380881B (de) | 1986-07-25 |
| FR2500455B1 (US20040152965A1-20040805-M00009.png) | 1984-04-27 |
| YU44007B (en) | 1990-02-28 |
| CA1192549A (en) | 1985-08-27 |
| LU83962A1 (fr) | 1982-07-08 |
| SE440503B (sv) | 1985-08-05 |
| GB2093445B (en) | 1985-02-27 |
| IT1210639B (it) | 1989-09-14 |
| DE3205149A1 (de) | 1982-11-11 |
| PT74463B (en) | 1983-08-24 |
| IT8109343A0 (it) | 1981-02-25 |
| DK79982A (da) | 1982-08-26 |
| JPS57188589A (en) | 1982-11-19 |
| YU41282A (en) | 1987-10-31 |
| DK148687B (da) | 1985-09-02 |
| US4372958A (en) | 1983-02-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed |
Effective date: 19960401 |