ES8301629A1 - "un metodo de fabricacion de una composicion farmaceutica de liberacion retardada en forma de pastillas que contiene como agente terapeutico ibuprofen o flurbiprofen". - Google Patents

"un metodo de fabricacion de una composicion farmaceutica de liberacion retardada en forma de pastillas que contiene como agente terapeutico ibuprofen o flurbiprofen".

Info

Publication number
ES8301629A1
ES8301629A1 ES509179A ES509179A ES8301629A1 ES 8301629 A1 ES8301629 A1 ES 8301629A1 ES 509179 A ES509179 A ES 509179A ES 509179 A ES509179 A ES 509179A ES 8301629 A1 ES8301629 A1 ES 8301629A1
Authority
ES
Spain
Prior art keywords
agent
ibuprofen
flurbiprofen
erosion
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES509179A
Other languages
English (en)
Other versions
ES509179A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boots Co PLC
Original Assignee
Boots Co PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/194,453 external-priority patent/US4308251A/en
Application filed by Boots Co PLC filed Critical Boots Co PLC
Publication of ES509179A0 publication Critical patent/ES509179A0/es
Publication of ES8301629A1 publication Critical patent/ES8301629A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE COMPOSICIONES A BASE DE IBUPROFEN O FLURBIPROFEN. CONSTA DE LAS SIGUIENTES OPERACIONES: 1<002> MEZCLAR EL AGENTE TERAPEUTICO IBUPROFEN O FLURBIPROFEN CON 1,0 A 7,5% EN PESO DE UN AGENTE ACTIVADOR DE LA EROSION. 2<002> GRANULAR LA MEZCLA UTILIZANDO UNA SOLUCION DE 0,8 A 1,6% EN PESO DE UN AGENTE DE CONTROL DE LA LIBERACION EN UN DISOLVENTE ORGANICO. 3<002> SECAR LA MASA GRANULADA. 4<002> COMPRIMIR DICHA MASA EN FORMA DE PASTILLA. COMO AGENTE DE CONTROL DE LIBERACION SE EMPLEA ACETATOFTALATO DE CELULOSA Y COMO AGENTE ACTIVADOR DE LA EROSION ALMIDON DE MAIZ. LAS PASTILLAS OBTENIDAS CONTIENEN DE 400 A 600 MG DE IBUPROFEN O DE 100 A 300 MG DE FLURBIPROFEN POR PASTILLA. ADICIONALMENTE PUEDEN AÑADIRSE CARGAS O DILUYENTES INERTES, AUXILIARES DE FLUJO, O AUXILIARES DE FORMACION DE PASTILLAS.
ES509179A 1980-01-11 1982-01-29 "un metodo de fabricacion de una composicion farmaceutica de liberacion retardada en forma de pastillas que contiene como agente terapeutico ibuprofen o flurbiprofen". Expired ES8301629A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11143080A 1980-01-11 1980-01-11
US06/194,453 US4308251A (en) 1980-01-11 1980-10-17 Controlled release formulations of orally-active medicaments

Publications (2)

Publication Number Publication Date
ES509179A0 ES509179A0 (es) 1982-12-16
ES8301629A1 true ES8301629A1 (es) 1982-12-16

Family

ID=26808896

Family Applications (2)

Application Number Title Priority Date Filing Date
ES498369A Granted ES498369A0 (es) 1980-01-11 1981-01-08 Un metodo de fabricacion de una composicion farmaceutica de liberacion retardada en formade pastillas que contienen aci-dos acetilsalicilico.
ES509179A Expired ES8301629A1 (es) 1980-01-11 1982-01-29 "un metodo de fabricacion de una composicion farmaceutica de liberacion retardada en forma de pastillas que contiene como agente terapeutico ibuprofen o flurbiprofen".

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES498369A Granted ES498369A0 (es) 1980-01-11 1981-01-08 Un metodo de fabricacion de una composicion farmaceutica de liberacion retardada en formade pastillas que contienen aci-dos acetilsalicilico.

Country Status (22)

