ES8301629A1 - "un metodo de fabricacion de una composicion farmaceutica de liberacion retardada en forma de pastillas que contiene como agente terapeutico ibuprofen o flurbiprofen". - Google Patents
"un metodo de fabricacion de una composicion farmaceutica de liberacion retardada en forma de pastillas que contiene como agente terapeutico ibuprofen o flurbiprofen".Info
- Publication number
- ES8301629A1 ES8301629A1 ES509179A ES509179A ES8301629A1 ES 8301629 A1 ES8301629 A1 ES 8301629A1 ES 509179 A ES509179 A ES 509179A ES 509179 A ES509179 A ES 509179A ES 8301629 A1 ES8301629 A1 ES 8301629A1
- Authority
- ES
- Spain
- Prior art keywords
- agent
- ibuprofen
- flurbiprofen
- erosion
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE COMPOSICIONES A BASE DE IBUPROFEN O FLURBIPROFEN. CONSTA DE LAS SIGUIENTES OPERACIONES: 1<002> MEZCLAR EL AGENTE TERAPEUTICO IBUPROFEN O FLURBIPROFEN CON 1,0 A 7,5% EN PESO DE UN AGENTE ACTIVADOR DE LA EROSION. 2<002> GRANULAR LA MEZCLA UTILIZANDO UNA SOLUCION DE 0,8 A 1,6% EN PESO DE UN AGENTE DE CONTROL DE LA LIBERACION EN UN DISOLVENTE ORGANICO. 3<002> SECAR LA MASA GRANULADA. 4<002> COMPRIMIR DICHA MASA EN FORMA DE PASTILLA. COMO AGENTE DE CONTROL DE LIBERACION SE EMPLEA ACETATOFTALATO DE CELULOSA Y COMO AGENTE ACTIVADOR DE LA EROSION ALMIDON DE MAIZ. LAS PASTILLAS OBTENIDAS CONTIENEN DE 400 A 600 MG DE IBUPROFEN O DE 100 A 300 MG DE FLURBIPROFEN POR PASTILLA. ADICIONALMENTE PUEDEN AÑADIRSE CARGAS O DILUYENTES INERTES, AUXILIARES DE FLUJO, O AUXILIARES DE FORMACION DE PASTILLAS.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11143080A | 1980-01-11 | 1980-01-11 | |
| US06/194,453 US4308251A (en) | 1980-01-11 | 1980-10-17 | Controlled release formulations of orally-active medicaments |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8301629A1 true ES8301629A1 (es) | 1982-12-16 |
| ES509179A0 ES509179A0 (es) | 1982-12-16 |
Family
ID=26808896
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES498369A Granted ES498369A0 (es) | 1980-01-11 | 1981-01-08 | Un metodo de fabricacion de una composicion farmaceutica de liberacion retardada en formade pastillas que contienen aci-dos acetilsalicilico. |
| ES509179A Granted ES509179A0 (es) | 1980-01-11 | 1982-01-29 | "un metodo de fabricacion de una composicion farmaceutica de liberacion retardada en forma de pastillas que contiene como agente terapeutico ibuprofen o flurbiprofen". |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES498369A Granted ES498369A0 (es) | 1980-01-11 | 1981-01-08 | Un metodo de fabricacion de una composicion farmaceutica de liberacion retardada en formade pastillas que contienen aci-dos acetilsalicilico. |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPS56103110A (es) |
| AT (1) | AT374681B (es) |
| AU (1) | AU542824B2 (es) |
| BE (1) | BE886998A (es) |
| CA (1) | CA1140466A (es) |
| CH (1) | CH646604A5 (es) |
| DE (1) | DE3100191A1 (es) |
