ES8300699A1 - Procedimiento para la preparacion de derivados del indol. - Google Patents
Procedimiento para la preparacion de derivados del indol.Info
- Publication number
- ES8300699A1 ES8300699A1 ES504694A ES504694A ES8300699A1 ES 8300699 A1 ES8300699 A1 ES 8300699A1 ES 504694 A ES504694 A ES 504694A ES 504694 A ES504694 A ES 504694A ES 8300699 A1 ES8300699 A1 ES 8300699A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- alkyl
- hydrogen atom
- cycloalkyl
- represent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 3
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 3
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 2
- 101100134927 Gallus gallus COR8 gene Proteins 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000019695 Migraine disease Diseases 0.000 abstract 1
- 229910006074 SO2NH2 Inorganic materials 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 206010027599 migraine Diseases 0.000 abstract 1
- 125000002950 monocyclic group Chemical group 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 125000000565 sulfonamide group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8026288 | 1980-08-12 | ||
| GB8026287 | 1980-08-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES504694A0 ES504694A0 (es) | 1982-11-01 |
| ES8300699A1 true ES8300699A1 (es) | 1982-11-01 |
Family
ID=26276534
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES504694A Expired ES8300699A1 (es) | 1980-08-12 | 1981-08-11 | Procedimiento para la preparacion de derivados del indol. |
| ES513934A Expired ES8405371A1 (es) | 1980-08-12 | 1982-07-13 | Un procedimiento para la preparacion de derivados del indol. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES513934A Expired ES8405371A1 (es) | 1980-08-12 | 1982-07-13 | Un procedimiento para la preparacion de derivados del indol. |
Country Status (12)
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR79215B (enrdf_load_stackoverflow) * | 1982-06-07 | 1984-10-22 | Glaxo Group Ltd | |
| PT78358B (en) * | 1983-04-07 | 1986-05-30 | Smith Kline French Lab | Chemical process |
| HU196752B (en) * | 1983-12-06 | 1989-01-30 | Glaxo Group Ltd | Process for production of medical compositions containing indole-derivatives and these compounds |
| GB8332437D0 (en) * | 1983-12-06 | 1984-01-11 | Glaxo Group Ltd | Chemical compounds |
| GB8419575D0 (en) * | 1984-08-01 | 1984-09-05 | Glaxo Group Ltd | Chemical compounds |
| GB8600397D0 (en) * | 1986-01-08 | 1986-02-12 | Glaxo Group Ltd | Chemical compounds |
| GB8600398D0 (en) * | 1986-01-08 | 1986-02-12 | Glaxo Group Ltd | Chemical compounds |
| GB8607824D0 (en) * | 1986-03-27 | 1986-04-30 | Glaxo Group Ltd | Chemical compounds |
| US5225431A (en) * | 1987-10-23 | 1993-07-06 | Burroughs Wellcome Co. | Therapeutic substituted indole compounds and compositions thereof |
| CZ283018B6 (cs) * | 1991-02-01 | 1997-12-17 | Merck Sharp And Dohme Limited | Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi |
| GB9104136D0 (en) * | 1991-02-27 | 1991-04-17 | Merck Sharp & Dohme | Therapeutic agents |
| CA2132706C (en) * | 1992-04-10 | 1998-08-04 | John Eugene Macor | Acylaminoindole derivatives as 5-ht1 agonists |