Country Link
JP (1) JPS56103110A (es)
AT (1) AT374681B (es)
AU (1) AU542824B2 (es)
BE (1) BE886998A (es)
CA (1) CA1140466A (es)
CH (1) CH646604A5 (es)
DE (1) DE3100191A1 (es)
DK (1) DK6181A (es)
ES (2) ES498369A0 (es)
FI (1) FI76927C (es)
FR (1) FR2473308B1 (es)
GB (1) GB2067072B (es)
GR (1) GR73843B (es)
IE (1) IE50806B1 (es)
IN (1) IN151913B (es)
IT (1) IT1221041B (es)
LU (1) LU83052A1 (es)
NL (1) NL8100037A (es)
NO (1) NO156153C (es)
NZ (1) NZ195933A (es)
SE (1) SE447450B (es)
ZA (1) ZA81136B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2496082A (en) * 1947-05-24 1950-01-31 Ashenfelter William Scaffold structure
IT1144911B (it) * 1981-03-19 1986-10-29 Pharmatec Spa Composizione farmaceutica a rilascio controllato contenente ibuprofen
JPS59227817A (ja) * 1983-06-07 1984-12-21 Toyo Jozo Co Ltd 持続性経口用ブレデニン製剤
JPH0662404B2 (ja) * 1983-06-14 1994-08-17 シンテックス・ファーマシユーテイカルズ・インターナシヨナル・リミテツド 制御放出性ナプロキセンおよびナプロキセンナトリウム錠
ZA836030B (en) * 1983-08-16 1985-02-27 Verex Lab Constant order release solid dosage indomethacin formulation and method of treating arthritis and other inflammatory conditions
ZA836031B (en) * 1983-08-16 1985-02-27 Verex Lab Constant release rate solid dosage theophylline formulation
EP0138216B1 (en) * 1983-10-14 1993-01-07 Sumitomo Pharmaceuticals Company, Limited Sustained-release ifn preparation for parenteral administration
US5385738A (en) * 1983-10-14 1995-01-31 Sumitomo Pharmaceuticals Company, Ltd. Sustained-release injection
US4774091A (en) * 1983-10-14 1988-09-27 Sumitomo Pharmaceuticals Company, Ltd. Long-term sustained-release preparation
US4855134A (en) * 1983-10-14 1989-08-08 Sumitomo Pharmaceuticals Company, Limited Sustained-release preparation
EP0230647B1 (en) * 1985-12-27 1993-03-31 Sumitomo Pharmaceuticals Company, Limited Method for producing a sustained release formulation
GB8601204D0 (en) * 1986-01-18 1986-02-19 Boots Co Plc Therapeutic agents
CA1316110C (en) * 1987-02-27 1993-04-13 Peter Lloyd Oren Sustained release matrix formulations
US4968508A (en) * 1987-02-27 1990-11-06 Eli Lilly And Company Sustained release matrix
US5855915A (en) * 1995-06-30 1999-01-05 Baylor University Tablets or biologically acceptable implants for long-term antiinflammatory drug release

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2953497A (en) * 1953-06-03 1960-09-20 Howard A Press Therapeutic tablets
NL265428A (es) * 1960-06-06
US3577514A (en) * 1968-06-10 1971-05-04 Pfizer Sustained release pharmaceutical tablets
US3773920A (en) * 1971-07-14 1973-11-20 Nikken Chemicals Co Ltd Sustained release medicinal composition
US3906086A (en) * 1971-07-19 1975-09-16 Richard G Powers Timed-release aspirin
GB1500300A (en) * 1975-01-06 1978-02-08 Ciba Geigy Ag Pharmaceutical preparation for the treatment of circulatory disorders
JPS5411226A (en) * 1977-06-24 1979-01-27 Shin Etsu Chem Co Ltd Disintegratable granule

Also Published As

Publication number Publication date
NO156153B (no) 1987-04-27
FI76927C (fi) 1989-01-10
AU542824B2 (en) 1985-03-14
NO810062L (no) 1981-07-13
SE8100104L (sv) 1981-07-12
ATA5481A (de) 1983-10-15
NZ195933A (en) 1982-11-23
FR2473308A1 (fr) 1981-07-17
DK6181A (da) 1981-07-12
FI810056L (fi) 1981-07-12
AT374681B (de) 1984-05-25
ES509179A0 (es) 1982-12-16
AU6597681A (en) 1981-07-16
ES8205353A1 (es) 1982-06-01
IN151913B (es) 1983-09-03
DE3100191A1 (de) 1981-12-10
NL8100037A (nl) 1981-08-03
FR2473308B1 (fr) 1985-07-19
BE886998A (fr) 1981-07-08
FI76927B (fi) 1988-09-30
IE50806B1 (en) 1986-07-23
ES498369A0 (es) 1982-06-01
NO156153C (no) 1987-08-05
GB2067072A (en) 1981-07-22
IT8147537A0 (it) 1981-01-09
LU83052A1 (fr) 1982-09-10
GB2067072B (en) 1983-08-10
IE810036L (en) 1981-07-11
DE3100191C2 (es) 1988-09-01
SE447450B (sv) 1986-11-17
ZA81136B (en) 1982-01-27
GR73843B (es) 1984-05-07
IT1221041B (it) 1990-06-21
JPS56103110A (en) 1981-08-18
CA1140466A (en) 1983-02-01
CH646604A5 (fr) 1984-12-14

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