| DK (1) | DK6181A (es) |
| ES (2) | ES498369A0 (es) |
| FI (1) | FI76927C (es) |
| FR (1) | FR2473308B1 (es) |
| GB (1) | GB2067072B (es) |
| GR (1) | GR73843B (es) |
| IE (1) | IE50806B1 (es) |
| IN (1) | IN151913B (es) |
| IT (1) | IT1221041B (es) |
| LU (1) | LU83052A1 (es) |
| NL (1) | NL8100037A (es) |
| NO (1) | NO156153C (es) |
| NZ (1) | NZ195933A (es) |
| SE (1) | SE447450B (es) |
| ZA (1) | ZA81136B (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2496082A (en) * | 1947-05-24 | 1950-01-31 | Ashenfelter William | Scaffold structure |
| IT1144911B (it) * | 1981-03-19 | 1986-10-29 | Pharmatec Spa | Composizione farmaceutica a rilascio controllato contenente ibuprofen |
| JPS59227817A (ja) * | 1983-06-07 | 1984-12-21 | Toyo Jozo Co Ltd | 持続性経口用ブレデニン製剤 |
| JPH0662404B2 (ja) * | 1983-06-14 | 1994-08-17 | シンテックス・ファーマシユーテイカルズ・インターナシヨナル・リミテツド | 制御放出性ナプロキセンおよびナプロキセンナトリウム錠 |
| ZA836031B (en) * | 1983-08-16 | 1985-02-27 | Verex Lab | Constant release rate solid dosage theophylline formulation |
| ZA836030B (en) * | 1983-08-16 | 1985-02-27 | Verex Lab | Constant order release solid dosage indomethacin formulation and method of treating arthritis and other inflammatory conditions |
| US4855134A (en) * | 1983-10-14 | 1989-08-08 | Sumitomo Pharmaceuticals Company, Limited | Sustained-release preparation |
| DE3486029T2 (de) * | 1983-10-14 | 1993-05-13 | Sumitomo Pharma | Ifn-praeparat mit verzoegerter abgabe fuer parentale verabreichung. |
| US4774091A (en) * | 1983-10-14 | 1988-09-27 | Sumitomo Pharmaceuticals Company, Ltd. | Long-term sustained-release preparation |
| US5385738A (en) * | 1983-10-14 | 1995-01-31 | Sumitomo Pharmaceuticals Company, Ltd. | Sustained-release injection |
| DE3688188T2 (de) * | 1985-12-27 | 1993-10-14 | Koken Kk | Verfahren zur Herstellung einer Formulierung mit verzögerter Freisetzung. |
| GB8601204D0 (en) * | 1986-01-18 | 1986-02-19 | Boots Co Plc | Therapeutic agents |
| ZA881301B (en) * | 1987-02-27 | 1989-10-25 | Lilly Co Eli | Sustained release matrix formulations |
| US4968508A (en) * | 1987-02-27 | 1990-11-06 | Eli Lilly And Company | Sustained release matrix |
| US5855915A (en) | 1995-06-30 | 1999-01-05 | Baylor University | Tablets or biologically acceptable implants for long-term antiinflammatory drug release |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2953497A (en) * | 1953-06-03 | 1960-09-20 | Howard A Press | Therapeutic tablets |
| NL265428A (es) * | 1960-06-06 | |||
| US3577514A (en) * | 1968-06-10 | 1971-05-04 | Pfizer | Sustained release pharmaceutical tablets |
| US3773920A (en) * | 1971-07-14 | 1973-11-20 | Nikken Chemicals Co Ltd | Sustained release medicinal composition |
| US3906086A (en) * | 1971-07-19 | 1975-09-16 | Richard G Powers | Timed-release aspirin |
| GB1500300A (en) * | 1975-01-06 | 1978-02-08 | Ciba Geigy Ag | Pharmaceutical preparation for the treatment of circulatory disorders |