| GB9207930D0 (en) * | 1992-04-10 | 1992-05-27 | Pfizer Ltd | Indoles |
| GB9209882D0 (en) * | 1992-05-07 | 1992-06-24 | Glaxo Lab Sa | Compositions |
| GB9211277D0 (en) | 1992-05-28 | 1992-07-15 | Glaxo Group Inc | Pharmaceutical compositions |
| IL106445A (en) * | 1992-07-30 | 1998-01-04 | Merck Sharp & Dohme | History of 1,2,4-Trans-Triazole 4-Transform, Preparation and Pharmaceutical Preparations Containing Them |
| ES2070772B1 (es) * | 1993-08-09 | 1996-02-16 | Pfizer | Derivados de acilaminoindol |
| AU699281B2 (en) * | 1994-12-06 | 1998-11-26 | Merck Sharp & Dohme Limited | Azetidine, pyrrolidine and piperidine derivatives as 5HT1 receptor agonists |
| FR2731224B1 (fr) * | 1995-03-02 | 1997-05-30 | Pf Medicament | Nouveaux derives bi-tryptaminiques sulfonamides, leur procede de preparation et leur utilisation a titre de medicaments |
| US7189753B1 (en) | 1997-11-06 | 2007-03-13 | Cady Roger K | Preemptive prophylaxis of migraine |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2870162A (en) * | 1954-04-28 | 1959-01-20 | Upjohn Co | Production of certain tryptamines and compounds produced in the process |
| FR1203195A (fr) * | 1958-07-25 | 1960-01-15 | Chimiotherapie Lab Franc | Procédé de préparation d'un nouveau dérivé de la tryptamine |
| NL7316677A (enrdf_load_stackoverflow) * | 1972-12-21 | 1974-06-25 | ||
| ZA795239B (en) * | 1978-10-12 | 1980-11-26 | Glaxo Group Ltd | Heterocyclic compounds |
-
1981
- 1981-08-11 DE DE19813131752 patent/DE3131752A1/de active Granted
- 1981-08-11 GB GB8124478A patent/GB2083463B/en not_active Expired
- 1981-08-11 SE SE8104783A patent/SE454777B/sv not_active IP Right Cessation
- 1981-08-11 FR FR8115515A patent/FR2488606A1/fr active Granted
- 1981-08-11 NZ NZ197998A patent/NZ197998A/en unknown
- 1981-08-11 IT IT49085/81A patent/IT1171450B/it active
- 1981-08-11 IE IE1832/81A patent/IE51493B1/en unknown
- 1981-08-11 AU AU73995/81A patent/AU550010B2/en not_active Ceased
- 1981-08-11 ES ES504694A patent/ES8300699A1/es not_active Expired
- 1981-08-11 DK DK357281A patent/DK157995C/da not_active IP Right Cessation
- 1981-08-11 NL NL8103764A patent/NL8103764A/nl not_active Application Discontinuation
- 1981-08-11 CH CH5161/81A patent/CH652394A5/fr not_active IP Right Cessation
-
1982
- 1982-07-13 ES ES513934A patent/ES8405371A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU550010B2 (en) | 1986-02-27 |
| SE454777B (sv) | 1988-05-30 |
| ES504694A0 (es) | 1982-11-01 |
| IE51493B1 (en) | 1987-01-07 |
| IT8149085A0 (it) | 1981-08-11 |
| DK157995C (da) | 1990-08-06 |
| FR2488606B1 (enrdf_load_stackoverflow) | 1984-10-26 |
| NZ197998A (en) | 1985-08-16 |
| DK157995B (da) | 1990-03-12 |
| DE3131752A1 (de) | 1982-06-16 |
| IT1171450B (it) | 1987-06-10 |
| DK357281A (da) | 1982-02-13 |
| NL8103764A (nl) | 1982-03-01 |
| CH652394A5 (fr) | 1985-11-15 |
| GB2083463B (en) | 1984-05-10 |
| IE811832L (en) | 1982-02-12 |
| DE3131752C2 (enrdf_load_stackoverflow) | 1992-04-23 |
| GB2083463A (en) | 1982-03-24 |
| AU7399581A (en) | 1982-02-18 |
| ES513934A0 (es) | 1984-06-01 |
| FR2488606A1 (fr) | 1982-02-19 |
| ES8405371A1 (es) | 1984-06-01 |
| SE8104783L (sv) | 1982-02-13 |
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