| JPS5411226A (en) * | 1977-06-24 | 1979-01-27 | Shin Etsu Chem Co Ltd | Disintegratable granule |
-
1980
- 1980-12-23 IN IN1418/CAL/80A patent/IN151913B/en unknown
- 1980-12-23 NZ NZ195933A patent/NZ195933A/xx unknown
-
1981
- 1981-01-05 AU AU65976/81A patent/AU542824B2/en not_active Ceased
- 1981-01-06 FR FR8100087A patent/FR2473308B1/fr not_active Expired
- 1981-01-07 NL NL8100037A patent/NL8100037A/nl not_active Application Discontinuation
- 1981-01-07 DE DE19813100191 patent/DE3100191A1/de active Granted
- 1981-01-08 DK DK6181A patent/DK6181A/da not_active Application Discontinuation
- 1981-01-08 BE BE0/203426A patent/BE886998A/fr unknown
- 1981-01-08 JP JP157881A patent/JPS56103110A/ja active Pending
- 1981-01-08 ES ES498369A patent/ES498369A0/es active Granted
- 1981-01-08 CH CH9281A patent/CH646604A5/fr not_active IP Right Cessation
- 1981-01-08 GB GB8100522A patent/GB2067072B/en not_active Expired
- 1981-01-09 IE IE36/81A patent/IE50806B1/en unknown
- 1981-01-09 IT IT47537/81A patent/IT1221041B/it active
- 1981-01-09 ZA ZA00810136A patent/ZA81136B/xx unknown
- 1981-01-09 SE SE8100104A patent/SE447450B/sv not_active IP Right Cessation
- 1981-01-09 LU LU83052A patent/LU83052A1/fr unknown
- 1981-01-09 AT AT0005481A patent/AT374681B/de not_active IP Right Cessation
- 1981-01-09 FI FI810056A patent/FI76927C/fi not_active IP Right Cessation
- 1981-01-09 CA CA000368219A patent/CA1140466A/en not_active Expired
- 1981-01-09 GR GR63828A patent/GR73843B/el unknown
- 1981-01-09 NO NO810062A patent/NO156153C/no unknown
-
1982
- 1982-01-29 ES ES509179A patent/ES509179A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| NO156153C (no) | 1987-08-05 |
| ES8205353A1 (es) | 1982-06-01 |
| CH646604A5 (fr) | 1984-12-14 |
| IE810036L (en) | 1981-07-11 |
| NO156153B (no) | 1987-04-27 |
| DE3100191C2 (es) | 1988-09-01 |
| IT8147537A0 (it) | 1981-01-09 |
| FR2473308B1 (fr) | 1985-07-19 |
| LU83052A1 (fr) | 1982-09-10 |
| DK6181A (da) | 1981-07-12 |
| NZ195933A (en) | 1982-11-23 |
| AU542824B2 (en) | 1985-03-14 |
| IN151913B (es) | 1983-09-03 |
| GR73843B (es) | 1984-05-07 |
| AU6597681A (en) | 1981-07-16 |
| JPS56103110A (en) | 1981-08-18 |
| SE8100104L (sv) | 1981-07-12 |
| ES498369A0 (es) | 1982-06-01 |
| FI76927B (fi) | 1988-09-30 |
| DE3100191A1 (de) | 1981-12-10 |
| CA1140466A (en) | 1983-02-01 |
| GB2067072A (en) | 1981-07-22 |
| FI76927C (fi) | 1989-01-10 |
| NO810062L (no) | 1981-07-13 |
| FR2473308A1 (fr) | 1981-07-17 |
| IE50806B1 (en) | 1986-07-23 |
| SE447450B (sv) | 1986-11-17 |
| ES509179A0 (es) | 1982-12-16 |
| IT1221041B (it) | 1990-06-21 |
| FI810056L (fi) | 1981-07-12 |
| AT374681B (de) | 1984-05-25 |
| GB2067072B (en) | 1983-08-10 |
| ZA81136B (en) | 1982-01-27 |
| ATA5481A (de) | 1983-10-15 |
| NL8100037A (nl) | 1981-08-03 |
| BE886998A (fr) | 1981-07-08 |
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